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(Past Events)
Oct 20, 2020 – NMR Virtual Symposium

North Jersey ACS NMR Topical Group
presents the
2020 Virtual NMR Symposium
October 20th, 2020
Link to webex: https://njacs.org/nmr-symposium-webex
Password: NJACS-2020
Attendance is FREE of charge
]
Program 2020 Virtual NMR Symposium |
|
Session 1 (8:00 - 10:50 am EST) - Chair: István Pelczer, Princeton University |
|
8:00 am |
![]() Opening remarks
Justyna Sikorska,
Chair
|
8:10 am |
![]() 1. Detection of metabolic reprogramming associated with HBV infection using metabonomics
Yulan Wang,
|
8:50 am |
![]() 2. NMR As Mechanistic Tool In Photocatalysis
Ruth M. Gschwind,
|
9:30 am |
![]() 3. Ultraclean pure shift NMR?
Gareth Morris,
|
10:10 am |
![]() 4. Fast NMR: Solving a puzzle with most of the parts missing
Vladislav Y. Orekhov,
|
10:50 am |
Break (20 min) |
Session 2 (11:10 am - 12:10 pm EST) - Chair: Gaetano T. Montelione, RPI |
|
11:10 am |
![]() 5. Intrinsically disordered proteins by NMR: What can 13C direct detection tell us?
Isabella C. Felli,
|
11:50 am |
![]() 6. Integrative modelling of biomolecular complexes
Alexandre Bonvin,
|
12:30 pm |
![]() 7. High molecular-weight complexes in the regulation of gene expression: A view by integrative structural biology
Teresa Carlomagno,
|
1:10 pm |
Break (50 min) |
Session 3 (2:00 - 4:00 pm EST) - Chair: Mark McCoy, Merck & Co. |
|
2:00 pm |
![]() 8. Mechanochemical Synthesis of Active Pharmaceutical Ingredients and their Characterization with New NMR Crystallographic Methods based on Solid-State NMR of Quadrupolar Nuclei
Robert W. Schurko,
|
2:40 pm |
![]() 9. Deuterium Metabolic Imaging (DMI), a novel MR-based method to map metabolism in 3D
Robin A. de Graaf,
|
3:20 pm |
![]() 10. How Quantitative NMR Enables New Metabolomics Methods
Daniel Raftery,
|
4:00 pm |
Break (20 min) |
Session 4 (4:20 - 7:00 pm EST) - Chair: Luciano Mueller, Bristol-Myers Squibb |
|
4:20 pm |
![]() 11. Accelerated Identification of Natural Products using Small Molecule Accurate Recognition Technology (SMART) 2.1
William Gerwick,
|
5:00 pm |
![]() 12. Discovery and characterization of active small molecule ligands targeting the function of ubiquitin specific protease USP7 by a catalytic site independent mechanism
Till Maurer,
|
5:40 pm |
![]() 13. Keynote: NMR-based screening of combinatorial libraries to target protein-protein interactions with reversible or covalent agents
Maurizio Pellecchia,
|
6:40 pm |
![]() 13. Closing remarks
Bradley Falk,
Co-chair
|
7:00 pm |
End |
We acknowledge the generous support of our sponsors:














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(Past Events)
Sep 23, 2020 – NMR Topical Group Meeting
The North Jersey ACS NMR Topical Group is pleased to presents its September meeting online, Wed, Sept 23, 2020, 6:30 – 8:00 pm
Featured Presentation
Speaker: Dr. Alexander Marchanka, Junior Professor, Institute of Organic Chemistry, Leibniz Universität, Hannover, Germany
Title: “Solid-state NMR approach for structural studies
Abstract
Large RNA molecules are challenging objects for structural biology. Solid-state NMR (ssNMR) can provide valuable structural information for large biomolecules at atomic resolution and holds great promises for structural studies of both lone RNA and RNA in complex with proteins (ribonucleoproteins, RNP). In this talk I will present our novel ssNMR methodology for structural characterization of RNA which includes sophisticated isotope labeling of RNA and acquisition of multidimensional heteronuclear correlation spectra. Additionally to conventional 13C and 15N detected ssNMR experiments we apply novel ultrafast magic angle spinning (MAS), 1H-detected ssNMR spectroscopy for structural studies of RNA. Ultrafast MAS coupled with 1H-detection extends the range of available experiments, allows deeper insights into structure and functional dynamics and significantly reduces the amount of laboratory and instrument times. Furthermore, we apply paramagnetic relaxation enhancement (PRE) to characterize protein-RNA interfaces by ssNMR. Finally, I will provide a few examples of studies on RNA, protein-RNA and RNA-RNA complexes by ssNMR and complementary techniques..
