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Meeting Registration
Meeting Calendar
2011 Fall Vendor Show
2010 Fall Vendor Show
2009 Fall Vendor Show
2008 Fall Vendor Show
History of the MSDG
Spectrometry Links
Job Openings
Photos
Awards
Sponsors
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Upcoming October Meetings:
MSDG will hold two sevents in Langhorne PA on
Monday Oct 3
and
Wednesday Oct 5
in conjunction with CPSA
The meetings are free but registration is required for each – see below
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1st Event:
CPSA USA Symposium
Monday, October 3, 12:00-4:00 PM
Bucks County Sheraton Hotel,
Langhorne, PA
[ CPSA Website ] for full meeting information, travel, etc
Topic:
Pharmaceutical Sciences Workshop:
Impurities & Degradants
Co-sponsored by the
North Jersey Mass Spectrometry Discussion Group
[ register for first event ]
Speakers:
Guodong Chen, Ph.D. Bristol-Myers Squibb
Company, Princeton, NJ
"Characterization of Impurities and Degradants
in Biologics Discovery and Development"
Min Li, Ph.D. Merck & Co.,
Summit, NJ
"Application of LC-MSn
molecular fingerprinting in conjunction with mechanism-based stress studies in
the elucidation of drug degradation products and degradation pathways"
David Liu, Ph.D. GlaxoSmithKline, King
of Prussia, PA
“Analytical Challenges in Controlling Genotoxic
Impurities”
Gary Martin, Ph.D. Merck & Co.
Summit, NJ
"To Isolate or Not: The Sometimes Circuitous Characterization
of a Degradant"
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2nd Event:
CPSA/MSDG Joint Meeting
Wednesday, October 5, 6:30-9:00 PM
Bucks County Sheraton Hotel,
Langhorne, PA
[ CPSA Website ] for full meeting information, travel, etc
Keynote Dinner Lectures sponsored by
Bristol-Myers
Squibb ●
GlaxoSmithKline
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McKinley Scientific
●
New Objective
[ register for second event ]
Topics and Speakers:
Liquid Chromatography-Mass Spectrometry
in Pharmacology Research and its Translation into Clinical Applications
Ian Blair,
University of Pennsylvania
Presentation of the Distinguished
Analytical Scientist Award
presented by
Tom Covey, AB Sciex, and Rick King, PharmaCadence
A Scientific
Adventure. LC/MS: From Academia to Entrepreneurship
Jack Henion, Advion BioSciences &
Cornell University
Free Dinner!
Arrive early to receive
your complimentary CPSA 2011 hat!
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Upcoming Meeting:
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The NJ Mass Spectrometry Discussion Group presents
The
March Meeting
– Bruker Daltonics night
I.
“Combining Flexibility and Ultrahigh Performance in Mass Spectrometry”
Dr. Chris Thompson,
FTMS Applications Scientist at Bruker Daltonics
II.
“Characterization of HmqF, a Protein Involved in the Biosynthesis of Unsaturated Quinolones Produced by Burkholderia thalandensis”
Dr. Darren Hansen,
Assistant Professor,
Rutgers University Chemistry Dept, Newark, NJ
• Sponsored by •
Bruker Daltonics
at the
Holiday Inn, Somerset, NJ
on
Tuesday, March 20, 2012
| 5:30 pm: |
Social and registration |
| 6:15 pm: |
Complimentary Dinner |
| 7:00 pm: |
Welcome and Opening Remarks |
| 7:05 pm: |
Dr. Chris Thompson, FTMS Applications Scientist at Bruker Daltonics |
| 8:00 pm: |
Dr. Darren Hansen, Rutgers University |
| 8:55 pm: |
Closing Remarks |
Speaker:
Kathy Kellersberger, Ph.D.
Senior Product Specialist at Bruker Daltonics
Presentation:
“From Discovery to the Routine – Mass Spectrometric Workflows for the Characterization of Protein-Based Biopharmaceuticals”
Abstract:
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Characterization of a biopharmaceutical compound is essential at
each stage during its life-cycle. However, characterization of
protein-based biopharmaceuticals is challenging in comparison with
their small molecule counterparts due to their high molecular weight
and heterogeneous nature. Of the analytical tools available, mass
spectrometric methods are some of the most powerful. Here we present
an overview of Bruker Daltonics solutions including an automated
rapid workflow for the routine characterization of biopharmaceutical
products; discovery and development tools for more detailed
characterization including primary structure and N-terminal sequence
determination, determination of post-translational modifications
including glycosylation patterns, and determination of disulphide
bonds.
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Speakers & Titles:
TBA
I.
“From Discovery to the Routine – Mass Spectrometric Workflows for the Characterization of Protein-Based Biopharmaceuticals”
Kathy Kellersberger, Ph.D.
Senior Product Specialist at Bruker Daltonics
Abstract:
Characterization of a biopharmaceutical compound is essential at
each stage during its life-cycle. However, characterization of
protein-based biopharmaceuticals is challenging in comparison with
their small molecule counterparts due to their high molecular weight
and heterogeneous nature. Of the analytical tools available, mass
spectrometric methods are some of the most powerful. Here we present
an overview of Bruker Daltonics solutions including an automated
rapid workflow for the routine characterization of biopharmaceutical
products; discovery and development tools for more detailed
characterization including primary structure and N-terminal sequence
determination, determination of post-translational modifications
including glycosylation patterns, and determination of disulphide
bonds.
