- Home
- News & Views
- Topical Groups
- Education
- Careers
- Quick Links, etc
(Recent Event)
Jan 27, 2023 – NMR Topical Group Meeting
The North Jersey ACS NMR Topical Group is pleased to present its January meeting online, Fri, January 27, 12:00 noon ET, via Microsoft Teams. (Note: This meeting was originally listed for Thurs Jan 26)
Featured Presentation

Seminar details:
Date: Friday January 27 at 12:00 noon ET
Speaker: Christine Jorge
Bristol Myers Squibb
Title: “Analytical Characterization of Macrocyclic Peptidomimetic Compounds by NMR Spectroscopy”
Flyer:
Abstract
In an effort to develop novel therapeutics to complex biological targets, many new drug
modalities that extend beyond traditional small molecule drugs have gained popularity within
the drug discovery landscape. Amongst these, peptide-based drugs offer an attractive means
of inhibiting protein:protein interactions of featureless protein surfaces and constitute ~10% of
new drug approvals in the past 2 years. The hybrid features of peptido-mimetic drugs make
analytical and structural characterization using standard small molecule or protein techniques
difficult, and a robust analytical toolkit is needed. Herein, we describe several NMR based
applications to the characterization of conformationally constrained cyclic peptidomimetic
compounds including: 1) concentration determination and purity workflows, 2) triaging of well-
behaved single conformer compounds by 1D proton spectral screening, 3) qualitative structural
characterization for medium throughput analysis and 4) generation of full 3D structural
ensembles on well behaved drug leads. These methods have been applied to address
numerous questions in the early discovery process.
Connection Information
This will be a virtual meeting hosted via Microsoft Teams
The seminar is free of charge. No advance registration is required.
Link to the meeting (uses Microsoft Teams):
Register
Please [ register here ] for this meeting
Registration
Please [ register here ] for this meeting
Advance registration is not required.
Questions:
Jonathan.OsbornPopp (Chair)
Christine.Jorge@bms.com (Co-Chair)
Microsoft Teams meetingJoin on your computer or mobile app Click here to join the meeting: https://njacs.org/nmr-meetup Or call in (audio only) +1 908-409-1059,,228369724# United States, Elizabeth NJ (833) 733-5876,,228369724# United States (Toll-free) Phone Conference ID: 237 755 562 33# Passcode: yabLJk Find a local number | Reset PIN Audio for this meeting can be heard in the Microsoft Teams client. Please check your audio device settings before you join the call. If you see phone numbers above, you can use them to join the meeting’s audio if necessary. |
(Past Events)
Oct 24, 2022 – NMR Symposium
North Jersey ACS NMR Topical Group
presents its
Annual NMR Symposium
Monday October 24th, 2022
Frick Chemistry Building
Princeton University, Princeton, NJ 08544
[ directions | register | flyer ]
The Symposium and dinner are FREE of charge to all attendees* * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * *
Afternoon session (1:00 – 5:15 pm)

Hari Arthanari
Dana-Farber
Kevin Gardner
CUNY – ASRC
Tatyana Polenova
U. Delaware
Frank Delaglio
NIST
Lauren Marbella
Columbia U.

Evening Keynote session (5:30 – 6:45 pm)

Mei Hong
MIT
* * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * *
Dinner (7:00 – 8:30 pm), Frick Chemistry Atrium
Dinner is free of charge thanks to the generosity of our sponsors.
* * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * *
Please register for the meeting and dinner here: [ register ]
Questions? Contact: Jonathan.Williams@bms.com or Thomas.Osbornpopp@rutgers.edu
* * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * *
We acknowledge the generous support of our sponsors:






x
(Past Events)
Sept 29, 2022 – NMR Topical Group Meeting
The North Jersey ACS NMR Topical Group is pleased to present its September meeting in-person, Thurs, September 29, 2022, 6:00 pm
Featured Presentation