Seminar details:
Time:
6:30pm 9/23/2020 EST (Princeton),
3:30pm 9/23/2020 PST (San Francisco),
12.30am 9/24/2020 CEST (Berlin),
7.30am 9/24/2020 JST (Tokyo)
The seminar is free of charge and sponsored by NJACS NMR Topical Group and Merck
Link to the webinar:
https://merck.webex.com/merck/onstage/g.php?MTID=e61294f82250cbfdfa4437e599cda6263
Password: NJACS-2020
Register
No registration required
Questions:
Justyna.Sikorska@merck.com (Chair)
Bradley.Falk@bms.com (Co-Chair)
(Past Events)
Mar 25, 2020 – NMR Topical Group Meeting CANCELLED
Meeting cancelled due to coronavirus outbreak.

Featured Presentation
Speaker: Dr. Robin A. de Graaf, Professor of Radiology and Biomedical Imaging, Yale University
Title: “Deuterium Metabolic Imaging (DMI), a novel
Abstract
Non-invasive imaging of metabolic pathways in neurological disease has been a long-standing goal to monitor disease progression or therapy efficacy. Positron emission tomography (PET) in combination with 2-18F-fluoro-2-deoxy-D-glucose (FDG) is currently the only clinically viable metabolic imaging method. However, the high uptake of FDG by normal brain drastically reduces the image contrast and the usefulness of FDG-PET in studying neurological disease. MR-based methods (1H, 13C, hyperpolarized 13C MRS) are promising but have failed to reach clinical significance due to technical complexity and lack of robustness and/or sensitivity. Deuterium metabolic imaging (DMI) is a novel MR-based method that uses the favorable MR characteristics of deuterium to map metabolism in vivo in 3D. The low intrinsic sensitivity of 2H NMR is offset by favorable T1 and T2 relaxation times, a large nuclear spin and a sparse NMR spectrum devoid of strong water and lipid signals. By combining 2H NMR with deuterated glucose administration (oral or intravenous), MR spectroscopic imaging and signal quantification through spectral fitting we were able to generate deuterium metabolic images of brain, brain tumor and liver metabolism in vivo. Our first-in-human DMI maps of glucose metabolism in healthy brain and in patients with high grade brain tumors illustrate that DMI has the potential to become a robust and widely applicable brain imaging method with strong clinical utility.
Program
6:00 pm Dinner + Retirement cake for George Anastasi
6:45 pm Raffle
7:00 pm Seminar (No charge for seminar only)
Dinner Cost (pay at the door):
$10 employed / $5 students, postdoc, retired, unemployed. No charge for seminar only.
Meeting Venue
Rutgers University
Department of Chemistry and Chemical Biology, CCB
Room 1203
123 Bevier Rd
Piscataway, NJ 08854
Parking: Parking will be available in LOT 54 (described in Driving Directions)
Important: Please register your car in advance with Rutgers Parking Department at:
https://rudots.nupark.com/events/Events/Register/afda8f8d-d782-4f00-942b-58eef60339de
Questions:
Justyna.Sikorska@merck.com (Chair)
Bradley.Falk@bms.com (Co-Chair)
Register:
Please register online [ here ] or via e-mail to
Justyna.Sikorska@merck.com (Chair)
Bradley.Falk@bms.com (Co-Chair)
(Past Events)
Feb 19, 2020 – NMR Topical Group Meeting
The North Jersey ACS NMR Topical Group is pleased to presents its February meeting at Rutgers, Wednesday, February 19, 2020
Featured Presentation
Speaker: Dr. Abby R. O’Connor, Associate Professor, Department of Chemistry, The College of New Jersey
Title: “Examining sulfonamide containing ligand scaffolds in catalytic base-free transfer hydrogenation and beyond !”
