Organic Topical Group

The North Jersey ACS Organic Topical Group Congratulates Professor K.C. Nicolaou on his receipt of the 2012 Award for Creativity in Molecular Design and Synthesis!

The members of the North Jersey ACS OTG thank all of the speakers, attendees and corporate sponsors for helping to make this year’s award symposium a success! Left to right: Professor Lawrence Williams (Rutgers), Professor Daniel Seidel (Rutgers), Professor K.C. Nicolaou (Scripps), Dr. Akin Davulcu (BMS), Dr. Amjad Ali (Merck), Dr. Michael Miller (BMS), Dr. Naresh Jain (TCRS-US), Dr. Steven Silverman (BMS)

Invited Speakers

• “Bridged Polycyclic Natural Products: Inspirational Targets for Total Synthesis”
  Professor John L Wood (Colorado State University)
• “Total Synthesis of Azinothricin and Kettapeptin and Allied Chemical Genomics Studies on the A83586C Class of Antitumor Antibiotics”
  Professor Karl Hale (Queen’s University, Belfast)
• “Complex Molecule Synthesis” (tentative)
  Professor Jon D. Rainier (University of Utah)
• “New catalytic Strategies for Chemical Synthesis”
  Professor Matthew Gaunt (University of Cambridge)
• “Studies Directed Toward the Synthesis of Natural Products”
  Professor Gary A. Sulikowski (Vanderbilt University)
• “Evolution of Anion Relay Chemistry (ARC): Construction of Architecturally Complex Natural and Unnatural Products”
  Professor Amos B. Smith III (University of Pennsylvania) – Keynote Address

Invited Speakers

• “Three Decades of Research on Stereochemical Control”
  Professor David Evans (Harvard University)
• “New Catalysis Concepts”
  Professor David MacMillan (Princeton University)
• “Discovery of Second Generation NK-1 Antagonists”
  Dr. Sandy Mills (Merck & Co, Inc.)
• “Catalysis via Cationic Intermediate”
  Professor Dean Toste (University of California, Berkeley)
• “A Challenge for Total Synthesis: Atom Economy”
  Professor Barry Trost (Stanford University)
• “A Career In Chemistry And Medicinal Chemistry: Some Personal Reflections On One Path Taken” Dr. Malcolm MacCoss (Schering-Plough Research Inst.)

Thursday May 22, 2008
Palace at Somerset Park, 333 Davidson Ave, Somerset, NJ 08873

Invited Speakers

• “Process Chemistry at GlaxoSmithKline, The Development of a Manufacturing Route to a Cathepsin K Inhibitor”
  William Clark & Robert W. Marquis (GlaxoSmithKline)
• “Discovery and Development of SGLT-2 Inhibitors”
  Prashant Desphande & Wei Meng (Bristol Myers Squibb)
• “Natural Products in Drug Discovery: The Development of Cancidas®”
  James Balkovec (Merck Research Laboratories)
• “From R1479 to R1626: Discovery and Advancement of 4’-Substituted Nucleosides for the Treatment of Hepatitis C”
  David Smith (Roche)
• “The Discovery of Varenicline, a Nicotinic Receptor Partial Agonist for Smoking Cessation”
  Jotham Coe (Pfizer)

Friday, October 26, 2007

Palace at Somerset Park, 333 Davidson Ave, Somerset, NJ 08873

Invited Speakers

• “Discovery of Alimta, a Broadly Effective New Antitumor Agent”
  Edward C. Taylor (Princeton University)
• “SAHA (Vorinostat): The First Anticancer HDAC Inhibitor Approved for Human Use”
  Ronald Breslow (Columbia University)
• “Didanosine (ddI): A Member of the Versatile 2′,3′-Dideoxy Family of Biomedicinal Nucleoside Analogues”
  Morris J. Robins (Brigham Young University)
• “Basic Science to the Market. The Discovery of Lyrica®”
  Richard B. Silverman (Northwestern University)
• “The Discovery of 3TC and FTC”
  Dennis C. Liotta (Emory Uinversity)

Thursday, May 24, 2007

From left to right: Dr. Binh Vu, Prof. Victor Snieckus, Prof. Lawrence Williams Prof. Steve Martin, Prof. Chulbom Lee, Dr. Albert DelMonte, Prof. Mo Movassaghi, Dr. Amjad Ali, Dr. Gabor Butora, Dr. Dong Xiao, Prof. Tomas Hudlicky.

Invited Speakers

• “Strategies for the Synthesis of Heterocyclic Natural Products”
  Stephen F. Martin (University of Texas, Austin)
• “Chemoenzymatic Synthesis of Alkaloids: A Multi-Generational Approach”
  Tomas Hudlicky (Brock University, St. Catharines, Ontario, Canada)
• “A Conducted Tour of Recent Heteroaromatic Directed ortho Metalation”
  Victor Snieckus (Queen’s University, Kingston, Ontario, Canada)
• “Synthesis of Heterocycles via Transition Metal-Mediated Catalysis”
  Chulbom Lee (Princeton University)
• “Cascade Reaction in Complex Alkaloid Synthesis”
  Mohammad Movassaghi (MIT)

Friday, November 17, 2006

Location
Somerset Marriott
110 Davidson Avenue
Somerset, New Jersey 08873

Drs. Paul Feldman, Malcolm MacCoss, Bruce Roth, Carl Decicco, and 2006 OTG Committee

Invited Speakers

• Dr. P. Roy Vagelos (Retired Chairman and CEO, Merck & Co., Inc.)
  “The Changing Pharmaceutical Industry”
• Dr. Carl Decicco (Bristol-Myers Squibb)
  “Innovation in Drug Discovery”
• Dr. Paul Feldman (GlaxoSmithKline)
  “PPAR Pan Agonists-The Next Generation PPAR Ligands”
• Dr. Malcolm MacCoss (Merck)
  “EMEND(c) (Aprepitant) a potent, orally active Substance P Antagonist for the treatment of Chemotherapy Induced Nausea and Vomiting (CINV), from the medicinal chemistry bench to the clinic”
• Dr. Bruce Roth (Pfizer)
  “The Discovery and Development of Lipitor”