2018 Fall Symposium & Vendor Exhibition

Sponsored by the

North Jersey ACS Drug Metabolism Discussion Group

“Strategies for Optimizing Pharmacological, Metabolic, and Toxicological Profiles of Clinical Candidates

Date:   October 11, 2018

Time:   8:00 am – 3:45 pm

Venue:  The Palace at Somerset Park,
        333 Davidson Avenue,
        Somerset, NJ 08873     [ directions ]

NJDMDG Fall Symposium 11 Oct 2018

Speakers & Organizers: Bottom row (L to R): Matt Hoffman (Celgene), Beth Joshi (Merck), Laura Armstrong (Rutgers), Piyush Bajaj (Takeda), Judi Wardwell (InSphero), Li Yu (Roche), Top row (L to R): Murat Cirit (MIT), Imad Hanna (Novartis), Naiyu Zheng (BMS), Dan Mudra (Lilly), Wing Lam (Janssen), Fan Wu (Celgene)

Registration Information:

  • Pre-registration fee is $125 (pre-register by October 5, 2018).
  • Registration fee at the door is $150 (Checks only)
  • Registration fee is $10 for students and postdocs and $50 for faculty
  • Registration is free for unemployed

Please plan to pre-register as a group, as coordinated by a member of the NJACS DMDG Steering Committee List, below, from your organization.

  • If you have no DMDG member at your company, please contact Elizabeth Joshi (elizabeth.joshi@merck.com) for registration.
  • Payments by personal or company checks. Sorry, credit cards are not accepted.
  • Checks should be made payable to: NJ Drug Metabolism Discussion Group.



2009 Fall Symposium and Vendor Exhibition


for Optimizing Pharmacological, Metabolic, and Toxicological Profiles of
Clinical Candidates”


/ Continental Breakfast / Vendor Exhibit


Introductory Remarks

Elizabeth Joshi,
Chair, NJ DMDG


Mechanistic Modeling at the Discovery-Development Interface: From Design to Dose

Daniel Mudra,

PhD, Director, Discovery ADME, Eli Lilly and Company


Translational DMPK
Applications of Tissue Chip Technologies

Murat Cirit,
PhD, Director, Translational
Center of Tissue Chip Technologies at Massachusetts Institute of Technology

10:45 a.m.

Vendor Exhibit & Coffee


multi-tissue flow-based system utilizing InSphero 3D InSight™ Microtissues:
Applications for DMPK, Drug Metabolism and Drug Discovery

Judi Wardwell,
Senior Technical
Specialist, InSphero Inc.

12:00 p.m.

Lunch & Vendor Exhibit


translational strategies to improve upon drug safety risks

Piyush Bajaj,
PhD, Scientist II
– Investigative Toxicology, Drug Safety Research and Evaluation,

Takeda, Cambridge, MA

2:05 p.m.

Hepatic FXR’s
Protective Role Against NASH Development in a High-Fat Diet Induced NAFLD
Mouse Model

Laura Armstrong,
Post-Doctoral Research Fellow, Rutgers University

2:35 p.m.

Vendor Exhibit & Coffee

3:00 p.m.

Novel Metabolite
ID Platform for Therapeutic Proteins

Xiang Yu,
PhD, Associate
Principle Scientist, PPDM Preclinical ADME Metabolite

Merck, West
Point, NJ







NJ-DMDG Steering Committee 2018-2019
Name Company E-mail address Responsibility
Beth Joshi Merck elizabeth.joshi@merck.com Chair, 2018-19
Imad Hanna Novartis imad.hanna@novartis.com Chair Elect, 2019-20
Matthew Hoffmann Celgene mjhoffman@celgene.com Treasurer
Naiyu Zheng BMS naiyu.zheng@bms.com Vendor Liaison
Manthena Varma Pfizer Manthena.V.Varma@pfizer.com Past Chair, 2017-18
Bo Wen GSK bo.1.wen@gsk.com Past Chair, 2016-17
Lauren Aleksunes Rutgers University aleksunes@eohsi.rutgers.edu Past Chair, 2015-16
Wing Lam Janssen R&D wlam@its.JnJ.com Past Chair, 2013-14
Allen Jones allen.n.jones@verizon.net Past Chair, 2012-13
Anima Ghosal Kean University ghosala@aol.com Member
Ron Kong PTC Therapeutics rkong@ptcbio.com Member
Lei Tang Sanofi Lei.Tang@sanofi.com Member
Li Yu Roche li.yu.ly1@roche.com Member
Fan Wu Celgene fwu@celgene.com Member
Jin Wu Merck Jin_wu@merck.com Member
Zhao pie Zeng zhaopiezeng@gmail.com Member
Carolina Berthiaume carolina.berthiaume@gmail.com Member
Maria Markowska Mmaryla5@yahoo.com Member



Directions to the Palace at Somerset Park

    333 Davidson Avenue, Somerset, NJ 08873

    Phone: 732-302-9922
    [ website ]

From the New Jersey Turnpike:

    Exit 10 to Interstate 287 North.
    Follow 10 miles to Exit 10 (527 New Brunswick — South Bound Brook).
    Take Easton Ave towards South Bound Brook to first light,
    make left (Davidson Ave.)

From New York City:

    Lincoln Tunnel to N.J. Turnpike South.
    Follow N.J. Turnpike directions mentioned above.

From Route 287:

    If traveling north:

      Exit 10 (527 New Brunswick — South Bound Brook).
      Follow sign towards Bound Brook, to light
      make left (Davidson Ave.)
    If traveling south:

      Exit 10 (527 New Brunswick).
      Left on Easton Ave., to light,
      make left (Davidson Ave).

From Newark Airport:

    Take NJ Turnpike South to Exit 10
    I-287 North to Exit 10 (Easton Ave)
    at first light, go left on Davidson Ave.
    Hotel immediately on left.