“Toward a Better Understanding of Drug Metabolism and Transport: Novel Model Systems, Environmental Influence, and Liability Prediction”

Venue: Hotel Somerset Bridgewater (formerly Crowne Plaza, formerly Somerset Plaza), 110 Davidson Avenue, Somerset, NJ 08873
Click here for: Directions | Registration

Date: Held on October 11, 2012, 8:00 am – 3:45 pm

Exhibitor Info

Please contact Karen Dingley at karen_dingley@merck.com for information concerning exhibits.

Registration Fees & Info

  • Pre-registration fee is $125 (by October 5, 2012). Registration is free for students and unemployed (with proper identification). Registration fee at the door is $150 (Checks only).
  • Checks should be made payable to: NJ Drug Metabolism Discussion Group.
  • Please plan to pre-register as a group, as coordinated by a member of the NJACS DMDG steering committee from your organization (see list above).
  • If you have no DMDG member at your company, please contact Allen Jones (allen.n.jones@verizon.net for registration.
  • Payments by personal or company checks. Sorry, credit cards are not accepted.


08:00 am
Registration / Continental Breakfast / Vendor Exhibit

09:00 am
Introductory Remarks
Dr. Allen Jones, Chair, NJDMDG

09:10 am
“Investigating Chemotherapeutic Drug Disposition and Toxicity using Transporter Knockout and Humanized Mice”
Dr. Lauren Aleksunes, Assistant Professor
Ernest Mario School of Pharmacy, Rutgers University, Piscataway, NJ

10:00 am
“Evolving Trends in Complex Culture Systems and Their Utility in Drug Development: Focus on hepatotoxicity”
Mr. Albert Reising, Lab Head- Models of Organ Toxicity
Novartis Pharmaceuticals, East Hanover, NJ

10:45 am
Vendor Exhibit & Coffee Break

11:30 am
“Identifying and Eliminating Biotransformation Liabilities Early in Drug Discovery”
Dr. Kaushik Mitra, Department of Pharmacodynamics, Pharmacokinetics and Drug Metabolism
Merck, Rahway, NJ

12:15 pm
Lunch & Vendor Exhibit

01:45 pm
“Induction of Mouse Carboxylesterase Expression and Function following Developmental Pesticide Exposure: Role of the Constitutive Androstane Receptor the role of environment and development in regulating metabolism”
Dr. Jason Richardson, Assistant Professor
Department of Environmental and Occupational Medicine, Robert Wood Johnson Medical School, and Resident Member Environmental and Occupational Health Sciences Institute, Piscataway, NJ

02:30 pm
Vendor Exhibit & Coffee Break

03:00 pm
“UGT phenotyping, clearance predictions and DDI assessment”
Dr. Theunis Goosen, Associate Research Fellow

03:45 pm
Program Closure

Directions to the Hotel Somerset Bridgewater

Hotel Somerset Bridgewater was formerly Crowne Plaza, formerly Somerset Plaza
110 Davidson Avenue, Somerset, NJ 08873
Phone: 732-560-0500

  • From the New Jersey Turnpike:
    Exit 10 to Interstate 287 North. Follow 10 miles to Exit 10 (527 New Brunswick-South Bound Brook). Easton Ave towards South Bound Brook to first light, make left (Davidson Ave.)
  • From New York City:
    Lincoln Tunnel to N.J. Turnpike South. Follow N.J. Turnpike directions mentioned above.
  • From Route 287:
    • If traveling north: Exit 10 (527 New Brunswick-South Bound Brook). Follow sign towards Bound Brook, to light make left (Davidson Ave.)
    • If traveling south: Exit 10 (527 New Brunswick). Left on Easton Ave., to light, make left (Davidson Ave).
  • From the Newark Airport
    Take NJ Turnpike South to Exit 10- I-287 North to Exit 10 (Easton Ave) to first light, go left on Davidson Ave. Hotel immediately on left.