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Officers
Chair
Daniel Seidel
Assistant Professor
Department of Chemistry
and Chemical Biology
Rutgers University
610 Taylor Road
Piscataway, NJ 08854
http://seidel-group.com/
(732)445-6921
Past Chair (2008)
Joe Kozlowski
Schering Plough
2015 Galloping Hill Rd.
Kenilworth NJ 07033
(908)740-3488
Treasurer
Eric Mertz
Hoffmann-La Roche Inc.
Discovery Chemistry
340 Kingsland St.
Nutley, NJ 07110
(973)235-4430
(973)235-6389 (fax)
Members
Lawrence J. Williams
Associate Professor
Chemistry & Chemical Biology
Rutgers, The State Univ. of NJ
610 Taylor Rd
Piscataway, N.J. 08854
rutchem.rutgers.edu/~ljwweb/
(732)445-7916
(732)445-6921
Albert DelMonte
Bristol-Myers Squibb
Process Research & Development
P.O. Box 191
New Brunswick, NJ 08903
(732)227-6915
Amjad Ali
Merck Research Laboratories
RY121-267
126 E. Lincoln Ave.
Rahway, NJ 07065
(732)594-8549
Akin Davulcu
Bristol-Myers Squibb
One Squibb Drive
New Brunswick, NJ 08903
(732)227-7479
Dong Xiao
Schering Plough
2015 Galloping Hill Rd.
Kenilworth NJ 07033
(908)740-4484
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NJ-ACS Organic Topical Group – Past Meetings
Meetings:
[ current
| past
]
Past Meetings
[ Jan 2011
| Nov 2010
| Aug 2009
| Nov 2008
| May 2008
| Oct 2007
| May 2007
| Nov 2006
]
Rutgers University and
The North Jersey American Chemical Society
Organic Topical Group
Present:
Organic and Bioorganic Chemistry:
Pure, Applied, Historical
A symposium in honor of
Professor Spencer Knapp
on the Occasion of his 60th Birthday
Friday, January 14, 2011
at the
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Wright-Rieman Auditorium,
Wright Chemistry Building
Dept. of Chemistry and Chemical Biology,
610 Taylor Rd,
Rutgers University (Busch Campus),
Piscataway, NJ 08854
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This symposium is made possible by generous financial support from
Affymax, Inc.
Amgen
BMK Scientific Consulting
Bristol-Myers Squibb Co.
Lexicon Pharmaceuticals
New Jersey Center for Biomaterials
Novartis
Organic Syntheses
Protagonist Pharmaceuticals
Rutgers, The State University of New Jersey
and Private Donations
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Program
9:30 – 10:00 Registration
10:00 – 10:10 Welcoming Remarks
10:10 – 11:00 Professor James Coward (University of Michigan)
Carbohydrate Chemistry: How Sweet It Is!
11:00 – 11:50 Professor Chulbom Lee (Seoul National University)
Synthesis of Complex Natural Products via Organometallic Catalytic Approaches
11:50 – 1:00 Lunch Break
1:00 – 1:50 Professor Erik Sorensen (Princeton University)
Practical Asymmetric Hydrogenation and Hydroformylation
1:50 – 2:40 Professor Daniel Seidel (Rutgers University)
New Approaches to the Synthesis of Nitrogen Heterocycles
2:40 – 3:30 Professor Lawrence Williams (Rutgers University)
The Total Synthesis of Bioactives via Integrated Routing
3:30 – 3:50 Coffee Break
3:50 – 4:40 Professor Heinz Roth (Rutgers University)
Benzene - Faraday, Kekulé and Beyond
4:40 – 5:30 Professor J. R. Camille Falck (UT Southwestern)
Development of New Synthetic Methodology and Its
Application in Natural Products Synthesis
5:45 – 7:00 Reception
Profs. Harvey Schugar and Joseph Potenza (Rutgers University)
| Program |
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9:30
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Registration
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10:00
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Welcoming Remarks
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Professor James Coward
(University of Michigan)
Carbohydrate Chemistry: How Sweet It Is!