Abstract
Work in the O’Connor lab has focused on the catalysis of iridium complexes containing pyridinesulfonamide ligands. We discovered iridium-catalyzed transfer hydrogenation of polar substrates under conditions that do not require basic additives and rigorously dried and degassed substrates and solvents. These catalysts tolerate a wide substrate scope and including base sensitive functional groups. Variation of the electronics of the catalysts and substrates influences the yield of product, as determined by 1H NMR spectroscopy. Control experiments support a homogeneous catalyzed pathway. Variation of the structural rigidity of the ligand framework has been explored and high catalysis activity is only observed with flexible ethylene or methylene linkers between the sulfonamide and pyridine moieties; substitution with a more rigid aromatic linker prevents catalysis (Figure 1). Initial NMR spectroscopic studies support the formation of an iridium hydride intermediate and the potential for ligand dissociation under catalytic conditions. Our preliminary mechanistic and kinetic findings via experiment and theory are highlighted to provide an explanation as to why these systems operate under base-free conditions. Also highlighted in this presentation are new ligand scaffolds being developed by our lab for rare earth element binding and recovery and CO2 reduction.
Program
6:00 pm Dinner
7:00 pm Seminar
Dinner Cost (pay at the door):
$10 employed / $5 students, postdoc, retired, unemployed. No charge for seminar only.
Meeting Venue
Rutgers University
Department of Chemistry and Chemical Biology, CCB
Room 1203
123 Bevier Rd
Piscataway, NJ 08854
Parking: Parking will be available in LOTS 54 & 51B (described in Driving Directions)
Important: If you are driving, before leaving home please read & heed this message from the Rutgers Parking Department:
“Guests must use the below link to register for the event. Until this process is completed their vehicles are not registered and your guests may receive a
https://rudots.nupark.com/events/Events/Register/7e1ec5f1-30ed-4ee7-8cbd-c3436f75306b
Questions:
Justyna.Sikorska@merck.com (Chair)
Bradley.Falk@bms.com (Co-Chair)
Register:
Please register online [ here ] or via e-mail to
Justyna.Sikorska@merck.com (Chair)
Bradley.Falk@bms.com (Co-Chair)
(Past Events)
Jan 22, 2020 – NMR Topical Group Meeting
The North Jersey ACS NMR Topical Group is pleased to presents its March meeting at Princeton, Wednesday, January 22, 2020
Featured Presentation
Speaker: Dr. Bradley Falk, Bristol-Myers Squibb
Title: “Development of a 1H solution NMR platform for characterization, screening, and development of therapeutic proteins and peptides”
Abstract
Simple 1H NMR methods are often underused as a means to characterize protein behavior in discovery and development of Biologics. Most commonly, 1D PROFILE offers a means to assess differences in proteins for batch to batch comparability and biosimilar applications and is the first step in providing a relatively fast, low-resolution option to assess the solution behavior of proteins. We build the next step using DOSY methods to define a Diffusion Profile that defines protein behavior as a distribution of sizes and association states to capture complexities such as self-interactions or aggregation. Lastly we show how coupling information from DOSY and 1H R2 measurements can further refine our understanding of behavior by profiling motions as well as interactions. Combined, these three methods provide an NMR Toolbox that can be used to rapidly characterize behavior, aid in formulation screening and address developability of Biologics under relevant formulation conditions.
Program
6:00 pm Dinner (in Frick Atrium)
7:00 pm Seminar (in Seminar Room A57)
Dinner Cost (pay at the door):
$10 employed, $5 for students, postdoc, retired, unemployed. No charge for seminar only.
Meeting Venue
Frick Chemistry Laboratory
Princeton University
Princeton, NJ 08544
Parking: Parking will be available in Lot 21 (see map link given above under Directions)
Public Transit: It is possible to take NJ Transit all the way to Princeton campus (the symposium location is ~ 10 min walk from the train station). Take the Northeast Corridor NJ transit train to Princeton Junction, then transfer to the small “dinky” train that ends on campus (5 min train ride).
