North Jersey Section
American Chemical Society

Apr 20, 2017 – DMDG Spring Symposium and Vendor Exhibition


2017 Spring Symposium & Vendor Exhibition

Sponsored by the

North Jersey ACS Drug Metabolism Discussion Group

“Translating Preclinical Drug Disposition in Clinical Development

Date:    April 20, 2017
Time:    8:00 am – 3:45 pm
Venue:  The Palace at Somerset Park, 333 Davidson Avenue, Somerset, NJ 08873 [ directions ]

Registration Information:

  • Pre-registration fee is $125 (pre-register by April 15, 2017).
  • Registration fee at the door is $150 (Checks only)
  • Registration fee is $10 for students and postdocs and $50 for faculty
  • Registration is free for unemployed

Please plan to pre-register as a group, as coordinated by a member of the NJACS DMDG Steering Committee List, below, from your organization.

  • If you have no DMDG member at your company, please contact Bo Wen ( for registration.
  • Payments by personal or company checks. Sorry, credit cards are not accepted.
  • Checks should be made payable to: NJ Drug Metabolism Discussion Group.


  • Please contact Anima Ghosal ( for information concerning exhibits


“Translating Preclinical Drug Disposition in Clinical Development

8:00 a.m.

Registration / Continental Breakfast / Vendor Exhibit

9:00 a.m.

Introductory Remarks

Bo Wen, Chair, NJ DMDG

9:10 a.m.

Metabolomic and Transcriptomic Analysis of BCRP/Abcg2 and PGP/Abcb1 WT and Double KO Rat Tissues to Identify Endogenous, Dietary and Xenobiotic Substrates

Erin Schuetz, PhD, Member, Department of Pharmaceutical Sciences, St Jude Children’s Research Hospital, Memphis, TN

10:00 a.m.

Assays to Guide the Way at NCATS: Drug Transporters and Drug Efficacy

Matthew Hall, PhD, Biology Group Leader, National Center for Advancing Translational Sciences (NCATS) Chemical Genomics Center, National Institutes of Health, Rockville, MD

10:45 a.m.

Vendor Exhibit & Coffee Break

11:30 p.m.

Emerging Role of Non-P450 Enzymes in Drug Metabolism and Toxicity

Deepak Dalvie, PhD, Sr. Principal Investigator, Department of Drug Metabolism and Pharmacokinetics, Celgene, San Diego, CA

12:15 p.m.

Lunch & Vendor Exhibit

1:45 p.m.

Is it Possible to Accurately Predict the Risk that a Drug Candidate Will Cause Idiosyncratic Drug Reactions?

Jack Uetrecht, PhD, Professor of Pharmacy and Medicine and the Canada Research Chair in Adverse Drug Reactions, University of Toronto, Toronto, Ontario, Canada

2:30 p.m.

Vendor Exhibit & Coffee Break

3:00 p.m.

ADME Analysis of Therapeutic Peptides: Preserving Product Value

Jerome Hochman, PhD, Sr. Principal Scientist, Department of Pharmacokinetics Pharmacodynamics and Drug Metabolism, Merck & Co. West Point, PA

3:45 p.m.

Program Closure


NJ-DMDG Steering Committee 2016-2017
Name Company E-mail address Responsibility
Bo Wen GSK Chair, 2016-17
Manthena Varma Pfizer Chair Elect, 2017-18
Zhao pie Zeng Sanofi Treasurer
Anima Ghosal Kean Univ Vendor Liaison
Lauren Aleksunes Rutgers Univ Past Chair, 2015-16
Richard Tschirret-Guth Merck Past Chair, 2014-15
Wing Lam Janssen R&D Past Chair, 2013-14
Allen Jones Past Chair, 2012-13
Lian Zhou BMS Past Chair, 2011-12
Imad Hanna Novartis Member
Ron Kong PTC Therapeutics Member
Lei Tang Sanofi Member
Li Yu Roche Member
Yaofeng Cheng BMS Member
Virna Schuck Novartis Member
Naiyu Zheng BMS Member
Beth Joshi Merck Member
Matthew Hoffmann Celgene Member
Karen H. Dingley Celgene Member
Carolina Berthiaume Member
Maria Markowska Member


Directions to the Palace at Somerset Park

    333 Davidson Avenue, Somerset, NJ 08873
    Phone: 732-302-9922

From the New Jersey Turnpike:

    Exit 10 to Interstate 287 North.
    Follow 10 miles to Exit 10 (527 New Brunswick -- South Bound Brook).
    Take Easton Ave towards South Bound Brook to first light,
    make left (Davidson Ave.)

From New York City:

    Lincoln Tunnel to N.J. Turnpike South.
    Follow N.J. Turnpike directions mentioned above.

From Route 287:

    If traveling north:

      Exit 10 (527 New Brunswick -- South Bound Brook).
      Follow sign towards Bound Brook, to light
      make left (Davidson Ave.)
    If traveling south:

      Exit 10 (527 New Brunswick).
      Left on Easton Ave., to light,
      make left (Davidson Ave).

From Newark Airport:

    Take NJ Turnpike South to Exit 10
    I-287 North to Exit 10 (Easton Ave)
    at first light, go left on Davidson Ave.
    Hotel immediately on left.