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Professor Chulbom Lee
(Seoul National University)
Synthesis of Complex Natural Products via Organometallic Catalytic Approaches
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Professor Erik Sorensen
(Princeton University)
Design and synthesis of molecular scaffolds with anti-infective activity
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Professor Daniel Seidel
(Rutgers University)
New Approaches to the Synthesis of Nitrogen Heterocycles
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Professor Lawrence Williams
(Rutgers University)
The Total Synthesis of Bioactives via Integrated Routing
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Professor Heinz Roth
(Rutgers University)
Benzene - Faraday, Kekulé and Beyond
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Professor J. R. Camille Falck
(UT Southwestern)
Development of New Synthetic Methodology and Its
Application in Natural Products Synthesis
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5:45
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Reception
Profs. Harvey Schugar and Joseph Potenza
(Rutgers University)
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Please join us for this free symposium and the reception to follow
[ donation
| flyer
| maps & directions
| parking instructions
]
|
Free Parking on Day of Event:
Guests may park in Lots 51, 54, 59, & 67 without permit on Jan. 14, 2011:
- Lot 51: Bartholomew Rd., adjacent Rutgers Federal Credit Union
- Lot 54: Off of Taylor Road, off Davidson
- Lot 59: Behind Engineering and Busch Student Center; access from Bowser Road
- Lot 67: Bartholomew Rd., near intersection w/Bevier Road.; behind Biomed. and Civil Eng.
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Note: The Symposium is free but
pre-registration
is required.
Please register by January 7.
You are also invited to make a $50 donation.
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Organizing Committee:
Daniel Seidel
(Chair, Rutgers)
Joe Kozlowski
(Merck)
Dong Xiao
(Merck)
Lawrence Williams
(Rutgers)
Amjad Ali
(Merck)
Kshitij Thakkar
(Roche)
Eric Mertz
(Roche)
Akin Davulcu
(BMS)
Speakers
Prof Spencer Knapp
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Prof James Coward
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Prof Chulbom Lee
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Prof Erik Sorensen
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Prof Daniel Seidel
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Prof Lawrence Williams
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Prof Heinz Roth
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Prof Camille Falck
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North Jersey ACS Organic Topical Group Announces:
The Award for Creativity in
Molecular Design
and Synthesis
2010 Award Recipient:
Prof. David A. Evans (Harvard University)
Wednesday, November 17, 2010
at The Palace at Somerset Park
333 Davidson Ave, Somerset, NJ 08873
[ directions
| flyer
| Registration (below)
]
| 12:00 noon |
Sign-in begins |
| 1:00 PM |
Symposium |
| 6:30 PM |
Dinner |
Invited Speakers
Prof Gregory Fu
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Prof Daniel Seidel
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Prof Jonathan Ellman
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Prof Jim Leighton
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Prof Scott Miller
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Prof David A. Evans
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-->
“Palladium- and Nickel-Catalyzed Cross-Couplings of
Alkyl Electrophiles”
Prof. Gregory Fu, Massachusetts Institute of Technology
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“Redox Neutral Reaction Cascades”
Prof. Daniel Seidel, Rutgers University
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“Application of New C-C Bond Forming Reactions to
Natural Product Synthesis”
Prof. Jonathan Ellman, Yale University
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“Doing More with Less: Design of Tandem Reactions for
Efficient Chemical Synthesis”
Prof. Jim Leighton, Columbia University
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“Asymmetric Catalysis with Amino Acids and Peptides:
Structure-Function Studies”
Prof. Scott Miller, Yale University
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Keynote Address
“Recent Studies in the Synthesis of Complex Alkaloids”
Prof. David A. Evans, Harvard University
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Organizing Committee:
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Daniel Seidel (Chair, Rutgers)
Joe Kozlowski (Merck)
Dong Xiao (Merck)
Lawrence Williams (Rutgers)
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Amjad Ali (Merck)
Kshitij Thakkar (Roche)
Eric Mertz (Roche)
Akin Davulcu (BMS)
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August 13, 2009 – Symposium and Celebration
‘A Celebration of Organic Synthesis’
to mark the 65th Birthday of
Prof. Amos B. Smith III
Keynote Speaker:
Professor Amos B. Smith III
Thursday August 13, 2009
Rutgers, Busch Campus
Science and Engineering Resource Center
118 Frelinghuysen Rd, Piscataway, NJ 08854
[ Directions & Parking |
Registration (below)
| Flyer
]
Registration fee: $100.00 (Symposium, & Lunch)
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Registration
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8:30 AM
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Symposium
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9:00 AM
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Lunch
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12:00 noon
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Please register according to the instruction below
Invited Speakers
I.
“Bridged Polycyclic Natural Products: Inspirational Targets for Total Synthesis”
Professor John L Wood (Colorado State University)
II.
