North Jersey Section
American Chemical Society

May 9, 2019 – Spring Symposium and Vendor Exhibition


2019 Spring Symposium & Vendor Exhibition

Sponsored by the

North Jersey ACS Drug Metabolism Discussion Group

“From Small Molecule to Large – Modality Expansion and Impact within Drug Disposition

Date:   May 9, 2019

Time:   8:00 am – 4:00 pm

Venue:  The Palace at Somerset Park,
        333 Davidson Avenue,
        Somerset, NJ 08873     [ directions ]

Registration Information:

  • Pre-registration fee is $125 (pre-register by May 2, 2019).
  • Registration fee at the door is $150 (Checks only)
  • Registration fee is $10 for students and postdocs and $50 for faculty
  • Registration is free for unemployed
Please plan to pre-register as a group, as coordinated by a member of the NJACS DMDG Steering Committee List, below, from your organization.
  • If you have no DMDG member at your company, please contact Elizabeth Joshi ( for registration.
  • Payments by personal or company checks. Sorry, credit cards are not accepted.
  • Checks should be made payable to: NJ Drug Metabolism Discussion Group.



“From Small Molecule to Large – Modality Expansion and Impact within Drug Disposition

 8:00 a.m.

                        Registration / Continental Breakfast / Vendor Exhibit

 9:00 a.m.

Introductory Remarks

Elizabeth Joshi, Chair, NJ DMDG

 9:15 a.m.

The Role of DMPK in Supporting Therapeutic Proteins in a Drug Discovery Setting

Larry Wienkers, PhD, Principal Scientist, Wienkers Consulting

 10:00 a.m.

Applications of Minimal PBPK Models to Understand the Effect of FcRn on Monoclonal Antibody System Persistence

Yanguang (Carter) Cao, Ph.D., Assistant Professor | Division of Pharmacotherapy and Experimental Therapeutics | UNC Eshelman School of Pharmacy

 10:45 a.m.

            Vendor Exhibit & Coffee Break

 11:15 a.m.

Prediction of in vivo molecular stability of protein therapeutics through in vitro assessment of kinetic stability

Kevin Cook, Senior Scientist - PKDM, Amgen

 12:00 p.m.

            Lunch & Vendor Exhibit

 1:15 p.m.

Preclinical PK/TE/PD Approach and Application for First-in-Human Dose Selection of a Therapeutic Antibody Targeting a Checkpoint Receptor

Yanbin Lao, PhD, Principal Research Scientist, Eli Lilly and Company

 2:00 p.m.

Engineered “Smart” Insulin: Insulin-Carbohydrate Conjugates with Responsivity to Physiological Levels of Glucose

SongnianLin , PhD, Director – Discovery Chemistry, Merck Research Laboratories, Kenilworth, NJ

 2:45 p.m.

            Vendor Exhibit & Coffee Break

 3:00 p.m.

Digital nano: Rational Design of Biocompatible Nanomaterials by Virtual Nano Library Techniques and Artificial Intelligence

Hao Zhu, Associate Professor – Chemistry, Rutgers University, New Brunswick, NJ

 3:45 p.m.

                          Program closure


NJ-DMDG Steering Committee 2019-2020
Name Company E-mail address Responsibility
Beth Joshi Merck Chair, 2018-19
Imad Hanna Novartis Chair Elect, 2019-20
Matthew Hoffmann Celgene Treasurer
Naiyu Zheng BMS Vendor Liaison
Manthena Varma Pfizer Past Chair, 2017-18
Bo Wen GSK Past Chair, 2016-17
Lauren Aleksunes Rutgers University Past Chair, 2015-16
Wing Lam Janssen R&D Past Chair, 2013-14
Allen Jones - Past Chair, 2012-13
Anima Ghosal Kean University Member
Ron Kong PTC Therapeutics Member
Lei Tang Sanofi Member
Li Yu Roche Member
Fan Wu Celgene Member
Jin Wu Merck Member
Zhao pie Zeng - Member
Carolina Berthiaume - Member
Maria Markowska - Member


Directions to the Palace at Somerset Park

    333 Davidson Avenue, Somerset, NJ 08873
    Phone: 732-302-9922
    [ website ]
From the New Jersey Turnpike:
    Exit 10 to Interstate 287 North. Follow 10 miles to Exit 10 (527 New Brunswick -- South Bound Brook). Take Easton Ave towards South Bound Brook to first light, make left (Davidson Ave.)
From New York City:
    Lincoln Tunnel to N.J. Turnpike South. Follow N.J. Turnpike directions mentioned above.
From Route 287:
    If traveling north:
      Exit 10 (527 New Brunswick -- South Bound Brook). Follow sign towards Bound Brook, to light make left (Davidson Ave.)
    If traveling south:
      Exit 10 (527 New Brunswick). Left on Easton Ave., to light, make left (Davidson Ave).
From Newark Airport:
    Take NJ Turnpike South to Exit 10 I-287 North to Exit 10 (Easton Ave) at first light, go left on Davidson Ave. Hotel immediately on left.