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Drug Metabolism Discussion Group Events
Welcome to the North Jersey ACS Drug Metabolism Discussion Group events page. Below you'll find a list of upcoming and past events.
(Past Events)
Apr 30, 2020 – DMDG Spring Symposium and Vendor Exhibition
Sponsored by the
North Jersey ACS Drug Metabolism Discussion Group
“Novel Drug Delivery Approaches”
[ program ]
NOTICE: This symposium is postponed to Sept 10 (tentative date).
In light of the evolving situation with the COVID-19 viral outbreak in the US and the world, it is with the deepest regret that we make the difficult decision to postpone the Spring Symposium to September 10, 2020 (tentative date). Besides our concern for the health of our participants, many local companies, vendors and contract research organizations have issued travel guidelines that restrict or prohibit associates from attending conferences, which would greatly limit the size of the audience at the meeting in April.
Imad Hanna
NJ-DMDG chair
Date: April 30, 2020
Time: 8:00 am – 4:00 pm
Venue: The Palace at Somerset Park,
333 Davidson Avenue,
Somerset, NJ 08873
Registration Information:
- Pre-registration fee is $125 (pre-register by April 23, 2020).
- Registration fee at the door is $150 (Checks only)
- Registration fee is $10 for students and postdocs and $50 for faculty
- Registration is free for unemployed
Please plan to pre-register as a group, as coordinated by a member of the NJACS DMDG
- If you have no DMDG member at your company, please contact Elizabeth Joshi (elizabeth.joshi@merck.com) for registration.
- Payments by personal or company checks. Sorry, credit cards are not accepted.
- Checks should be made payable to: NJ Drug Metabolism Discussion Group.
Exhibitors:
- Please contact Naiyu Zheng (naiyu.zheng@bms.com) for information concerning exhibits
Program “Novel Drug Delivery Approaches” |
|
8:00 a.m. | Registration / Continental Breakfast / Vendor Exhibit |
9:00 a.m. | Introductory Remarks Imad Hanna, Chair, NJ DMDG |
9:15 a.m. | SiRNA delivery of GalNac-conjugated molecules Diane Ramsden, Principal Scientist, Alnylam, Cambridge, MA |
10:00 a.m. | Cell-selective prodrugs for molecular targeted drug delivery John Isbell, PhD, Director, Drug Metabolism and Disposition. Genomics Institute of the Novartis Research Foundation, San Diego, CA |
10:45 a.m. | Vendor Exhibit & Coffee Break |
11:15 a.m. | Stem cell-directed targeted enzyme/prodrug therapy of cancer Arash Hatefi, Associate Professor, Department of Pharmaceutics, Rutgers, The State University of New Jersey. |
12:00 p.m. | Lunch & Vendor Exhibit |
1:15 p.m. | Nano particle drug conjugates for efficient delivery to biological targets Liang Zhao, PhD, |
2:00 p.m. | Pharmacokinetic modeling of CNS disposition of 5-HT3 receptor antagonist with quantitative assessment of the role of P-glycoprotein efflux Manting Chiang, PhD, Graduate Student, Pharmaceutical Sciences, Rutgers, The State University of New Jersey. Current affiliation: Clinical Pharmacology & Pharmacometrics, Bristol Meyers Squibb, Princeton, NJ |
2:45 p.m. | Vendor Exhibit & Coffee Break |
3:00 p.m. | Biopharmaceutical characteristics John Morrison, PhD, Pharmaceutical Candidate Optimization, Bristol Meyers Squibb, |
3:45 p.m. | Program closure |
Name | Company | E-mail address | Responsibility |
---|---|---|---|
Imad Hanna | Novartis | imad.hanna@novartis.com | Chair (2019-2020) |
Beth Joshi | Merck | elizabeth.joshi@merck.com | Past Chair (2018-2019) |
Manthena Varma | Pfizer | Manthena.V.Varma@pfizer.com | Past Chair, 2017-18 |
Matthew Hoffmann | Celgene | mjhoffman@celgene.com | Treasurer |
Naiyu Zheng | BMS | naiyu.zheng@bms.com | Vendor Liaison (2018-2020) |
Anima Ghosal | Kean University | ghosala@aol.com | Vendor Liaison |
Bo Wen | GSK | bo.1.wen@gsk.com | Past Chair, 2016-17 |
Lauren Aleksunes | Rutgers University | aleksunes@eohsi.rutgers.edu | Past Chair, 2015-16 |
Carlo Sensenhauser | Janssen R&D | CSensenh@its.JnJ.com | Member |
Allen Jones | Students 2 Science | allen.n.jones@verizon.net | Member |
Ron Kong | PTC Therapeutics | rkong@ptcbio.com | Member |
Lei Tang | Sanofi | Lei.Tang@sanofi.com | Member |
Li Yu | Roche | li.yu.ly1@roche.com | Member |
Maria Markowska | Mmaryla5@yahoo.com | Member | |
Fan Wu | Celgene | fwu@celgene.com | Member |
Hong Shen | BMS | hong.shen1@bms.com | Member |
Directions to the Palace at Somerset Park
-
333 Davidson Avenue, Somerset, NJ 08873
Phone: 732-302-9922
From the New Jersey Turnpike:
-
Exit 10 to Interstate 287 North.
Follow 10 miles to Exit 10 (527 New Brunswick -- South Bound Brook).
Take Easton Ave towards South Bound Brook to first light.
Make left (Davidson Ave).
From New York City:
-
Lincoln Tunnel to N.J. Turnpike South.
Follow N.J. Turnpike directions mentioned above.