“Total Synthesis of Azinothricin and Kettapeptin and Allied Chemical Genomics Studies on the A83586C Class of Antitumor Antibiotics”
Professor Karl Hale (Queen's University, Belfast)
III.
“Complex Molecule Synthesis” (tentative)
Professor Jon D. Rainier (University of Utah)
IV.
“New catalytic Strategies for Chemical Synthesis”
Professor Matthew Gaunt (University of Cambridge)
V.
“Studies Directed Toward the Synthesis of Natural Products”
Professor Gary A. Sulikowski (Vanderbilt University)
VI.
“Evolution of Anion Relay Chemistry (ARC): Construction of Architecturally Complex Natural and Unnatural Products”
Professor Amos B. Smith III (University of Pennsylvania)
– Keynote Address
I.
title
presenter
position
affil
II.
Site-Specific Measurements of Motion
in Micro-Crystalline Proteins
and Biomolecules by Solid-State NMR
speaker
position
affil
city
Thursday November 13, 2008
The Award for Creativity in Molecular Design and Synthesis
2008 Award Recipient:
Dr. Malcolm MacCoss
Thursday November 13, 2008
Palace at Somerset Park, 333 Davidson Ave, Somerset, NJ 08873
[ Directions
| Flyer
]
Registration fee: $125.00 (Symposium, Reception & Dinner)
Students & Post-Docs: $100.00
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Registration
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12:00 noon
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Symposium
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1:00 p.m.
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Reception
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5:45 p.m.
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Dinner
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6:30 p.m.
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Awards Address
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7:30 p.m.
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Invited Speakers
I.
“Three Decades of Research on Stereochemical Control”
Professor David Evans (Harvard University)
II.
“New Catalysis Concepts”
Professor David MacMillan (Princeton University)
III.
“Discovery of Second Generation NK-1 Antagonists”
Dr. Sandy Mills (Merck & Co, Inc.)
IV.
“Catalysis via Cationic Intermediate”
Professor Dean Toste (University of California, Berkeley)
V.
“A Challenge for Total Synthesis: Atom Economy”
Professor Barry Trost (Stanford University)
VI.
“A Career In Chemistry And Medicinal Chemistry: Some Personal Reflections On One Path Taken”
Dr. Malcolm MacCoss (Schering-Plough Research Inst.)
I.
title
presenter
position
affil
II.
Site-Specific Measurements of Motion
in Micro-Crystalline Proteins
and Biomolecules by Solid-State NMR
speaker
position
affil
city
May 2008 Meeting and Symposium
Pharmaceutical Success Stories
Thursday May 22, 2008
Palace at Somerset Park, 333 Davidson Ave, Somerset, NJ 08873
[ Directions
]
Registration fee: $95.00 (Symposium and Lunch)
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Registration
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8:30 a.m.
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Symposium
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9:00 a.m. – 4:30 p.m.
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Lunch
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12:30 p.m.
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Invited Speakers
I.
“Process Chemistry at GlaxoSmithKline, The Development of a Manufacturing Route to a Cathepsin K Inhibitor”
William Clark & Robert W. Marquis (GlaxoSmithKline)
II.
“Discovery and Development of SGLT-2 Inhibitors”
Prashant Desphande & Wei Meng (Bristol Myers Squibb)
III.
“Natural Products in Drug Discovery: The Development of Cancidas®”
James Balkovec (Merck Research Laboratories)
IV.
“From R1479 to R1626: Discovery and Advancement of 4’-Substituted Nucleosides for the Treatment of Hepatitis C”
David Smith (Roche)
V.
“The Discovery of Varenicline, a Nicotinic Receptor Partial Agonist for Smoking Cessation”
Jotham Coe (Pfizer)
I.
title
presenter
position
affil
II.
Site-Specific Measurements of Motion
in Micro-Crystalline Proteins
and Biomolecules by Solid-State NMR
speaker
position
affil
city
Drugs from Academia: Marketed Drugs from Academic Labs
Friday, October 26, 2007
Palace at Somerset Park, 333 Davidson Ave, Somerset, NJ 08873
[ Directions
]
Registration fee: $95.00 (Symposium and Lunch)
|
Registration
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8:30 a.m.
|
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Symposium
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9:00 a.m. – 4:30 p.m.
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Lunch
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12:30 p.m.
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Invited Speakers
I.
