Meeting of the Princeton ACS Section:“1D Lepidocrocite Titania-based Nanomaterials, Their Diverse Morphologies and Exceptional Properties”

Frick Chemistry Laboratory, Taylor Auditorium, Princeton University

Meeting of the Princeton ACS Section Tuesday, March 12, 2024 Professor Michel. W. Barsoum Drexel University, Philadelphia, PA “1D Lepidocrocite Titania-based Nanomaterials, Their Diverse Morphologies and Exceptional Properties” Frick Chemistry Laboratory, Taylor Auditorium, Princeton University Mixer (in Atrium) 6:30 pm; Lecture 7:00 pm   Abstract: Recently, we converted 15 binary and ternary titanium carbides, nitrides, borides, phosphides, and silicides into lepidocrocite-based, one dimensional, 1D, sub-nanometer nanofilaments, NFs, ≈ 5x7 Å in cross-section by reacting them with a tetramethylammonium hydroxide, TMAH, aqueous solution at ≈ 85 °C range for tens of hours. In some cases, the conversion is 100 % precluding the need for centrifuges, filters, etc. We currently routinely make 100 g batches in a lab setting. Depending on with what and the order the reaction products are washed, the 1D NFs self-assemble into loose, spaghetti-shaped fibers, ≈ 30 nm in diameter, fully inorganic TiO2 gels, pseudo 2D or porous mesoscopic particles. In all cases, the fundamental building block is 1D lepidocrocite NFs, ≈ 3 nm long, that self-assemble into the aforementioned morphologies. At this time, we believe that our materials are the only thermodynamically stable 1D NFs in water, with important implications in photo- and chemical catalysis. The production

Executive Committee Meeting

Zoom Meeting

This will be a virtual meeting held on Zoom. If you did not receive a Zoom invite, then register below and you will receive an email with the Zoom connection. Best, Sandra

NJCG: Green Chromatography Webinar

NJCG is hosting an online seminar on Thursday, March 14th, 2024, focused on "Green Chromatography". Register here.  Please find the attached flyer for more information.

NMR Seminar: POKY, The Software Suite for NMR Studies and More

MS Teams

Abstract NMR spectroscopy is a powerful technique for molecular studies. In biomolecular research, it offers a wide range of unique approaches, from analyzing small compounds to investigating macromolecules, and from examining purified samples to studying complex mixtures. NMR analysis is primarily conducted in dry laboratory settings. Once the sample is prepared and inserted into the spectrometer, nearly all processes are performed using computers. When it comes to spectral analysis of biomacromolecules, such as proteins and nucleic acids, Sparky has been the gold standard program for a few decades. Donald Kneller from the Tack Kuntz group and Tom Goddard from the Tom Ferrin group were early contributors to UCSF-Sparky in the 90s. I took over from the University of California, San Francisco (UCSF) and developed NMRFAM-Sparky at the National Magnetic Resonance Facility at Madison (NMRFAM) until 2020 before I moved to the University of Colorado Denver. Since then, my group has developed the new program, POKY. POKY succeeds all the previous capabilities while provides new and enhanced features, leveraging the recent AI revolution. It is highly automated and efficient, covering assignment, peak picking, relaxation, dynamics, metabolomics, and small compound analysis. Additionally, POKY incorporates self-teaching capabilities. We have identified six different challenges,

2024 Spring Symposium and Vendor Exhibition (Drug Metabolism Discussion Group )

The Palace at Somerset Park 333 Davidson Ave, Somerset, NJ, United States

Discovery, Development, and Regulatory Strategy for Biologics and ADCs in Oncology and Immunology Program 8:00 a.m. Registration / Continental Breakfast / Vendor Exhibit 8:45 a.m. Introductory Remarks Arian Emami Riedmaier, PhD; Chair, NJ DMDG 9:00 a.m. The Evolution of First-in-Human Dose Selection for Biologics in Oncology and Beyond Haiqing Wang, PhD; Senior Director, DMPK, Alnylam 9:45 a.m. Mutants, Loners and Bad Influences (Systems Model of KRAS Pathway Describing Mechanism of Response in G13D CRC) Edward Stites, MD, PhD; Associate Professor of Laboratory Medicine and Pathology, Yale School of Medicine 10:30 a.m. Vendor Exhibit & Coffee Break 11:15 a.m. Mitochondrial Bioenergetic Health Index as a Biomarker for Kidney Injury Kiran Deshpande; PhD Candidate, Ernest Mario School of Pharmacy Rutgers, New Brunswick, NJ 11:45 p.m. Vendor Exhibit & Lunch 12:45 p.m. Immunogenicity Risk Assessments and Bioanalytical Strategy for IND Enabling Studies for Complex Biologics Sanjay Dholakiya, PhD; Principal Scientist, BMS 1:30 p.m. Developing Effective Drug Development Strategies for Biologics Samuel Chuang, PhD; Senior Director, Scientific Advisory Services, Charles River 2:15 p.m. Vendor Exhibit & Coffee Break 2:30 p.m. ADCs as Therapeutic Options: History, Resurgence and DXd Based ADCs from DSI Tushar Garimella, PhD; Executive Director, Clinical Pharmacology, Daiichi-Sankyo 3:15 p.m. Medicilon Strategy

Register Now $10.00 – $150.00

2023 Baekeland Award Symposium

Lenfell Hall, Mansion (Hennessy Hall), Fairleigh Dickinson University Florham campus, Madison, NJ 285 Madison Avenue, Madison, NJ, United States

The 2023 Baekeland Award Symposium will be held in honor of Prof. Keary M. Engle (The Scripps Research Institute) on April 12, 2024 at Fairleigh Dickinson University in Madison, New Jersey. Dr. Engle will be celebrated for his novel catalytic alkene functionalization reactions, inventing general and versatile strategies for the programmed functionalization of olefins and developing nickel and palladium catalysts that are widely used in academic and industrial research labs around the world. The speakers of the symposium include Dr. Steven Wisniewski (Bristol-Myers Squibb), Tianning Diao (New York University), Peng Liu (University of Pittsburgh), and Scott Miller (Yale University). Detailed program and agenda to follow. Keary Engle -- Photo by Don Boomer The title of his talk will be "Metal–olefin interactions and the catalytic chemistry they inspire" Abstract & Bio Please see the flyer for the schedule and other information.  Please register on the right. Schedule 1:00  Registration 1:30  Welcome Address Dr. Dorothy J. Phillips, ACS President-Elect Dr. Sandra Keyser, NJ-ACS & Baekeland Symposium Chair 1:45  Dr. Steven Wisniewski How Base Metals Catalysis Can Impact Process Chemistry 2:25  Dr. Tianning Diao Leveraging One- and Two-Electron Mechanisms in Nickel-Catalyzed Cross-Coupling 3:05    Dr. Peng Liu Modeling Catalytic Organic Reactions

Register Now $5.00 – $15.00

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