“Making the Most of the D1 Delay”
Speaker: Nicole Kruse, Bruker BioSpin
Date: Thursday September 29th
Time: 6:00 pm ET – Dinner
7:00 pm ET – Seminar
Place: In-person @ Rutgers University
Tillet Hall, Room 226
Bruker night!
Meeting Information
Join us as we resume our in-person meetings with Bruker Night! Come join your fellow NMR enthusiasts for an evening of fellowship and science! It has been a long time since we have been able to meet in person, and we are looking forward to seeing everyone face to face again. Bruker will be sponsoring a dinner to begin at 6:00 PM ET, followed by a seminar from Nicole Kruse (Bruker BioSpin); see abstract below. The dinner and seminar will take place at Rutgers University in Tillet Hall Room 226, on the Livingston campus. Please park in Lot 101 (Google Maps Plus Code for directions: GHC7+QJ Piscataway, New Jersey). Please reach out to Jonathan Williams (jwilliams@njacs.org) or Tom Osborn Popp (thomas.osbornpopp@rutgers.edu) with any questions. Please help spread the word to your colleagues, and we look forward to seeing you there!
Abstract
Summer is over, but that doesn’t mean we have to constantly be working. This is especially true in NMR, where that D1 delay is critical for our spins to relax back to equilibrium prior to collecting data again. This talk will cover a few different ways of determining T1 to optimize that delay. And then take a closer look at the various NOAH experiments that aim to get the most information out of that single delay.
This seminar is free of charge and sponsored by
Register
Please [ register here ] for this meeting
Questions:
Bradley.Falk@bms.com (Chair)
Jon.Williams@rutgers.edu (Co-Chair)
(Past Events)
May 19, 2022 – NMR Topical Group Meeting
The North Jersey ACS NMR Topical Group is pleased to present its May meeting online, Thurs, May 19, 12:00 noon ET
Featured Presentation

Seminar details:
Date: Thursday May 19th at 12:00 noon ET
Speaker: Prof. David A. Case
Department of Chemistry & Chemical Biology
Rutgers University
Title: “Connecting Chemical Shifts to Structure for Proteins and Nucleic Acids”
Flyer:
Abstract
An automated fragmentation quantum mechanics/molecular mechanics approach (AFNMR) has shown promising results in chemical shift calculations for biomolecules. Trends in chemical shift are stable with regards to change in density functional or basis sets, and the use of the small “pcSseg-0” basis, which was optimized for chemical shift prediction, opens the way to more extensive conformational averaging, which can often be necessary, even for fairly well-defined structures. There have also been recent advances in the use of machine learning approaches to develop empirical connections to structure. I will discuss prospects for using both types of calculations to gain insights into biomolecular structure and dynamics.
Connection Information
This will be a virtual meeting hosted via Microsoft Teams.
The seminar is free of charge. No advance registration is required.
Link to the meeting (uses Microsoft Teams):
Register
Please [ register here ] for this meeting
Registration
Please [ register here ] for this meeting
Advance registration is not required.
Questions:
Jonathan.Williams@bms.com (Chair)
Thomas.OsbornPopp@rutgers.edu (Co-Chair)
Microsoft Teams meetingJoin on your computer or mobile app Click here to join the meeting: https://njacs.org/nmr-meetup Or call in (audio only) +1 908-409-1059,,470936412# United States, Elizabeth NJ Phone Conference ID: 867 963 351# Find a local number | Reset PIN Audio for this meeting can be heard in the Microsoft Teams client. Please check your audio device settings before you join the call. If you see phone numbers above, you can use them to join the meeting’s audio if necessary. |
(Past Events)
Apr 21, 2022 – NMR Topical Group Meeting
The North Jersey ACS NMR Topical Group is pleased to present its April meeting online, Thurs, April 21, 12:00 noon ET
Featured Presentation