“Discovery of Alimta, a Broadly Effective New Antitumor Agent”
Edward C. Taylor (Princeton University)
II.
“SAHA (Vorinostat): The First Anticancer HDAC Inhibitor Approved for Human Use”
Ronald Breslow (Columbia University)
III.
“Didanosine (ddI): A Member of the Versatile 2',3'-Dideoxy Family of Biomedicinal Nucleoside Analogues”
Morris J. Robins (Brigham Young University)
IV.
“Basic Science to the Market. The Discovery of LyricaŽ”
Richard B. Silverman (Northwestern University)
V.
“The Discovery of 3TC and FTC”
Dennis C. Liotta (Emory Uinversity)
I.
title
presenter
position
affil
II.
Site-Specific Measurements of Motion
in Micro-Crystalline Proteins
and Biomolecules by Solid-State NMR
speaker
position
affil
city
May 24 2007 Meeting and Symposium
[ Group Photo ]
New Methods and Strategies for Heterocyclic Synthesis
|
Thursday, May 24, 2007
Registration fee: $95.00 (Symposium and Lunch)
|
Registration
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8:30 a.m.
|
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Symposium
|
9:15 a.m.
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Lunch
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12:00 noon
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-->
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Invited Speakers
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Due to unforeseen circumstances Professor Harran had to cancel his presentation. Professor Chulbom Lee from Princeton University has agreed to step in as a replacement speaker. The North Jersey ACS, Organic Topical Group organizing committee is grateful for his participation at such short notice.
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I.
"Strategies for the Synthesis of Heterocyclic Natural Products"
Stephen F. Martin (University of Texas, Austin)
II.
"Chemoenzymatic Synthesis of Alkaloids: A Multi-Generational Approach"
Tomas Hudlicky (Brock University, St. Catharines, Ontario, Canada)
III.
"A Conducted Tour of Recent Heteroaromatic Directed ortho Metalation"
Victor Snieckus (Queen's University, Kingston, Ontario, Canada)
IV.
"Synthesis of Heterocycles via Transition Metal-Mediated Catalysis"
Chulbom Lee (Princeton University)
V.
"Cascade Reaction in Complex Alkaloid Synthesis"
Mohammad Movassaghi (MIT)
I.
title
presenter
position
affil
II.
Site-Specific Measurements of Motion
in Micro-Crystalline Proteins
and Biomolecules by Solid-State NMR
speaker
position
affil
city
Speakers and Section Officers at the May 2007 Symposium
From left to right:
Dr. Binh Vu,
Prof. Victor Snieckus,
Prof. Lawrence Williams
Prof. Steve Martin,
Prof. Chulbom Lee,
Dr. Albert DelMonte,
Prof. Mo Movassaghi,
Dr. Amjad Ali,
Dr. Gabor Butora,
Dr. Dong Xiao,
Prof. Tomas Hudlicky.
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Friday, November 17, 2006
Discovery, Selection, and Development of Drug Candidates:
A Senior Leadership Perspective
[ photos ]
Poster - Click to enlarge
Speakers:
Keynote Address:
Dr. P. Roy Vagelos (Retired Chairman and CEO, Merck & Co., Inc.)
“The Changing Pharmaceutical Industry”
Dr. Carl Decicco (Bristol-Myers Squibb)
“Innovation in Drug Discovery”
Dr. Paul Feldman (GlaxoSmithKline)
“PPAR Pan Agonists-The Next Generation
PPAR Ligands”
Dr. Malcolm MacCoss (Merck)
“EMEND(c) (Aprepitant) a potent, orally active
Substance P Antagonist for the treatment of Chemotherapy Induced Nausea
and Vomiting (CINV), from the medicinal chemistry bench to the
clinic”
Dr. Bruce Roth (Pfizer)
“The Discovery and Development of
Lipitor”
Registration Form (pdf)
Location
Somerset Marriott
110 Davidson Avenue
Somerset, New Jersey 08873
(Directions)
This event involved 4 Vice Presidents in charge of research at 4 of the largest Pharma compan
ies in the US. The evening ended with a keynote talk by Dr. P. Roy Vagelos (retired Chariman
and CEO, Merck).
(Click pictures to enlarge)
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Dr. P. Roy Vagelos provides Keynote Address
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Drs. Paul Feldman, Malcolm MacCoss, Bruce Roth, Carl Decicco, and 2006 OTG Committee
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