From Route 287:
-
If traveling north:
-
Exit 10 (527 New Brunswick -- South Bound Brook)
Follow sign towards Bound Brook, to light.
Make left (Davidson Ave).
If traveling south:
-
Exit 10 (527 New Brunswick).
Left on Easton Ave., to light.
Make left (Davidson Ave).
From Newark Airport:
-
Take NJ Turnpike South to Exit 10
I-287 North to Exit 10 (Easton Ave).
At first light, go left on Davidson Ave.
Hotel immediately on left.
(Past Events)
May 9, 2019 – Spring Symposium and Vendor Exhibition

2019 Spring Symposium & Vendor Exhibition
Sponsored by the
North Jersey ACS Drug Metabolism Discussion Group
“From Small Molecule to Large – Modality Expansion and Impact within Drug Disposition ”
Date: May 9, 2019
Time: 8:00 am – 4:00 pm
Venue: The Palace at Somerset Park,
333 Davidson Avenue,
Somerset, NJ 08873
Registration Information:
- Pre-registration fee is $125 (pre-register by May 2, 2019).
- Registration fee at the door is $150 (Checks only)
- Registration fee is $10 for students and postdocs and $50 for faculty
- Registration is free for unemployed
- If you have no DMDG member at your company, please contact Elizabeth Joshi (elizabeth.joshi@merck.com) for registration.
- Payments by personal or company checks. Sorry, credit cards are not accepted.
- Checks should be made payable to: NJ Drug Metabolism Discussion Group.
Exhibitors:
- Please contact Naiyu Zheng (naiyu.zheng@bms.com) for information concerning exhibits
Program “From Small Molecule to Large – Modality | |
8:00 a.m. |
Registration / Continental Breakfast / Vendor
Exhibit |
9:00 a.m. |
Introductory
Remarks |
9:15 a.m. |
The Role of
DMPK in Supporting Therapeutic Proteins in a Drug Discovery Setting |
10:00 a.m. |
Applications of Minimal PBPK Models to
Understand the Effect of FcRn on Monoclonal |
10:45 a.m. |
|
11:15 a.m. |
Prediction of in vivo
molecular stability of protein therapeutics through in vitro assessment of
kinetic stability |
12:00 p.m. |
|
1:15 p.m. |
Preclinical PK/TE/PD Approach and Application
for First-in-Human Dose Selection of a Therapeutic Antibody Targeting a
Checkpoint Receptor |
2:00 p.m. |
Engineered “Smart” Insulin:
Insulin-Carbohydrate Conjugates with Responsivity to Physiological Levels of
Glucose SongnianLin , PhD, Director – Discovery Chemistry, Merck Research Laboratories,
Kenilworth, NJ |
2:45 p.m. |
|
3:00 p.m. |
Digital nano: Rational
Design of Biocompatible Nanomaterials by Virtual Nano Library Techniques and
Artificial Intelligence |
3:45 p.m. |
Program closure |
Name | Company | E-mail address | Responsibility |
---|---|---|---|
Beth Joshi | Merck | elizabeth.joshi@merck.com | Chair, 2018-19 |
Imad Hanna | Novartis | imad.hanna@novartis.com | Chair Elect, 2019-20 |
Matthew Hoffmann | Celgene | mjhoffman@celgene.com | Treasurer |
Naiyu Zheng | BMS | naiyu.zheng@bms.com | Vendor Liaison |
Manthena Varma | Pfizer | Manthena.V.Varma@pfizer.com | Past Chair, 2017-18 |
Bo Wen | GSK | bo.1.wen@gsk.com | Past Chair, 2016-17 |
Lauren Aleksunes | Rutgers University | aleksunes@eohsi.rutgers.edu | Past Chair, 2015-16 |
Wing Lam | Janssen R&D | wlam@its.JnJ.com | Past Chair, 2013-14 |
Allen Jones | - | allen.n.jones@verizon.net | Past Chair, 2012-13 |
Anima Ghosal | Kean University | ghosala@aol.com | Member |
Ron Kong | PTC Therapeutics | rkong@ptcbio.com | Member |
Lei Tang | Sanofi | Lei.Tang@sanofi.com | Member |
Li Yu | Roche | li.yu.ly1@roche.com | Member |
Fan Wu | Celgene | fwu@celgene.com | Member |
Jin Wu | Merck | Jin_wu@merck.com | Member |
Zhao pie Zeng | - | zhaopiezeng@gmail.com | Member |
Carolina Berthiaume | - | carolina.berthiaume@gmail.com | Member |
Maria Markowska | - | Mmaryla5@yahoo.com | Member |
Directions to the Palace at Somerset Park
- 333 Davidson Avenue, Somerset, NJ 08873
Phone: 732-302-9922
- Exit 10 to Interstate 287 North.
Follow 10 miles to Exit 10 (527 New Brunswick -- South Bound Brook).
Take Easton Ave towards South Bound Brook to first light,
make left (Davidson Ave.)
- Lincoln Tunnel to N.J. Turnpike South.
Follow N.J. Turnpike directions mentioned above.
- If traveling north:
- Exit 10 (527 New Brunswick -- South Bound Brook).
Follow sign towards Bound Brook, to light
make left (Davidson Ave.)
- If traveling south:
- Exit 10 (527 New Brunswick).
Left on Easton Ave., to light,
make left (Davidson Ave).
- Take NJ Turnpike South to Exit 10
I-287 North to Exit 10 (Easton Ave)
at first light, go left on Davidson Ave.
Hotel immediately on left.
