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Oct 17, 2013 – DMDG Fall Symposium and Vendor Show
Drug Met Symposium and Vendor Show
Date: October 17, 2013
Venue: The Palace at Somerset Park, 333 Davidson Avenue, Somerset, NJ 08873.
2013
Fall Symposium and Vendor Exhibition
Sponsored by the
Drug Metabolism Discussion Group
“Biomarkers, Reactive
Metabolites, Idiosyncratic Reactions”
The Palace at Somerset Park
333 Davidson Avenue
Somerset, New Jersey 08873
17 October, 2013
8:00 am – 3:45 pm
Program |
|
“Biomarkers, Reactive
Metabolites, Idiosyncratic Reactions” |
|
8:00 a.m. |
Registration / Continental Breakfast / Vendor Exhibit |
9:00 a.m. |
Introductory
Remarks Dr. Wing Lam, Chair, NJDMDG |
9:10 a.m. |
Exploring the Mechanism of Metabolic Intermediate
Complex-Based Metabolism-Dependent CYP Inhibition: the Case of Lapatinib Joanna
Barbara, Ph.D., Director of Analytical Services, XenoTech, Lenexa, KS |
10:00 a.m. |
Altered
Drug Metabolism During Pregnancy Hyunyoung
(Young) Jeong, Pharm.D., Ph.D.,
Associate Professor, Department of Pharmacy
Practice and Biopharmaceutical Sciences,
University of Illinois at Chicago, Chicago, IL |
10:45 a.m. |
Vendor Exhibit & Coffee Break |
11:30 p.m. |
Molecular
Imaging Biomarkers for Predicting Treatment Response Paul D. Acton, Ph.D., Scientific
Director & Janssen Fellow, Global Head, Molecular Imaging, Janssen
Research and Development, Spring House, PA |
12:15 p.m. |
Lunch & Vendor Exhibit |
1:45 p.m. |
Why are
Idiosyncratic Drug Reactions Idiosyncratic
Jack Uetrecht, M.D., Ph.D., Professor of Pharmacy and Medicine, University
of Toronto, Toronto, ON |
2:30 p.m. |
Vendor Exhibit & Coffee Break |
3:00 p.m. |
Coadministration of Ritonavir
(RTV) with the HCV Protease Inhibitor Danoprevir
(DNV) Substantially Reduces Reactive Metabolite Formation: In Vitro and In Vivo
Data Bonnie
Brennan , Pharm.D.,
Senior Principal Scientist, Department of Clinical Pharmacology at Roche,
Nutley, NJ |
3:45 p.m. |
Program Closure |
NJ-DMDG Steering Committee 2013-2014:
Name |
Company |
E-mail address |
Role |
Wing
Lam |
Janssen
R&D |
Chair, 2013-14 |
|
Philip
Krieter |
Warner
Chilcott |
Treasurer |
|
Matthew Hoffmann |
Celgene |
mjhoffman@celgene.com |
Vice-Treasurer |
Karen
H. Dingley |
Merck
Research |
Vendor Liaison |
|
Allen
Jones |
Roche
|
Past Chair, 2012-13 |
|
Lian Zhou |
BMS
|
Past Chair, 2011-12 |
|
Imad
Hanna |
Novartis
|
Past Chair, 2010-11 |
|
Roseann Affinito |
KCAS Bio |
Member |
|
Lauren
Aleksunes |
Rutgers
University |
Member |
|
Shiying
Chen |
Merck
Research |
Member |
|
Karl
Frank |
Roche
|
Member |
|
Rong Kong |
PTC Therapeutics |
Member |
|
Maria
Markowska |
Janssen
R&D |
Member |
|
Zhao
pie Zeng |
Sanofi-aventis |
Member |
|
Lei
Tang |
Sanofi-aventis |
Member |
|
Richard
Tschirret-Guth |
Merck
Research |
Member |
|
Bo
Wen |
GSK
|
bo.1.wen@gsk.com |
Member |
Manthena
Varma |
Pfizer
|
Member |
|
Li
Yu |
Roche |
li.yu.ly1@roche.com |
Member |
Yaofeng Cheng |
BMS |
Yaofeng.Cheng@bms.com |
Member |
Carolina Cabral |
|
Member |
Registration:
Pre-registration fee is $125 (pre-register by 10 October 2013).
Registration is Free for
students and unemployed (with proper
identification).
Registration fee at the door is $150 (Checks only).
•
Please plan to pre-register as a
group, as
coordinated by a member of the NJACS DMDG steering committee from your
organization (see list above).
