“Current Topics in DMPK and the New DDI Draft Guidance”

Crowne Plaza Somerset-Bridgewater Hotel
110 Davidson Avenue
Somerset, New Jersey

April 26, 2012
8:00 am – 3:45 pm


08:00 am
Registration / Continental Breakfast / Vendor Exhibit

09:00 am
Introductory Remarks
Dr. Lian Zhou, Chair, NJDMDG

09:10 am
Drug Metabolism in Chimeric Mice with Humanized Liver [slides (PDF)] Professor Hiroshi Yamazaki, Showa Pharmaceutical University, Machida, Tokyo

10:00 am
ADME in NAFLD: Genes and Big Jeans Increase the Risk of Adverse Drug Reactions [slides (PDF)] Professor Nathan Cherrington, Pharmacology & Toxicology, University of Arizona, Tucson, AZ.

10:45 am
Vendor Exhibit & Coffee Break

11:30 am
Clarity on Transporters: Navigating the New FDA Draft Guidance on Drug Interactions [slides (PDF)] Dr. Sid Bhoopathy, Chief Operating Officer, Absorption Systems, Exton, PA.

12:15 pm
Lunch & Vendor Exhibit

01:45 pm
The 2012 FDA Draft Guidance on Drug-drug Interactions: Enzyme Induction and Beyond [slides (PDF)] Dr. Michael Sinz, Research Fellow, Metabolism and Pharmacokinetics, Bristol-Myers Squibb

02:30 pm
Vendor Exhibit & Coffee Break

03:00 pm
Update on the Progress of the IQc/FDA/Academia Collaboration on DDI Prediction and Thoughts on the DDI Draft Guidance
Dr. Scott Obach, Senior Research Fellow, Pharmacokinetics, Dynamics, and Drug Metabolism Department, Pfizer

03:45 pm
Program Closure