(Past Events)
Oct 11, 2018 – DMDG FallSymposium and Vendor Exhibition

2018 Fall Symposium & Vendor Exhibition
Sponsored by the
North Jersey ACS Drug Metabolism Discussion Group
“Strategies for Optimizing Pharmacological, Metabolic, and Toxicological Profiles of Clinical Candidates ”
Date: October 11, 2018
Time: 8:00 am – 3:45 pm
Venue: The Palace at Somerset Park,
333 Davidson Avenue,
Somerset, NJ 08873

Speakers & Organizers: Bottom row (L to R): Matt Hoffman (Celgene), Beth Joshi (Merck), Laura Armstrong (Rutgers), Piyush Bajaj (Takeda), Judi Wardwell (InSphero), Li Yu (Roche), Top row (L to R): Murat Cirit (MIT), Imad Hanna (Novartis), Naiyu Zheng (BMS), Dan Mudra (Lilly), Wing Lam (Janssen), Fan Wu (Celgene)
Registration Information:
- Pre-registration fee is $125 (pre-register by October 5, 2018).
- Registration fee at the door is $150 (Checks only)
- Registration fee is $10 for students and postdocs and $50 for faculty
- Registration is free for unemployed
- If you have no DMDG member at your company, please contact Elizabeth Joshi (elizabeth.joshi@merck.com) for registration.
- Payments by personal or company checks. Sorry, credit cards are not accepted.
- Checks should be made payable to: NJ Drug Metabolism Discussion Group.
Exhibitors:
- Please contact Naiyu Zheng (naiyu.zheng@bms.com) for information concerning exhibits
Program “Strategies for Optimizing Pharmacological, Metabolic, and Toxicological Profiles of Clinical Candidates” |
|
8:00 a.m. |
Registration / Continental Breakfast / Vendor Exhibit |
9:00 a.m. |
Introductory Remarks Elizabeth Joshi, Chair, NJ DMDG |
9:15 a.m. |
Mechanistic Modeling at the Discovery-Development Interface: From Design to Dose Daniel Mudra, PhD, Director, Discovery ADME, Eli Lilly and Company |
10:00 a.m. |
Translational DMPK Applications of Tissue Chip Technologies Murat Cirit, PhD, Director, Translational Center of Tissue Chip Technologies at Massachusetts Institute of Technology (MIT) |
|
Vendor Exhibit & Coffee Break |
11:15 a.m. |
Microphysiological multi-tissue flow-based system utilizing InSphero 3D InSight™ Microtissues: Applications for DMPK, Drug Metabolism and Drug Discovery Judi Wardwell, Senior Technical Specialist, InSphero Inc. |
|
Lunch & Vendor Exhibit |
1:20 p.m. |
Model-informed translational strategies to improve upon drug safety risks Piyush Bajaj, PhD, Scientist II – Investigative Toxicology, Drug Safety Research and Evaluation, Takeda, Cambridge, MA |
2:05 p.m. |
Hepatic FXR’s Protective Role Against NASH Development in a High-Fat Diet Induced NAFLD Mouse Model Laura Armstrong, PhD, Post-Doctoral Research Fellow, Rutgers University |
2:35 p.m. |
Vendor Exhibit & Coffee Break |
3:00 p.m. |
Novel Metabolite ID Platform for Therapeutic Proteins Xiang Yu, PhD, Associate Principle Scientist, PPDM Preclinical ADME Metabolite ID, Merck, West Point, NJ |
3:45 p.m. |
Program Closure |
Name | Company | E-mail address | Responsibility |
---|---|---|---|
Beth Joshi | Merck | elizabeth.joshi@merck.com | Chair, 2018-19 |
Imad Hanna | Novartis | imad.hanna@novartis.com | Chair Elect, 2019-20 |
Matthew Hoffmann | Celgene | mjhoffman@celgene.com | Treasurer |
Naiyu Zheng | BMS | naiyu.zheng@bms.com | Vendor Liaison |
Manthena Varma | Pfizer | Manthena.V.Varma@pfizer.com | Past Chair, 2017-18 |
Bo Wen | GSK | bo.1.wen@gsk.com | Past Chair, 2016-17 |
Lauren Aleksunes | Rutgers University | aleksunes@eohsi.rutgers.edu | Past Chair, 2015-16 |
Wing Lam | Janssen R&D | wlam@its.JnJ.com | Past Chair, 2013-14 |
Allen Jones | - | allen.n.jones@verizon.net | Past Chair, 2012-13 |
Anima Ghosal | Kean University | ghosala@aol.com | Member |
Ron Kong | PTC Therapeutics | rkong@ptcbio.com | Member |
Lei Tang | Sanofi | Lei.Tang@sanofi.com | Member |
Li Yu | Roche | li.yu.ly1@roche.com | Member |
Fan Wu | Celgene | fwu@celgene.com | Member |
Jin Wu | Merck | Jin_wu@merck.com | Member |
Zhao pie Zeng | - | zhaopiezeng@gmail.com | Member |
Carolina Berthiaume | - | carolina.berthiaume@gmail.com | Member |
Maria Markowska | - | Mmaryla5@yahoo.com | Member |
Directions to the Palace at Somerset Park
- 333 Davidson Avenue, Somerset, NJ 08873
Phone: 732-302-9922
- Exit 10 to Interstate 287 North.
Follow 10 miles to Exit 10 (527 New Brunswick — South Bound Brook).
Take Easton Ave towards South Bound Brook to first light,
make left (Davidson Ave.)
- Lincoln Tunnel to N.J. Turnpike South.
Follow N.J. Turnpike directions mentioned above.
- If traveling north:
- Exit 10 (527 New Brunswick — South Bound Brook).
Follow sign towards Bound Brook, to light
make left (Davidson Ave.)
- If traveling south:
- Exit 10 (527 New Brunswick).
