“Transporters, Current Industry Practices, and Biologics”
Somerset Crowne Plaza Hotel
110 Davidson Avenue
Somerset, New Jersey
October 14, 2009
8:00 am – 3:30 pm
Program
08:00 am
Registration / Continental Breakfast / Vendor Exhibit
08:50 am
Introductory Remarks
Dr. Philip Krieter, Chair, NJ-DMDG
09:00 am
The Challenges of Designing Cyclic Prodrugs of Opioid Peptides that Permeate the Intestinal Mucosa and the Blood-Brain Barrier [slides (PDF)]
Dr. Ron Borchardt, Solon E. Summerfield Distinguished Professor, Department of Pharmaceutical Chemistry, School of Pharmacy, University of Kansas
09:50 am
In Vitro and In Vivo Induction of Cytochrome P450: A Survey of the Current Practices and Recommendations: A Pharmaceutical Research and Manufacturers of American Perspective [slides (PDF)]
Dr. Gondi Kumar, Senior Director, Department of Drug Metabolism and Pharmacokinetics, Celgene Corporation
10:45 am
Vendor Exhibit & Coffee Break
11:15 am
Inactivation Studies for Predicting Drug-Drug Interactions. Pharmaceutical Industry Recommendations and Recent Observations [slides (PDF)]
Dr. R. Scott Obach, Senior Research Fellow, Biotransformation Group, Pharmacokinetics, Dynamics and Drug Metabolism Department, Pfizer, Inc.
12:00 Nn
Lunch & Vendor Exhibit
01:30 pm
Pharmacokinetic Based Drug-Drug Interactions of Biologicals. Science and Development Strategies [slides (PDF)]
Dr. Frank-Peter Theil, Associate Director, Genentech, Inc.
02:15 pm
Vendor Exhibit & Coffee Break
02:45 pm
PK/PD Study Strategies for Biopharmaceuticals: Is Bigger Better? [slides (PDF)]
Dr. Sharon A. Baughman, Biotechnology Consulting
03:30 pm
Program Closure
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