Questions:
Justyna.Sikorska@merck.com (Chair)
or Bradley.Falk@bms.com (Co-Chair)
Register:
Please register online [ here ]
or via e-mail to
Justyna.Sikorska@merck.com
or Bradley.Falk@bms.com
(Past Events)
Nov 21, 2019 – NMR Topical Group Meeting
The North Jersey ACS NMR Topical Group is pleased to presents its March meeting at Rutgers, Thursday, November 21, 2019
Featured Presentation
Speaker: Dr. Christine Jorge, Bristol-Myers Squibb
Authors: Christine Jorge, Janet Caceres-Cortes, Luciano Mueller, Carrie Xu, John Mehl, Thomas Petrone, France Landry, Ying Ren, Michael Reil
Title: “Quantitative NMR of compounds dissolved in multi-component protonated solvents”
Abstract
Proton detected quantitative NMR (qHNMR) is a staple for the determination of analyte concentration in various stages of the drug discovery process. qHNMR remains unprecedented in its high precision, ease of use, non-destructive nature, and simultaneous detection of multiple analytes. Unfortunately, a major limitation results from the difficulty of suppressing protonated solvents thereby largely restricting qHNMR samples to those dissolved in favorable deuterated or biological aqueous solvents where more robust solvent suppression schemes exist. A method was developed that uses band selective optimized flip-angle short-transient (SOFAST) 1D experiments to measure analyte concentration of compounds dissolved in multi-component protonated solvents. When an external reference standard is used, selective excitation of the proton aromatic region (6-10) ppm is sufficient to measure analyte concentration while removing spectral contamination from a wide range of protonated solvents and excipients. Examples are provided which highlight key learnings from routine qHNMR investigations of solutions such as LC-MS/MS standards and animal dosing solutions. The findings presented illustrate how qHNMR can be used to improve the overall quality and reproducibility of experiments in the discovery setting.
Program
6:00 pm Dinner
7:00 pm Seminar
Dinner Cost (pay at the door):
$10 employed / $5 students, postdoc, retired, unemployed. No charge for seminar only.
Meeting Venue
CCB Building (Department of Chemistry and Chemical Biology)
Room 1023
Rutgers, 123 Bevier Rd
Piscataway, NJ 08854
Parking: Parking will be available in LOT 54 (see Directions)
Questions:
Qi.Gao1@merck.com (Chair)
or Justyna.Sikorska@merck.com
Register:
Please register online [ here ] or via e-mail to
Qi.Gao1@merck.com
(Past Events)
Oct 23, 2019 – NMR Symposium
North Jersey ACS NMR Topical Group
presents the
2019 NMR Symposium
October 23rd, 2019
Princeton University Princeton, NJ 08544 [ directions | register ]
* * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * *
Afternoon session (1:00 – 5:15 pm), Frick Chemistry Laboratory
Aalim Weljie
University of Pennsylvania
John Marino
National Institute of
Gregory Walker
Pfizer
Catherine Royer
Rensselaer Polytechnic Institute
Stephen Kadlecek
University of Pennsylvania
Evening Keynote session (5:30 – 6:45 pm)
Arthur Palmer
Columbia University
* * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * *
Dinner (6:45 – 8:00 pm), Frick Laboratory Atrium
$20 employed • $15 postdoc/unemployed/retired
$10 students • No dinner - free
* * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * *
Please register for the meeting and dinner here: [ register ]
* * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * * *
We acknowledge the generous support of our sponsors:














x
(Past Events)
Jun 19, 2019 – NMR Topical Group Meeting
The North Jersey ACS NMR Topical Group is pleased to presents its June meeting at Princeton, Wednesday, June 19, 2019

Bruker Night – Dinner and speakers sponsored by Bruker
Featured Presentations
Anna Codina, PhD
Director, Pharmaceutical Business Unit, Bruker BioSpin

“Bruker News”
Abstract for Anna Codina’s talk
This talk will start by highlighting Bruker’s recent innovative products and solutions. We will then focus on those applications relevant for the pharmaceutical industry, with special emphasis on the study of biologics and biosimilars by magnetic resonance spectroscopy.
Donna Baldisseri, PhD
Senior Applications Scientist, Bruker BioSpin

“Validating Higher Order Structure of Biologics using NMR”
Abstract for Donna Baldisseri’s talk
High-resolution nuclear magnetic resonance (NMR) is a key technology that provides critical information on protein conformation, aggregation, stability, and modifications such as glycosylation. Effectiveness and ease of use in the study of the higher order structure of proteins make this technique a uniquely valuable tool. Recently, new developments in acquisition and data analysis have emerged to establish NMR as a powerful metric for validating the HOS Critical Quality Attribute of the intact molecule utilizing both 1D and 2D NMR methods.
Fast 1D fingerprinting methods will give a quick answer if the biologic is similar to the reference material. To identify changes at the amino acid level, 2D NMR methods are required. An interlaboratory comparison coordinated by NIST (26 labs involved, different magnetic fields, worldwide) demonstrated both high precision and high reproducibility of the 2D methyl fingerprint NMR method. We will show recently developed and optimized acquisition techniques, including excipient signal removal. We will also introduce a newly developed software that allows an optimal workflow for batch to batch analysis of mAb samples. It provides a robust platform for the repeated application of established, tested and, recently developed data evaluation methods, namely: Profile1D (developed by Amgen) and, BiologicsHOS software (developed through the Bruker and Mestrelab strategic collaboration) which includes CCSD (Combined Chemical Shift Deviation), ECHOS (Easy Comparability of Higher Order Structure) and, PCA (Principal Component Analysis) using either the entire spectrum or peaks. We will demonstrate the workflow, and show pros and cons of the different methods.