Left on Easton Ave., to light,
make left (Davidson Ave).
- Take NJ Turnpike South to Exit 10
I-287 North to Exit 10 (Easton Ave)
at first light, go left on Davidson Ave.
Hotel immediately on left.
(Past Events)
Apr 20, 2017 – DMDG Spring Symposium and Vendor Exhibition
2017 Spring Symposium & Vendor Exhibition
Sponsored by the
North Jersey ACS Drug Metabolism Discussion Group
“Translating Preclinical Drug Disposition in Clinical Development ”
Date: April 20, 2017
Time: 8:00 am – 3:45 pm
Venue: The Palace at Somerset Park, 333 Davidson Avenue, Somerset, NJ 08873
Registration Information:
- Pre-registration fee is $125 (pre-register by April 15, 2017).
- Registration fee at the door is $150 (Checks only)
- Registration fee is $10 for students and postdocs and $50 for faculty
- Registration is free for unemployed
Please plan to pre-register as a group, as coordinated by a member of the NJACS DMDG
- If you have no DMDG member at your company, please contact Bo Wen (bo.1.wen@gsk.com) for registration.
- Payments by personal or company checks. Sorry, credit cards are not accepted.
- Checks should be made payable to: NJ Drug Metabolism Discussion Group.
Exhibitors:
- Please contact Anima Ghosal (ghosala@aol.com) for information concerning exhibits
Program
“Translating Preclinical Drug Disposition
8:00 a.m. Registration / Continental Breakfast / Vendor
Exhibit 9:00 a.m. Introductory
Remarks Bo Wen, Chair, NJ DMDG 9:10 a.m. Metabolomic
and Transcriptomic Analysis of BCRP/Abcg2 and PGP/Abcb1 WT and Double KO Rat
Tissues to Identify Endogenous, Dietary and Xenobiotic Substrates Erin Schuetz,
PhD, Member, Department of Pharmaceutical Sciences, St Jude Children’s
Research Hospital, Memphis, TN 10:00 a.m. Assays to Guide the Way at NCATS: Drug
Transporters and Drug Efficacy Matthew Hall, PhD, Biology Group Leader, National
Center for Advancing Translational Sciences (NCATS) Chemical Genomics Center, National Institutes of
Health, Rockville, MD 10:45 a.m. Vendor
Exhibit & Coffee Break 11:30 p.m. Emerging Role of Non-P450 Enzymes in Drug
Metabolism and Toxicity Deepak Dalvie, PhD, Sr. Principal Investigator, Department of
Drug Metabolism and Pharmacokinetics, Celgene, San Diego, CA 12:15 p.m. Lunch
& Vendor Exhibit 1:45 p.m. Is it Possible to Accurately Predict the Risk
that a Drug Candidate Will Cause Idiosyncratic Drug Reactions? Jack Uetrecht, PhD, Professor
of Pharmacy and Medicine and the Canada Research Chair in Adverse Drug
Reactions, University of Toronto, Toronto, Ontario, Canada 2:30 p.m. Vendor
Exhibit & Coffee Break 3:00 p.m. ADME Analysis of Therapeutic Peptides:
Preserving Product Value Jerome
Hochman, PhD, Sr. Principal Scientist, Department of Pharmacokinetics
Pharmacodynamics and Drug Metabolism, Merck & Co. West Point, PA 3:45 p.m. Program Closure
Name | Company | E-mail address | Responsibility |
---|---|---|---|
Bo Wen | GSK | bo.1.wen@gsk.com | Chair, 2016-17 |
Manthena Varma | Pfizer | Manthena.V.Varma@pfizer.com | Chair Elect, 2017-18 |
Zhao pie Zeng | Sanofi | Zhaopie.Zeng@sanofi-aventis.com | Treasurer |
Anima Ghosal | Kean Univ | ghosala@aol.com | Vendor Liaison |
Lauren Aleksunes | Rutgers Univ | aleksunes@eohsi.rutgers.edu | Past Chair, 2015-16 |
Richard Tschirret-Guth | Merck | richard_tschirretguth@merck.com | Past Chair, 2014-15 |
Wing Lam | Janssen R&D | wlam@its.JnJ.com | Past Chair, 2013-14 |
Allen Jones | allen.n.jones@verizon.net | Past Chair, 2012-13 | |
Lian Zhou | BMS | Lian.zhou@bms.com | Past Chair, 2011-12 |
Imad Hanna | Novartis | imad.hanna@novartis.com | Member |
Ron Kong | PTC Therapeutics | rkong@ptcbio.com | Member |
Lei Tang | Sanofi | Lei.Tang@sanofi-aventis.com | Member |
Li Yu | Roche | li.yu.ly1@roche.com | Member |
Yaofeng Cheng | BMS | Yaofeng.Cheng@bms.com | Member |
Virna Schuck | Novartis | virna.schuck@novartis.com | Member |
Naiyu Zheng | BMS | naiyu.zheng@bms.com | Member |
Beth Joshi | Merck | elizabeth.joshi@merck.com | Member |
Matthew Hoffmann | Celgene | mjhoffman@celgene.com | Member |
Karen H. Dingley | Celgene | kdingley@celgene.com | Member |
Carolina Berthiaume | carolina.berthiaume@gmail.com | Member | |
Maria Markowska | cMmaryla5@yahoo.com | Member |
Directions to the Palace at Somerset Park
- 333 Davidson Avenue, Somerset, NJ 08873
Phone: 732-302-9922
From the New Jersey Turnpike:
- Exit 10 to Interstate 287 North.
Follow 10 miles to Exit 10 (527 New Brunswick -- South Bound Brook).
