North Jersey Section
American Chemical Society

May 16, 2023 – NMR Topical Group Meeting

The North Jersey ACS NMR Topical Group is pleased to present its May meeting online, Tues, May 16, 12:00 noon ET, via Microsoft Teams.


Featured Presentation

Art Edison

Seminar details:

Date: Tuesday May 16 at 12:00 noon ET

Speaker: Art Edison
Professor, University of Georgia, Department of Biochemistry and Chemical Biology, Department of Genetics

Title: “Unique Strengths of NMR Metabolomics: In vivo Metabolism and Improved Compound Identification”

Flyer: [ NJACS-flyer-Art-Edison-MAY2023.pdf ]

Abstract

Metabolomics is an important component of systems biology research in biology and biomedicine. Two major technologies are widely used in metabolomics research, mass spectrometry and NMR spectroscopy. Both have their own strengths and weaknesses. Recently, LC-MS has gained in popularity, thanks largely to its high sensitivity and ability to detect 10s of thousands of features. In this talk, I will highlight some of the unique strengths of NMR metabolomics, most notably approaches to study metabolic dynamics in real-time in cells or microorganisms. We call this continuous in vivo metabolism by NMR (CIVM-NMR). I will also discuss the difficulty that the entire field faces in confident metabolite identification and will present recent approaches to better combine NMR with LC-MS and computational chemistry to improve compound identification.

Judge, M. T., Wu, Y., Tayyari, F., Hattori, A., Glushka, J., Ito, T., Arnold, J., and Edison, A. S. (2019) Continuous in vivo Metabolism by NMR, Front Mol Biosci 6, 26.  

Edison, A. S.; Colonna, M.; Gouveia, G. J.; Holderman, N. R.; Judge, M. T.; Shen, X.; Zhang, S. NMR: Unique Strengths That Enhance Modern Metabolomics Research. (2021) Anal Chem 93 (1), 478-499.

Connection Information

This will be a virtual meeting hosted via Microsoft Teams

The seminar is free of charge. No advance registration is required.

Link to the meeting (uses Microsoft Teams):

https://njacs.org/nmr-meetup

Questions:

Jonathan.OsbornPopp (Chair)
Christine.Jorge@bms.com (Co-Chair)

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