•
If
you have no DMDG member at your company, please contact Wing Lam (mwlam@its.jnj.com)
for registration.
•
Payments
by personal or company checks. Sorry,
credit cards are not accepted.
•
Checks
should be made payable to: NJ Drug Metabolism Discussion Group.
•
Please
also visit our website: http://www.njacs.org/topical-groups/drug-metabolism
Exhibitors:
• Please contact Karen Dingley (karen_dingley@merck.com) for information concerning exhibits
Directions
to the Palace at SomersetPark
333
Davidson Avenue, Somerset,
NJ 08873 08873
[ website
]
Phone: 732-302-9922
From the New Jersey Turnpike:
Exit 10 to
Interstate 287 North. Follow 10 miles to Exit 10 (527
New Brunswick-South Bound Brook). Easton
Ave towards South Bound Brook to first light, make left (Davidson Ave.)
From New York City:
Lincoln Tunnel to
N.J. Turnpike South. Follow N.J. Turnpike directions
mentioned above.
From Route 287:
If traveling north:
Exit 10 (527 New Brunswick-South
Bound Brook). Follow sign towards Bound
Brook, to light make left (Davidson Ave.)
If traveling south:
Exit 10 (527 New
Brunswick). Left on Easton Ave., to light, make left
(Davidson Ave).
From the Newark Airport
Take NJ
Turnpike South to Exit 10- I-287 North to Exit 10 (Easton Ave) to first light, go left on Davidson Ave. Hotel immediately on left.
(Past Events)
Apr 18, 2013 – DMDG Spring Symposium & Vendor Show
“Models, Pharmacogenomics, Pharmacokinetics”
Venue: Hotel Somerset Bridgewater (formerly Crowne Plaza, formerly Somerset Plaza), 110 Davidson Avenue, Somerset, NJ 08873.
Exhibitor Info
Please contact Karen Dingley at karen_dingley@merck.com for information concerning exhibits.
Program [ program book
]

08:00 am — Registration / Continental Breakfast / Vendor Exhibit
09:00 am
Introductory Remarks
Dr. Allen Jones, Chair, NJDMDG
09:10 am
“Novel Hepatic Model Systems for Investigating Mechanisms of Drug-Induced
Liver Injury (DIU)”
Edward L. LeCluyse, Ph.D. , Associate Investigator Institute for Chemical Safety Sciences The Hamner Institutes for Health Sciences, Research Triangle Park, NC
10:00 am
“Pharmacogenomics in American Indian Populations”
Erica L. Woodahl, Ph.D. , Associate Professor Department of Biomedical and Pharmaceutical Sciences University of Montana, MT ]
10:45 am — Vendor Exhibit & Coffee Break
11:30 am
“Pharmacokinetics of Proteins and Peptides”
Joseph P. Balthasar, Ph.D. , Professor of Pharmaceutical Sciences, State University of New York at Buffalo, Buffalo, NY
12:15 pm — Lunch & Vendor Exhibit
1:45 pm
“Glucuronidation, sulfation, and pharmacokinetics of conjugated metabolite”
Swati Nagar, Ph.D. , Associate Professor, Temple University School of Pharmacy, Philadelphia, PA ]
2:30 pm — Vendor Exhibit & Coffee Break
3:00 pm
“A panel of translational xenoreceptor, cytochrome P450, transporter and transplanted liver humanized mouse models for improved prediction of drug responses in Man”
Nico Scheer, Ph.D., Head of the tADMETTM portfolio, Taconic Farms, Inc., Cranbury, NJ ]
3:45 pm — Program Closure
Directions to the Hotel Somerset Bridgewater
Hotel Somerset Bridgewater was formerly Crowne Plaza, formerly Somerset Plaza
110 Davidson Avenue, Somerset, NJ 08873
Phone: 732-560-0500
- From the New Jersey Turnpike:
Exit 10 to Interstate 287 North. Follow 10 miles to Exit 10 (527 New Brunswick-South Bound Brook). Easton Ave towards South Bound Brook to first light, make left (Davidson Ave.) - From New York City:
Lincoln Tunnel to N.J. Turnpike South. Follow N.J. Turnpike directions mentioned above. - From Route 287:
- If traveling north: Exit 10 (527 New Brunswick-South Bound Brook). Follow sign towards Bound Brook, to light make left (Davidson Ave.)
- If traveling south: Exit 10 (527 New Brunswick). Left on Easton Ave., to light, make left (Davidson Ave).
- From the Newark Airport
Take NJ Turnpike South to Exit 10- I-287 North to Exit 10 (Easton Ave) to first light, go left on Davidson Ave. Hotel immediately on left.
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