North Jersey Section
American Chemical Society

2009 DMDG Fall Symposium and Vendor Exhibition

“Transporters, Current Industry Practices, and Biologics”

Somerset Crowne Plaza Hotel
110 Davidson Avenue
Somerset, New Jersey

October 14, 2009
8:00 am – 3:30 pm


08:00 am
Registration / Continental Breakfast / Vendor Exhibit

08:50 am
Introductory Remarks
Dr. Philip Krieter, Chair, NJ-DMDG

09:00 am
The Challenges of Designing Cyclic Prodrugs of Opioid Peptides that Permeate the Intestinal Mucosa and the Blood-Brain Barrier [slides (PDF)]
Dr. Ron Borchardt, Solon E. Summerfield Distinguished Professor, Department of Pharmaceutical Chemistry, School of Pharmacy, University of Kansas

09:50 am
In Vitro and In Vivo Induction of Cytochrome P450: A Survey of the Current Practices and Recommendations: A Pharmaceutical Research and Manufacturers of American Perspective [slides (PDF)]
Dr. Gondi Kumar, Senior Director, Department of Drug Metabolism and Pharmacokinetics, Celgene Corporation

10:45 am
Vendor Exhibit & Coffee Break

11:15 am
Inactivation Studies for Predicting Drug-Drug Interactions. Pharmaceutical Industry Recommendations and Recent Observations [slides (PDF)]
Dr. R. Scott Obach, Senior Research Fellow, Biotransformation Group, Pharmacokinetics, Dynamics and Drug Metabolism Department, Pfizer, Inc.

12:00 Nn
Lunch & Vendor Exhibit

01:30 pm
Pharmacokinetic Based Drug-Drug Interactions of Biologicals. Science and Development Strategies [slides (PDF)]
Dr. Frank-Peter Theil, Associate Director, Genentech, Inc.

02:15 pm
Vendor Exhibit & Coffee Break

02:45 pm
PK/PD Study Strategies for Biopharmaceuticals: Is Bigger Better? [slides (PDF)]
Dr. Sharon A. Baughman, Biotechnology Consulting

03:30 pm
Program Closure