May 9, 2019 – Spring Symposium and Vendor Exhibition

Program

“From Small Molecule to Large – Modality Expansion and Impact within Drug Disposition”

 8:00 a.m.

                        Registration / Continental Breakfast / Vendor Exhibit

 9:00 a.m.

Introductory Remarks

Elizabeth Joshi, Chair, NJ DMDG

 9:15 a.m.

The Role of DMPK in Supporting Therapeutic Proteins in a Drug Discovery Setting

Larry Wienkers, PhD, Principal Scientist, Wienkers Consulting

 10:00 a.m.

Applications of Minimal PBPK Models to Understand the Effect of FcRn on Monoclonal Antibody System Persistence

Yanguang (Carter) Cao, Ph.D., Assistant Professor | Division of Pharmacotherapy and Experimental Therapeutics | UNC Eshelman School of Pharmacy

 10:45 a.m.

            Vendor Exhibit & Coffee Break

 11:15 a.m.

Prediction of in vivo molecular stability of protein therapeutics through in vitro assessment of kinetic stability

Kevin Cook, Senior Scientist - PKDM, Amgen

 12:00 p.m.

            Lunch & Vendor Exhibit

 1:15 p.m.

Preclinical PK/TE/PD Approach and Application for First-in-Human Dose Selection of a Therapeutic Antibody Targeting a Checkpoint Receptor

Yanbin Lao, PhD, Principal Research Scientist, Eli Lilly and Company

 2:00 p.m.

Engineered “Smart” Insulin: Insulin-Carbohydrate Conjugates with Responsivity to Physiological Levels of Glucose

SongnianLin , PhD, Director – Discovery Chemistry, Merck Research Laboratories, Kenilworth, NJ

 2:45 p.m.

            Vendor Exhibit & Coffee Break

 3:00 p.m.

Digital nano: Rational Design of Biocompatible Nanomaterials by Virtual Nano Library Techniques and Artificial Intelligence

Hao Zhu, Associate Professor – Chemistry, Rutgers University, New Brunswick, NJ

 3:45 p.m.

                          Program closure