Seminar details:
Date: Thursday April 21st at 12:00 noon ET
Speaker: Prof. Claudia Avalos
Department of Chemistry
New York University
Title: “Improving the Spatial Specificity
Flyer:
Abstract
In this presentation I will review advances in the detection of surfaces and interfaces using solid-state NMR and how these techniques have been applied in materials science. In particular, I will discuss NMR signal enhancement using cross-effect dynamic nuclear polarization (DNP), as well as methods for generating non-equlibrium electron spin polarization optically with nitrogen-vacancy (NV) centers in diamond and designer chromophore-radical systems.
Connection Information
This will be a virtual meeting hosted via Microsoft Teams.
The seminar is free of charge. No advance registration is required.
Link to the meeting (uses Microsoft Teams):
Register
Please [ register here ] for this meeting
Registration
Please [ register here ] for this meeting
Advance registration is not required.
Questions:
Jonathan.Williams@bms.com (Chair)
Thomas.OsbornPopp@rutgers.edu (Co-Chair)
Microsoft Teams meetingJoin on your computer or mobile app Click here to join the meeting: https://njacs.org/nmr-meetup Or call in (audio only) +1 908-409-1059,,478660434# United States, Elizabeth NJ Phone Conference ID: 867 963 351# Find a local number | Reset PIN Audio for this meeting can be heard in the Microsoft Teams client. Please check your audio device settings before you join the call. If you see phone numbers above, you can use them to join the meeting’s audio if necessary. |
(Past Events)
Mar 24, 2022 – NMR Topical Group Meeting
The North Jersey ACS NMR Topical Group is pleased to present its March meeting online, Thurs, March 24, 7:00 pm
Featured Presentation

Seminar details:
Date: Thursday March 24th 7:00 pm ET
Speaker: Prof. Galia Debelouchina
Department of Chemistry & Biochemistry
University of California, San Diego
Title: “NMR-Based Tools for Structural Biology of Complex Systems: From Gels to Cells”
Flyer:
Abstract
Recent advances in structural biology have dramatically expanded the scope of proteins and assemblies that are now amenable to structural analysis. Yet, many biological systems display dynamics and undergo transformations that have been difficult to capture experimentally, especially in complex or native settings. In this context, my group has been developing NMR-based methodologies to describe such challenging systems and to pave the way to the next exciting structural biology frontier, the cellular environment. Here, I will present our progress on two fronts: 1) Development of NMR methodologies to describe the molecular basis of protein phase transitions from the liquid to the gel and solid states. In particular, I will focus on the transitions displayed by heterochromatin protein 1α (HP1α), a key player in gene regulation and chromatin organization. 2) Development of sensitivity-enhanced NMR approaches suitable for the cellular environment. Our work is based on a methodology called dynamic nuclear polarization (DNP) which can transfer polarization from electron to nuclear spins and thus increase nuclear signals by several orders of magnitude. For this purpose, we develop small molecule DNP polarization agents that contain unpaired electron spins and that can be targeted selectively to a protein of interest. These agents have allowed us to obtain NMR structural data of tiny amounts of proteins (1-5 μg) and to study the polarization transfer mechanisms in targeted DNP experiments.
Connection Information
This will be a virtual meeting hosted via Microsoft Teams.
The seminar is free of charge. No advance registration is required.
Link to the meeting (uses Microsoft Teams):
https://njacs.org/nmr-2022-03-24
Register
Please [ register here ] for this meeting
Registration
Please [ register here ] for this meeting
Advance registration is not required.
Questions:
Jonathan.Williams@bms.com (Chair)
Thomas.OsbornPopp@rutgers.edu (Co-Chair)
Microsoft Teams meetingJoin on your computer or mobile app Click here to join the meeting Or call in (audio only) +1 908-409-1059,,867963351# United States, Elizabeth NJ Phone Conference ID: 867 963 351# Find a local number | Reset PIN Audio for this meeting can be heard in the Microsoft Teams client. Please check your audio device settings before you join the call. If you see phone numbers above, you can use them to join the meeting’s audio if necessary. |
(Past Events)
Feb 24, 2022 – NMR Topical Group Meeting
The North Jersey ACS NMR Topical Group is pleased to present its February meeting online, Thurs, February 24, 7:00 pm
Featured Presentation