Take Easton Ave towards South Bound Brook to first light,
make left (Davidson Ave.)
From New York City:
- Lincoln Tunnel to N.J. Turnpike South.
Follow N.J. Turnpike directions mentioned above.
From Route 287:
- If traveling north:
- Exit 10 (527 New Brunswick -- South Bound Brook).
Follow sign towards Bound Brook, to light
make left (Davidson Ave.)
- If traveling south:
- Exit 10 (527 New Brunswick).
Left on Easton Ave., to light,
make left (Davidson Ave).
From Newark Airport:
- Take NJ Turnpike South to Exit 10
I-287 North to Exit 10 (Easton Ave)
at first light, go left on Davidson Ave.
Hotel immediately on left.
(Past Events)
Oct 13, 2016 – DMDG Fall Symposium and Vendor Exhibition
2016 Fall Symposium & Vendor Exhibition
Sponsored by the
North Jersey ACS Drug Metabolism Discussion Group
“Transforming assessment of Drug Disposition with Novel Methodologies”
Date: October 13, 2016
Time: 8:00 am – 3:45 pm
Venue: The Palace at Somerset Park, 333 Davidson Avenue, Somerset, NJ 08873
Registration Information:
- Pre-registration fee is $125 (pre-register by Oct 6, 2016).
- Registration fee at the door is $150 (Checks only)
- Registration fee is $10 for students and postdocs and $50 for faculty
- Registration is free for unemployed
Please plan to pre-register as a group, as coordinated by a member of the NJACS DMDG
- If you have no DMDG member at your company, please contact Bo Wen (bo.1.wen@gsk.com) for registration.
- Payments by personal or company checks. Sorry, credit cards are not accepted.
- Checks should be made payable to: NJ Drug Metabolism Discussion Group.
Exhibitors:
- Please contact Anima Ghosal (ghosala@aol.com) for information concerning exhibits
Program
“Translational Advances in Drug Disposition and Toxicity:
8:00
a.m. Registration
/ Continental Breakfast / Vendor Exhibit 9:00
a.m. Introductory Remarks Bo Wen, Chair, NJ DMDG 9:10
a.m. Predicting Transporter-Based Systemic and Tissue Drug Disposition
Using Quantitative Proteomics and PET Imaging Jashvant Unadkat, PhD, Professor, Department of Pharmaceutics, University of Washington, Seattle,
WA 10:00
a.m. Decoding
Host-Microbe Communication Through Metabolomics Andrew
Patterson, PhD, Associate Professor, Department of Veterinary and Biomedical Sciences, Pennsylvania
State University, University Park, PA 10:45
a.m. Vendor
Exhibit & Coffee Break 11:30
p.m. Drug
Metabolism Enzyme and Transporter Pharmacogenetics
in Drug Development: Industry Practices and Challenges William
Brian, PhD, Senior Director, Department of Translational Medicine and Early
Development (TMED), Sanofi, Bridgewater, NJ
12:15
p.m. Lunch &
Vendor Exhibit
1:45 p.m. Transporter-Mediated
Asymmetric Tissues Disposition for Drug Efficacy and Toxicity: Opportunities
and Challenges in Translation Yurong Lai, PhD, Sr. Principal
Scientist, Department
of Pharmaceutical Candidate Optimization, Bristol-Myers Squibb,
Princeton, NJ 2:30 p.m. Vendor
Exhibit & Coffee Break 3:00
p.m. How
Can The Evolution of LC/MS Technology Enable Drug Metabolism Scientists to
Continue Their Remarkable Contributions to Drug Discovery and Development? Mingshe
Zhu, PhD, Principal Scientist, Department of Biotransformation, Bristol-Myers
Squibb, Princeton, NJ
3:45
p.m. Program Closure
Emerging Technologies and Tools”
Name | Company | E-mail address | Responsibility |
---|---|---|---|
Bo Wen | GSK | bo.1.wen@gsk.com | Chair, 2016-17 |
Manthena Varma | Pfizer | Manthena.V.Varma@pfizer.com | Chair Elect, 2017-18 |
Zhao pie Zeng | Sanofi | Zhaopie.Zeng@sanofi-aventis.com | Treasurer |
Anima Ghosal | Kean Univ | ghosala@aol.com | Vendor Liaison |
Lauren Aleksunes | Rutgers Univ | aleksunes@eohsi.rutgers.edu | Past Chair, 2015-16 |
Richard Tschirret-Guth | Merck | richard_tschirretguth@merck.com | Past Chair, 2014-15 |
Wing Lam | Janssen R&D | wlam@its.JnJ.com | Past Chair, 2013-14 |
Allen Jones | allen.n.jones@verizon.net | Past Chair, 2012-13 | |
Lian Zhou | BMS | Lian.zhou@bms.com | Past Chair, 2011-12 |
Imad Hanna | Novartis | imad.hanna@novartis.com | Member |
Ron Kong | PTC Therapeutics | rkong@ptcbio.com | Member |
Lei Tang | Sanofi | Lei.Tang@sanofi-aventis.com | Member |
Li Yu | Roche | li.yu.ly1@roche.com | Member |
Yaofeng Cheng | BMS | Yaofeng.Cheng@bms.com | Member |
Virna Schuck | Novartis | virna.schuck@novartis.com | Member |
Naiyu Zheng | BMS | naiyu.zheng@bms.com | Member |
Beth Joshi | Merck | elizabeth.joshi@merck.com | Member |
Matthew Hoffmann | Celgene | mjhoffman@celgene.com | Member |
Karen H. Dingley | Celgene | kdingley@celgene.com | Member |
Carolina Berthiaume | carolina.berthiaume@gmail.com | Member | |
Maria Markowska | cMmaryla5@yahoo.com | Member |
Directions to the Palace at Somerset Park
- 333 Davidson Avenue, Somerset, NJ 08873
Phone: 732-302-9922
From the New Jersey Turnpike:
- Exit 10 to Interstate 287 North.
