North Jersey Section
American Chemical Society

Oct 11, 2018 – DMDG FallSymposium and Vendor Exhibition


2018 Fall Symposium & Vendor Exhibition

Sponsored by the

North Jersey ACS Drug Metabolism Discussion Group

“Strategies for Optimizing Pharmacological, Metabolic, and Toxicological Profiles of Clinical Candidates

Date:   October 11, 2018

Time:   8:00 am – 3:45 pm

Venue:  The Palace at Somerset Park,
        333 Davidson Avenue,
        Somerset, NJ 08873     [ directions ]

NJDMDG Fall Symposium 11 Oct 2018

Speakers & Organizers: Bottom row (L to R): Matt Hoffman (Celgene), Beth Joshi (Merck), Laura Armstrong (Rutgers), Piyush Bajaj (Takeda), Judi Wardwell (InSphero), Li Yu (Roche), Top row (L to R): Murat Cirit (MIT), Imad Hanna (Novartis), Naiyu Zheng (BMS), Dan Mudra (Lilly), Wing Lam (Janssen), Fan Wu (Celgene)

Registration Information:

  • Pre-registration fee is $125 (pre-register by October 5, 2018).
  • Registration fee at the door is $150 (Checks only)
  • Registration fee is $10 for students and postdocs and $50 for faculty
  • Registration is free for unemployed
Please plan to pre-register as a group, as coordinated by a member of the NJACS DMDG Steering Committee List, below, from your organization.
  • If you have no DMDG member at your company, please contact Elizabeth Joshi ( for registration.
  • Payments by personal or company checks. Sorry, credit cards are not accepted.
  • Checks should be made payable to: NJ Drug Metabolism Discussion Group.


2009 Fall Symposium and Vendor Exhibition


“Strategies for Optimizing Pharmacological, Metabolic, and Toxicological Profiles of Clinical Candidates”

8:00 a.m.

Registration / Continental Breakfast / Vendor Exhibit

9:00 a.m.

Introductory Remarks

Elizabeth Joshi, Chair, NJ DMDG

9:15 a.m.

Mechanistic Modeling at the Discovery-Development Interface: From Design to Dose

Daniel Mudra, PhD, Director, Discovery ADME, Eli Lilly and Company

10:00 a.m.

Translational DMPK Applications of Tissue Chip Technologies

Murat Cirit, PhD, Director, Translational Center of Tissue Chip Technologies at Massachusetts Institute of Technology (MIT)

10:45 a.m.

Vendor Exhibit & Coffee Break

11:15 a.m.

Microphysiological multi-tissue flow-based system utilizing InSphero 3D InSight™ Microtissues: Applications for DMPK, Drug Metabolism and Drug Discovery

Judi Wardwell, Senior Technical Specialist, InSphero Inc.

12:00 p.m.

Lunch & Vendor Exhibit

1:20 p.m.

Model-informed translational strategies to improve upon drug safety risks

Piyush Bajaj, PhD, Scientist II – Investigative Toxicology, Drug Safety Research and Evaluation, Takeda, Cambridge, MA

2:05 p.m.

Hepatic FXR’s Protective Role Against NASH Development in a High-Fat Diet Induced NAFLD Mouse Model

Laura Armstrong, PhD, Post-Doctoral Research Fellow, Rutgers University

2:35 p.m.

Vendor Exhibit & Coffee Break

3:00 p.m.

Novel Metabolite ID Platform for Therapeutic Proteins

Xiang Yu, PhD, Associate Principle Scientist, PPDM Preclinical ADME Metabolite ID, Merck, West Point, NJ

3:45 p.m.

Program Closure


NJ-DMDG Steering Committee 2018-2019
Name Company E-mail address Responsibility
Beth Joshi Merck Chair, 2018-19
Imad Hanna Novartis Chair Elect, 2019-20
Matthew Hoffmann Celgene Treasurer
Naiyu Zheng BMS Vendor Liaison
Manthena Varma Pfizer Past Chair, 2017-18
Bo Wen GSK Past Chair, 2016-17
Lauren Aleksunes Rutgers University Past Chair, 2015-16
Wing Lam Janssen R&D Past Chair, 2013-14
Allen Jones - Past Chair, 2012-13
Anima Ghosal Kean University Member
Ron Kong PTC Therapeutics Member
Lei Tang Sanofi Member
Li Yu Roche Member
Fan Wu Celgene Member
Jin Wu Merck Member
Zhao pie Zeng - Member
Carolina Berthiaume - Member
Maria Markowska - Member


Directions to the Palace at Somerset Park

    333 Davidson Avenue, Somerset, NJ 08873
    Phone: 732-302-9922
    [ website ]
From the New Jersey Turnpike:
    Exit 10 to Interstate 287 North. Follow 10 miles to Exit 10 (527 New Brunswick — South Bound Brook). Take Easton Ave towards South Bound Brook to first light, make left (Davidson Ave.)
From New York City:
    Lincoln Tunnel to N.J. Turnpike South. Follow N.J. Turnpike directions mentioned above.
From Route 287:
    If traveling north:
      Exit 10 (527 New Brunswick — South Bound Brook). Follow sign towards Bound Brook, to light make left (Davidson Ave.)
    If traveling south:
      Exit 10 (527 New Brunswick). Left on Easton Ave., to light, make left (Davidson Ave).
From Newark Airport:
    Take NJ Turnpike South to Exit 10 I-287 North to Exit 10 (Easton Ave) at first light, go left on Davidson Ave. Hotel immediately on left.