Seminar details:
Date: Thursday February 24th 7:00 pm ET
Speaker: Dr. Keith Fritzsching
Senior Member –Technical Staff
Sandia National Laboratories
Title: “Structure and Chemical Kinetics of Heterogenous Biomolecular Assemblies with Solid-State NMR”
Flyer:
Abstract
Solid-state NMR can be used to measure atomic-resolution structure and chemical kinetics in a broad range of systems, including those that lack periodicity, have defects, or otherdisorders. I will dicuss biophysics studies where detailed local conformational information is attenable despite long-range (nm-µm) disorder. I will highlight our recent study of TIA1, aprotein involved in several neurodegenerative diseases. Even in this large (43kDa) and complex protein, we could obtain site-specific information necessary for understanding the protein’s mechanisms and ligand binding. I will also discuss several Solid-state NMR methods development projects. I will introduce a class of recoupling pulse sequences that use an “interleaving” scheme to tune effective Hamiltonian scaling factors.
Connection Information
This will be a virtual meeting hosted via Microsoft Teams.
The seminar is free of charge. No advance registration is required.
Link to the meeting (uses Microsoft Teams):
https://njacs.org/nmr-2022-02-24
Register
Please [ register here ] for this meeting
Registration
Please [ register here ] for this meeting
Advance registration is not required.
Questions:
Jonathan.Williams@bms.com (Chair)
Thomas.OsbornPopp@rutgers.edu (Co-Chair)
Microsoft Teams meetingJoin on your computer or mobile app Click here to join the meeting Or call in (audio only) +1 908-409-1059,,867963351# United States, Elizabeth NJ Phone Conference ID: 867 963 351# Find a local number | Reset PIN Audio for this meeting can be heard in the Microsoft Teams client. Please check your audio device settings before you join the call. If you see phone numbers above, you can use them to join the meeting’s audio if necessary. |
(Past Events)
Jan 20, 2022 – NMR Topical Group Meeting
The North Jersey ACS NMR Topical Group is pleased to present its January meeting online, Thurs, January 20, 7:00 pm UNDER CONSTRUCTION
Featured Presentation