Follow 10 miles to Exit 10 (527 New Brunswick -- South Bound Brook).
Take Easton Ave towards South Bound Brook to first light,
make left (Davidson Ave.)
From New York City:
- Lincoln Tunnel to N.J. Turnpike South.
Follow N.J. Turnpike directions mentioned above.
From Route 287:
- If traveling north:
- Exit 10 (527 New Brunswick -- South Bound Brook).
Follow sign towards Bound Brook, to light
make left (Davidson Ave.)
- If traveling south:
- Exit 10 (527 New Brunswick).
Left on Easton Ave., to light,
make left (Davidson Ave).
From Newark Airport:
- Take NJ Turnpike South to Exit 10
I-287 North to Exit 10 (Easton Ave)
at first light, go left on Davidson Ave.
Hotel immediately on left.
(Past Events)
April 14, 2016 – DMDG Spring Symposium and Vendor Exhibition
Drug Met Symposium and Vendor Show
Venue: The Palace at Somerset Park, 333 Davidson Avenue, Somerset, NJ 08873.
Mark your calendars for The North Jersey Drug Metabolism Discussion Group Spring 2016 Symposium and Vendor Exhibition, to be held at The Palace at Somerset Park, 333 Davidson Avenue, Somerset, NJ 08873, on Thursday, April 14, from 8:00-4:00 PM.
Registration Information:
Pre-registration fee is $125 (pre-register by 7 April 2016).
Registration fee at the door is $150 (Checks only)
Registration fee is $10 for students and postdocs and $50 for faculty
Registration is free for unemployed
Please plan to pre-register as a group, as coordinated by a member of the NJACS DMDG steering committee from your organization (see list).
- If you have no DMDG member at your company, please contact Richard Lauren Aleksunes (aleksunes@eohsi.rutgers.edu) for registration.
- Payments by personal or company checks. Sorry, credit cards are not accepted.
- Checks should be made payable to: NJ Drug Metabolism Discussion Group.
Exhibitors:
- Please contact Karen Dingley (karen_dingley@merck.com) for information concerning exhibits
2016 Spring Symposium and Vendor Exhibition
Sponsored by the
North Jersey ACS
Drug Metabolism Discussion Group
“Transforming assessment of Drug Disposition with Novel Methodologies”
The Palace at Somerset Park, 333 Davidson Avenue Somerset, New Jersey
14 April, 2016 8:00 am – 4:00 pm
Program |
|
“Transforming assessment of Drug Disposition with Novel Methodologies” |
|
8:00 a.m. |
Registration / Continental Breakfast / Vendor Exhibit |
9:00 a.m. |
Introductory Remarks Lauren Aleksunes, Chair, NJDMDG |
9:10 a.m. |
Topic: Application of Engineered Mouse Models for Xenobiotic Disposition Studies Xinxin Ding, SUNY Polytechnic Institute |
10:00 a.m. |
Topic: Challenges in Identifying Biomarkers for Transporter-Mediated Drug-Drug Interactions in Liver and Kidney Raymond Evers, Merck & Co. |
10:45 a.m. |
Vendor Exhibit & Coffee Break |
11:30 p.m. |
Topic: Microsampling in Nonclinical Studies: Where are We Now? Laura Patrone, Bristol-Myers Squibb |
12:15 p.m. |
Lunch & Vendor Exhibit |
1:45 p.m. |
Topic: MALDI Imaging MS: Seeing Drug ADME in Tissues at Last Stephen Castellino, GlaxoSmithKline |
2:30 p.m. |
Vendor Exhibit & Coffee Break |
3:00 p.m. |
Topic: Validation of an Integrated Series of Ligand Binding Assays for the Quantitative Determination of Antibody Drug Conjugates in Biological Matrices Heather Myler, Bristol-Myers Squibb |
3:45 p.m. |
Program Closure |
(Past Events)
October 15, 2015 – DMDG Spring Symposium and Vendor Exhibition
Drug Met Symposium and Vendor Show
Venue: The Palace at Somerset Park, 333 Davidson Avenue, Somerset, NJ 08873.
Mark your calendars for The North Jersey Drug Metabolism Discussion Group Spring 2015 Symposium and Vendor Exhibition, to be held at The Palace at Somerset Park, 333 Davidson Avenue, Somerset, NJ 08873, on Monday, October 15, from 8:00-4:00 PM.
Registration Information:
Pre-registration fee is $125 (pre-register by 15 October 2015).
Registration fee at the door is $150 (Checks only)
Registration fee is $10 for students and postdocs and $50 for faculty
Registration is free for unemployed
Please plan to pre-register as a group, as coordinated by a member of the NJACS DMDG steering committee from your organization (see list).
· If you have no DMDG member at your company, please contact Richard Tschirret-Guth (richard_tschirretguth@merck.com) for registration.
· Payments by personal or company checks. Sorry, credit cards are not accepted.
· Checks should be made payable to: NJ Drug Metabolism Discussion Group.
