The NJ Mass Spectrometry Discussion Group is pleased to announce our April 2019 Monthly Meeting.
NJ MSDG is the second largest mass spectrometry professional association in the nation behind ASMS, with over 1,100 members in the tristate area.
Date: Tuesday April 9, 2019
Venue: Somerville Elks Lodge 1068
375 Union Avenue, Bridgewater, NJ 08807
Please register here. Registration is free, compliments of our sponsor.
5:30 PM Social and Registration
6:15 PM Complimentary Dinner
6:55 PM Welcome and Opening Remarks
7:05 PM Speakers
Speaker 1: Dayanjan S Wijesinghe, Ph.D.
Assistant Professor, Department of Pharmacotherapy and Outcomes Sciences. Director, Laboratory of Pharmacometabolomics and Companion Diagnostics, Virginia Commonwealth University School of Pharmacy
“Lights Out Science: Harnessing advances in computer science to speed up biomedical research”
Speaker 2: Patty Sun
Global Market Manager, Pharma/CRO Quant/Met ID, SCIEX, Framingham MA, USA
“Confident Pharmaceutical Impurity Profiling using High-Res Mass Spec”
Because there can potentially be many impurities, some of which can be toxic and of low abundance, data processing can be onerous and time consuming if the software or the quality and type of data itself is not up to the task. Thus, an automated, high performance solution for detecting and identifying impurities is essential for relieving the burden and efficiently finding any stability or degradation issues.
The SCIEX X500R QTOF system and SCIEX OS Analytics were used to measure stability and detect impurities in amiodarone samples. Amiodarone is an anti-arrhythmic medication used to treat and prevent several types of irregular heartbeats. This integrated hardware and software solution compounds from MS and MS/MS data and reduces the need for manual review.