Program
6:00 pm Dinner (in Frick Atrium)
7:00 pm Seminar (in Seminar Room A57)
Dinner Cost (pay at the door):
$5 for everyone. No charge for seminar only.
Meeting Venue
Frick Chemistry Laboratory
Princeton University
Princeton, NJ 08544
Parking: Parking will be available in Lot 21 (see map link given above under Directions)
Public Transit: It is possible to take NJ Transit all the way to Princeton campus (the symposium location is ~ 10 min walk from the train station). Take the Northeast Corridor NJ transit train to Princeton Junction, then transfer to the small “dinky” train that ends on campus (5 min train ride).
Questions:
qi.gao1@merck.com (Chair) or
justyna.sikorska@merck.com (Co-Chair)
Register:
Please register online here
or via e-mail to
qi.gao1@merck.com (Chair) or
justyna.sikorska@merck.com (Co-Chair)
(Past Events)
Apr 17, 2019 – NMR Topical Group Meeting
The North Jersey ACS NMR Topical Group is pleased to presents its March meeting at Rutgers, Wednesday, April 17, 2019
Featured Presentation
Prof. Brian J. Stockman, PhD, MBA

“NMR-based activity assays to identify and validate fragment leads against two Trichomonas
Abstract
Trichomoniasis is the most prevalent, non-viral sexually transmitted disease in the world. It is caused by the parasitic protozoan, Trichomonas vaginalis, which is incapable of de novo synthesis of purine and pyrimidine rings. Since current 5-nitroimidazole drug treatments show common repeat infections due to increased resistance by the parasite, the development of a novel drug therapy is necessary. Two nucleoside salvage pathway enzymes, adenosine/guanosine nucleoside ribohydrolase and uridine nucleoside ribohydrolase, represent distinct, druggable targets. Inhibition would prevent the production of free nucleobases which the parasite requires. 1H and 19F NMR-based activity assays were used to screen the two enzymes against a 2,000-compound fragment diversity library, resulting in the identification of distinct inhibitor classes. Representative fragments from each structural class were then subjected to two independent counter screens in order to confirm reversible, target-specific inhibition. A ten-fold jump dilution assay proved that the inhibitors were reversible, while the addition of Triton X-100 detergent validated target-specific activity. The NMR-based activity assays were very useful for these counter screens since they provide direct observation of substrate, product, and inhibitor resonances simultaneously. Molecular modeling in combination with structure-activity relationships is being used to guide ongoing medicinal chemistry efforts to discover nM inhibitors of each enzyme for in vitro target validation.
Program
6:00 pm Dinner
7:00 pm Seminar
Dinner Cost (pay at the door):
$15 employed / $10 students, postdoc, retired, unemployed. No charge for seminar only.
Meeting Venue
CABM (Center for Advanced Biotechnology and Medicine)
Room 010
Rutgers, 679 Hoes Lane West
Piscataway, NJ 08854
Parking: Parking will be available in the front of CABM (see map link given above under Directions)
Questions:
Qi.Gao1@merck.com (Chair)
or Justyna.Sikorska@merck.com
Register:
Please register online [ here ] or via e-mail to
Qi.Gao1@merck.com
(Past Events)
Mar 20, 2019 – NMR Topical Group Meeting
The North Jersey ACS NMR Topical Group is pleased to present its March meeting at Princeton, Wednesday, March 20, 2019
Featured Presentation
Prof. Morten Kjærulff Sørensen,
Aarhus University, Denmark

“The Tveskaeg benchtop NMR instrument: Multinuclear, cost-efficient NMR for industry and science“
Abstract
Nuclear magnetic resonance (NMR) is a powerful tool for quantitative molecular analysis. While high-field NMR spectrometers are based on bulky superconducting magnets, several low-field NMR instruments (based on permanent magnets) have been developed as robust, mobile, low-cost alternatives. The vast majority of low-field NMR instruments are limited to 1H experiments sometimes combined with a narrowband channel for another high-sensitive isotope. However, practical applications of NMR exist for a large variety of detection isotopes.