Exhibitors:
· Please contact Karen Dingley (karen_dingley@merck.com) for information concerning exhibits
2015 Fall Symposium and Vendor Exhibition
Sponsored by the
North Jersey ACS
Drug Metabolism Discussion Group
“Strategies to Predict and Reduce Drug Interactions and Toxicities”
The Palace at Somerset Park 333 Davidson Avenue Somerset, New Jersey 15 October, 2015 8:00 am – 3:45 pm
Program |
|
“Recent Advances in Drug Distribution and Drug Action” |
|
8:00 a.m. |
Registration / Continental Breakfast / Vendor Exhibit |
9:00 a.m. |
Introductory Remarks Richard Tschirret-Guth, Chair, NJDMDG |
9:10 a.m. |
Topic: Identifying Strategies to Prevent Antiretroviral Drug-induced Toxicities Namandje Bumpus, Johns Hopkins School of Medicine |
10:00 a.m. |
Topic: Targeted Pharmacological Control of the Microbiome to Improve Human Health Matthew Redinbo, University of North Carolina at Chapel Hill |
10:45 a.m. |
Vendor Exhibit & Coffee Break |
11:30 p.m. |
Topic: Toxicity Prediction and Development of Pharmacogenetic Co-Diagnostics Using Diversity Outbred Mice Alison Harrill, University of Arkansas for Medical Sciences |
12:15 p.m. |
Lunch & Vendor Exhibit |
1:45 p.m. |
Topic: Renal Drug Interactions: Progress and Challenges in Making Predictions in a Complex System Adrian Ray, Gilead Sciences |
2:30 p.m. |
Vendor Exhibit & Coffee Break |
3:00 p.m. |
Topic: Cynomolgus Monkey as a Potential Model to Assess Drug Interactions involving Hepatic OATP Transporters: In Vitro, In Vivo, and In Vitro-to-In Vivo Extrapolation Hong Shen, Bristol-Myers Squibb |
3:45 p.m. |
Program Closure |
(Past Events)
April 27, 2015 – DMDG Spring Symposium and Vendor Exhibition
Drug Met Symposium and Vendor Show
Venue: The Palace at Somerset Park, 333 Davidson Avenue, Somerset, NJ 08873.
Mark your calendars for The North Jersey Drug Metabolism Discussion Group Spring 2015 Symposium and Vendor Exhibition, to be held at The Palace at Somerset Park, 333 Davidson Avenue, Somerset, NJ 08873, on Monday, April 27, from 8:00-4:00 PM.
Registration Information:
Pre-registration fee is $125 (pre-register by 17 April 2015).
Registration fee at the door is $150 (Checks only)
Registration fee is $10 for students and postdocs and $50 for faculty
Registration is free for unemployed
Please plan to pre-register as a group, as coordinated by a member of the NJACS DMDG steering committee from your organization (see list).
· If you have no DMDG member at your company, please contact Richard Tschirret-Guth (richard_tschirretguth@merck.com) for registration.
· Payments by personal or company checks. Sorry, credit cards are not accepted.
· Checks should be made payable to: NJ Drug Metabolism Discussion Group.
Exhibitors:
· Please contact Karen Dingley (karen_dingley@merck.com) for information concerning exhibits
2015 Spring Symposium and Vendor Exhibition
Sponsored by the
North Jersey ACS
Drug Metabolism Discussion Group
“Recent Advances in Drug Distribution and Drug Action”
The Palace at Somerset Park 333 Davidson Avenue Somerset, New Jersey 27 April, 2015 8:00 am – 3:45 pm
Program |
|
“Recent Advances in Drug Distribution and Drug Action” |
|
8:00 a.m. |
Registration / Continental Breakfast / Vendor Exhibit |
9:00 a.m. |
Introductory Remarks Richard Tschirret-Guth, Chair, NJDMDG |
9:10 a.m. |
Topic: Prediction of unbound intracellular drug concentration in the presence of transporters: from in vitro to in vivo Kenneth Korzekwa, PhD, Associate Professor Department of Pharmaceutical Sciences, School of Pharmacy, Temple University, Philadelphia, PA |
10:00 a.m. |
Topic: Single cell pharmcokinetics Greg Thurber, PhD, Assistant Professor, Department of Chemical Engineering, University of Michigan, Ann Arbor, MI |
10:45 a.m. |
Vendor Exhibit & Coffee Break |
11:30 p.m. |
Topic: Imaging drug distribution and biomarker response in drug discovery Paul J. McCracken, PhD, Director of Imaging, biomarkers and Personalized Medicine CFU, Eisai Product Creation Systems, Andover, MA |
12:15 p.m. |
Lunch & Vendor Exhibit |
1:45 p.m. |
Topic: Biomarkers identification/analysis in clinical research Steven P. Piccoli, Ph.D. Research Fellow, Immunochemistry and Biomarker Development, Bristol-Myers Squibb, Princeton, NJ |
2:30 p.m. |
Vendor Exhibit & Coffee Break |
3:00 p.m. |
Topic: Systems pharmacology approach to drug disposition and action James M. Gallo, PhD, Professor, Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY |
3:45 p.m. |
Program Closure |
(Past Events)
October 13, 2014 – DMDG Fall Symposium and Vendor Exhibition
Drug Met Symposium and Vendor Show
Date: Oct 13, 2014 — 8:00 am – 4:00 pm
Venue: The Palace at Somerset Park, 333 Davidson Avenue, Somerset, NJ 08873.
Mark your calendars for the The North Jersey Drug Metabolism Discussion Group Fall Symposium and Vendor Exhibition, to be held at The Palace at Somerset Park, 333 Davidson Avenue, Somerset, NJ 08873, on Monday, October 13, from 8:00-4:00 PM. Additional details will be posted in September.