Seminar details:
Date: Thursday January 20th 7:00 pm ET
Speaker: Dr. Tom Popp
NMR Topical Group Co-Chair 2022
Rutgers University
Department of Chemistry & Chemical Biology
Title: “Development of NMR Instrumentation to Study Complex Materials”
Flyer:
Abstract
Many functional inorganic and biological materials are also highly complex in structure and composition on length scales of nanometers or greater. Solid state NMR is particularly well-suited to study these materials, due to its ability to observe local structure and site-specific dynamics. In this talk, I will share how solid-state NMR can be used to reveal new details about complex materials ranging from crystalline, porous metal-organic frameworks (MOFs) to arthropod silk and bacterial biomass. I will also describe new developments in solid state NMR instrumentation, including a new paradigm for magic-angle spinning (MAS) experiments: spherical MAS rotors.
Connection Information
This will be a virtual meeting hosted via Microsoft Teams.
The seminar is free of charge. No advance registration is required.
Link to the meeting (uses Microsoft Teams):
https://njacs.org/nmr-2022-01-20
Register
Please [ register here ] for this meeting
Registration
Please [ register here ] for this meeting
Advance registration is not required.
Questions:
Jonathan.Williams@bms.com (Chair)
Thomas.OsbornPopp@rutgers.edu (Co-Chair)
Microsoft Teams meetingJoin on your computer or mobile app Click here to join the meeting Or call in (audio only) +1 908-409-1059,,867963351# United States, Elizabeth NJ Phone Conference ID: 867 963 351# Find a local number | Reset PIN Audio for this meeting can be heard in the Microsoft Teams client. Please check your audio device settings before you join the call. If you see phone numbers above, you can use them to join the meeting’s audio if necessary. |
(Past Events)
Oct 18, 2021 – NMR Virtual Symposium
The North Jersey ACS NMR Topical Group is pleased to presents its
Under Construction
North Jersey ACS NMR Topical Group
presents the
2021 Virtual NMR Symposium
October 18th, 2021
Microsoft Teams link:
Attendance is FREE of charge
Please circulate our ]
Please [ register here ] for this symposium
Note: You can view complete videos of these talks by clicking the video links below.
Program
Session 1 (8:00 – 10:00am EDT)
8:10 – 9:00am - Christian Griesinger, Max Planck Institute [ video ]
Title: TBA
9:05 – 9:55am Matthias Ernst, ETH Zurich [ video ]
Residual Dipolar Line Width in Proton MAS Solid-State NMR
9:55 – 10:15am – Break
Session 2 (10:15 – 12:05pm EDT)
10:20 – 11:10am - Lewis Kay, University of Toronto [ video ]
Developing the NMR toolkit to study protein molecules in the phase separated state
11:15 – 12:05pm - Ann McDermott, Columbia University [ video ]
Signaling in Biological Systems – Insights from NMR
12:05 – 1:00 pm - Lunch Break
Session 3 (1:00 – 2:40pm EDT)
1:05 – 1:45pm - Nicholas Whiting, Rowan University [ video ]
Advances in Hyperpolarized Magnetic Resonance
1:50 – 2:40pm - Qi Zhang, University of North Carolina at Chapel Hill [ video ]
Unveiling the “Invisible” Regulatory States in RNA
2:40 – 3:00pm – Break
Session 4 (3:00 – 4:50pm EDT)
3:05 – 3:55pm - Andrew Nieuwkoop, Rutgers University [ video ]
Using NMR and Molecular Dynamics to Understand Protein Lipid Interactions
4:00 – 4:50pm - David Rovnyak, Bucknell University [ video ]
The metabolome in the freezer: promises and pitfalls of mining metabolic knowledge in standard-of-care biobanked sera, and other unconventional NMR metabolomics
4:50 – 5:10pm – Break
Evening Keynote (5:10 – 6:30pm EDT)
5:25 – 6:15pm – Gerhard Wagner, Harvard University [ video ]
From NMR studies of translation initiation factors to understanding
6:20 – 6:30pm – Jon Williams, Co-Chair of the NJACS NMR Topical Group
Closing remarks
x
(Past Events)
Sept 23, 2021 – NMR Topical Group Meeting
The North Jersey ACS NMR Topical Group is pleased to present its September meeting online, Thurs, September 23, 2021, 7:00 pm
Featured Presentation

Seminar details:
Date: Thursday September 23rd 7:00 pm ET
Speaker: Dr. James Kempf, Product Manager for
Title: “Nuclear magnetic resonance and hyperpolarization”
Slides:
Abstract
Nuclear magnetic resonance, with focus on hyperpolarization. Responsibility for product development in dissolution DNP, parahydrogen, brute-force hyperpolarization and other emerging methods in nuclear spin hyperpolarization. Leading internal R&D and external co-development and testing through customer collaborations.
This seminar is free of charge and sponsored by
Link to the meeting (uses Microsoft Teams):
https://njacs.org/nmr-2021-09-23
Register
Please [ register here ] for this meeting
Registration
Please [ register here ] for this meeting
Questions:
Bradley.Falk@bms.com (Chair)
Jon.Williams@rutgers.edu (Co-Chair)
Microsoft Teams meetingJoin on your computer or mobile app Click here to join the meeting Or call in (audio only) +1 908-409-1059,,402833072# United States, Elizabeth (833) 733-5876,,402833072# United States (Toll-free) Phone Conference ID: 402 833 072# Find a local number | Reset PIN Audio for this meeting can be heard in the Microsoft Teams client. Please check your audio device settings before you join the call. If you see phone numbers above, you can use them to join the meeting’s audio if necessary. |