To utilize this potential, we have developed a cost-efficient, benchtop/on-line NMR instrument with a broadband channel covering the frequencies of all relevant NMR-active isotopes with fast digital tune/match capability. The Tveskaeg NMR instrument (NanoNord A/S, Denmark) is based on a ~1.5 T permanent Halbach magnet, a digital console, and a probe with 2 ml sensitive sample volume (i.d. 9.2 mm). The instrument is suitable for use in laboratories, for fieldwork, and in on-line setups for continuous monitoring applications.
Targeting specific industrial applications, we have conducted a variety of studies to demonstrate the performance of the NMR instrumentation in the laboratory and at industrial positions of use. Some of these applications are: (i) On-line monitoring of catalytic fines in heavy fuel oil onboard ships using 27Al NMR. (ii) Continuous monitoring of ammonium, phosphorus and chloride levels at wastewater treatment plants by 14N, 31P and 35Cl NMR. (iii) Quantification of nutrients in agricultural manure by 14N, 17O, 31P and 39K NMR. (iv) Quantification of salt in food products by 23Na and 35Cl NMR. (v) Quantification of protein and fat contents in milk. (vi) Monitoring of boron and lithium in reactor coolant at power plants by 11B, 10B and 7Li NMR.
Furthermore, the benchtop instrument is an efficient spectrometer for wide-line solid-state NMR experiments. The is demonstrated experimentally by acquisition of challenging spectra like the 14N spectrum of KNO3 spanning more than 1 MHz. By introducing interleaved sampling of frequency slices, a highly efficient acquisition is achievable with a sensitivity comparable to high-field NMR experiments.
Overall, our results demonstrate some of the capabilities and the versatility using multinuclear, cost-efficient NMR as a robust analytical tool suitable for both scientific and large-scale industrial applications.
To utilize this potential, we have developed a cost-efficient, benchtop/on-line NMR instrument with a broadband channel covering the frequencies of all relevant NMR-active isotopes with fast digital tune/match capability. The Tveskaeg NMR instrument (NanoNord A/S, Denmark) is based on a ~1.5 T permanent Halbach magnet, a digital console, and a probe with 2 ml sensitive sample volume (i.d. 9.2 mm). The instrument is suitable for use in laboratories, for fieldwork, and in on-line setups for continuous monitoring applications.
Targeting specific industrial applications, we have conducted a variety of studies to demonstrate the performance of the NMR instrumentation in the laboratory and at industrial positions of use. Some of these applications are: (i) On-line monitoring of catalytic fines in heavy fuel oil onboard ships using 27Al NMR. (ii) Continuous monitoring of ammonium, phosphorus and chloride levels at wastewater treatment plants by 14N, 31P and 35Cl NMR. (iii) Quantification of nutrients in agricultural manure by 14N, 17O, 31P and 39K NMR. (iv) Quantification of salt in food products by 23Na and 35Cl NMR. (v) Quantification of protein and fat contents in milk. (vi) Monitoring of boron and lithium in reactor coolant at power plants by 11B, 10B and 7Li NMR.
Furthermore, the benchtop instrument is an efficient spectrometer for wide-line solid-state NMR experiments. The is demonstrated experimentally by acquisition of challenging spectra like the 14N spectrum of KNO3 spanning more than 1 MHz. By introducing interleaved sampling of frequency slices, a highly efficient acquisition is achievable with a sensitivity comparable to high-field NMR experiments.
Overall, our results demonstrate some of the capabilities and the versatility using multinuclear, cost-efficient NMR as a robust analytical tool suitable for both scientific and large-scale industrial applications.
Program
6:00 pm Dinner (in Frick Atrium)
7:00 pm Seminar (in Seminar Room A57)
8:00 pm End
Dinner Cost:
$15 employed / $10 students, postdoc, retired, unemployed. No charge for seminar only.
Meeting Venue
Frick Chemistry Laboratory, Room A57
Princeton University
Princeton, NJ 08544
Parking: Lot 21 (see map link under Directions)
Public Transit: It is possible to take NJ Transit all the way to Princeton campus (the symposium location is ~ 10 min walk from the train station). Take the Northeast Corridor NJ transit train to Princeton Junction, then transfer to the small “dinky” train that ends on campus (5 min train ride).
Questions:
Qi.Gao1@merck.com (Chair) or
Justyna.Sikorska@merck.com (Co-Chair)
Register:
Please register online here
or via e-mail to