Current DMDG Board Members:
Name | Company | Role | |
Richard Tschirret-Guth |
Merck Research |
Chair 2014-15 |
|
Lauren Aleksunes |
Rutgers University |
Chair-elect, 2015-16 |
|
Matthew Hoffmann |
Celgene |
Treasurer |
|
Karen H. Dingley |
Merck Research |
Vendor Liaison |
|
Wing Lam |
Janssen R&D |
Past-Chair, 2013-14 |
|
Allen Jones |
|
Past Chair, 2012-13 |
|
Lian Zhou |
BMS |
Past Chair, 2011-12 |
|
Imad Hanna |
Novartis |
Past Chair, 2010-11 |
|
Roseann Affinito |
KCAS Bio |
Member |
|
Shiying Chen |
Merck Research |
Member |
|
Ron Kong |
PTC Therapeutics |
Member |
|
Maria Markowska |
|
Member |
|
Zhao pie Zeng |
Sanofi-aventis |
Member |
|
Lei Tang |
Sanofi-aventis |
Member |
|
Bo Wen |
GSK |
Member |
|
Manthena Varma |
Pfizer |
Member |
|
Li Yu |
Roche |
Member |
|
Yaofeng Cheng |
BMS |
Member |
|
Carolina Cabral |
|
Member |
(Past Events)
May 1, 2014 – DMDG Spring Symposium and Vendor Exhibition
Drug Met Symposium and Vendor Show
Date: May 1, 2014
Venue: The Palace at Somerset Park, 333 Davidson Avenue, Somerset, NJ 08873.
2014 Spring
Symposium and Vendor Exhibition
Sponsored by the
North
Jersey ACS
Drug
Metabolism Discussion Group
“Effect of gender, hepatic and renal function on the systemic
clearance of small molecules/biotherapeutics and anti-HCV polypharmacy”
The Palace at Somerset Park
333 Davidson Avenue
Somerset, New Jersey
1 May, 2014
8:00 am – 3:45 pm
Program |
|
“Effect of gender, hepatic and renal function on the systemic
clearance of small molecules/biotherapeutics and anti-HCV polypharmacy” |
|
8:00
a.m. |
Registration
/ Continental Breakfast / Vendor Exhibit |
9:00
a.m. |
Introductory Remarks Dr. Wing Lam, Chair,
NJDMDG |
9:10
a.m. |
FXR and Liver Functions
Grace L. Guo, MBBS, PhD,
Associate Professor, Department of Pharmacology and Toxicology, Ernst Mario
School of Pharmacy, the Environmental and Occupational Health Sciences
Institute, Rutgers University, Piscataway, NJ |
10:00
a.m. |
The Clearance of Drugs and Biologics in
Human Models of Kidney Disease Melanie S. Joy, PharmD, PhD, FCCP, FASN, Department of Pharmaceutical
Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University
of Colorado Anschutz Medical Campus, Aurora, CO |
10:45
a.m. |
Vendor Exhibit &
Coffee Break |
11:30
p.m. |
Hypnotic Drugs, Gender, and the FDA
David J. Greenblatt, MD,
Professor of Pharmacology and Experimental Therapeutics, Tufts University
School of Medicine and Tufts Medical Center, |
12:15
p.m. |
Lunch & Vendor Exhibit |
1:45
p.m. |
Quantitative Pharmacology in
Biotherapeutics Development Honghui Zhou, PhD, Senior
Director and Janssen Fellow, Head, Pharmacokinetics and Pharmacodynamics,
Biologics Clinical Pharmacology, Biotechnology CoE,
Janssen Research & Development, LLC., Spring House, PA
|
2:30
p.m. |
Vendor Exhibit &
Coffee Break |
3:00
p.m. |
The Clinical Pharmacology of Anti-HCV
Agents Steven J. Kovacs, PharmD, Director, Translational Medicine, Novartis
Institutes for Biomedical Research , East Hanover, NJ |
3:45
p.m. |
Program Closure |
2013 DMDG Board Members:
Name | Company | Role | |
Wing Lam |
Janssen R&D |
Chair, 2013-14 |
|
Richard Tschirret-Guth |
Merck Research |
Chair-elect 2014-15 |
|
Matthew Hoffmann |
Celgene |
Treasurer |
|
Karen H. Dingley |
Merck Research |
Vendor Liaison |
|
Allen Jones |
Alliance Technologies |
Past Chair, 2012-13 |
|
Lian Zhou |
BMS |
Past Chair, 2011-12 |
|
Imad Hanna |
Novartis |
Past Chair, 2010-11 |
|
Roseann Affinito |
KCAS Bio |
Member |
|
Lauren Aleksunes |
Rutgers University |
Member |
|
Shiying Chen |
Merck Research |
Member |
|
Karl Frank |
|
Member |
|
Ron Kong |
PTC Therapeutics |
Member |
|
Maria Markowska |
|
Member |
|
Zhao pie Zeng |
Sanofi-aventis |
Member |
|
Lei Tang |
Sanofi-aventis |
Member |
|
Richard Tschirret-Guth |
Merck Research |
Member |
|
Bo Wen |
GSK |
Member |
|
Manthena Varma |
Pfizer |
Member |
|
Li Yu |
Roche |
Member |
|
Yaofeng Cheng |
BMS |
Member |
|
Carolina Cabral |
|
Member |
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2021 Baekeland Award
The North Jersey Section of the American Chemical Society will award the 2021 Leo Hendrik Baekeland Award on May 12, 2022, to Dr Prashant K. Jain.
The Section presents the Award biennially to commemorate the technical and industrial achievements of Leo Hendrik Baekeland and to encourage younger chemists to emulate his example.
Message From Justyna Sikorska
It is a great honor to serve as Chair for 2023. I look forward to leading this incredible and diverse group of volunteers . . . My goals for 2023 start with supporting our diverse topical groups and committees in organizing exciting seminars . . .
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