II.
“Plasma Peptide Biomarkers: From Sample to Spectrum”
Jizu Yi, Ph.D.
Principal Scientist / Proteomics R & D at BD Diagnostics
Abstract:
Plasma peptides are found to be rich in a human plasma sample, and
contain status information of a variety of diseases. The discovered
peptide markers such as FPA, GLP-1, GIP, Glucagon, and Ghrelin, are
potentially developed for clinical application. However, these
potential metabolic peptide biomarkers like other peptides are
subject to preanalytical variability, specifically due to the
instability caused by intrinsic proteolysis. The proteolytic
instability may result in a barrier in translating discovered
biomarkers from research into applications. Using time-course MS
analysis, we have characterized the kinetics of digestion of a
peptide as a Sequential Multiple-Step Reaction (SMSR). We also
developed a time-course MALDI-TOF MS method to evaluate the stability
of a potential peptide marker from sample to spectrum. We further
developed a technology to minimize this variability and instability
using enzymatic inhibitors in the blood collection tube. Stabilization
of plasma peptides enables them for further biomarker development
from discovery to application.
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Attendance is free of charge, compliments of our sponsor!
“Recent applications and technology for intact pharmaceutical analysis using High Mass MALDI TOF”
Ryan J. Wenzel, PhD, CovalX
“TOFs and Traps: From the Histone Code to Mars”
Robert J. Cotter, Johns Hopkins University School of Medicine
Presentation II:
“Formation of reactive metabolites by cytochrome P450-dependent oxidation versus glucuronidation”
Joanna Barbara, Ph.D
XenoTech LLC. - Mass Spectrometry Specialist
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If you will be attending dinner,
please register online at this link:
REGISTER HERE.
Help us keep track of our attendees by registering early and remember to cancel
your registration if you cannot attend.
Note:
The CPSA Vendor Session, Exhibition & Keynote Dinner Lectures are
free to NJ MSDG members.
Note: The CPSA meeting runs from Oct 27 through Oct 30.
For program and registration information for the rest
of the meeting,
click
here.
Photo from the November 2011 Meeting
Front: Steven Gross, Jim Lau;
Back: Mingxiang Lin, Wayne Heacock, Bryan Lavery, Ron Kong
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Photo from the MSDG 2011 Annual Fall Vendor Show
and Distinguished Lecture –
September, 2011
Left: Mingxiang Lin, Right: Distinguished Lecturer Professor David C. Muddiman
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Photo from the June 2011 Meeting
Front: Gene Ciccimaro, Jerry Pappas, Qian Ruan
Back: Safet Palamar, Mingxiang Lin
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Photos from the May 2011 Meeting
1. 2011 NJACS-MSDG Student Travel Award Winner, Rosalynn Molden, Princeton University
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2. Front: Hui Wei, Lewis M. Brown, John Venesky, and Safet Palamar
Back: Mingxiang Lin, Vin Dell'Ova, Aviva deBeer-heidt, and Robert M Iannucci
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Photo from the April 2011 Meeting
Front: Chris Colangelo, Tom Covey and Graham Gibson. Back: Fangbiao Li, Mingxiang Lin and Robert M Iannucci
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Photos from the March 2011 Meeting
1. NJACS-MSDG 2011 award lecture recipients with the Board.
Front: Benjamin A. Garcia, Mickey O'Brian, Kuangnan Qian.
Back: Safet Palamar, Ron Kong, Mingxiang Lin and Robert M Iannucci
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2. Early Career Award presented to Benjamin A. Garcia, Ph.D.
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3. Achievements in Mass Spectrometry Award presented to Kuangnan Qian, Ph.D.
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4. Distinguished Service Award presented to Heather Coales
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Photo from the February 2011 Meeting
Speakers with the Board.
Front:
Kathy Kellersberger, Doug Boyd, Jizu Yi
Back:
Safet Palamar, Mingxiang Lin, Ron Kong, and Robert M Iannucci
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Photos from the December 2010 Meeting
1. MSDG appreciates John's contributions to the community: John Castoro (2010 Chair) and Mingxiang Lin
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2. Speakers with the Board. Front: Ragu Ramanathan and Veronica Zelesky. Back: Graham Gibson, Mingxiang Lin and John Castoro
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Photos from the NJACS MS Vendor Show - Sept 2010
1. Mixer
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2. Prof. R. Graham Cooks receives the 2010 NJ-ACS MSDG Distinguished Lectureship Award
Dr. John Castoro, NJACS MSDG Chair (left) and Prof. R. Graham Cooks (right)
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Photos from the May 2010 Meeting
1. NJACS-MSDG 2010 student travel award recipients with the Board.
Front: Barry Zee, Diana Johnson and Changching Chan.
Back: Mingxiang Lin and John Castoro
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2. Speakers with the Board.
Front: Jose Castro Perez and Brandon Ruotolo.
Back: Mingxiang Lin, John Castoro and John Venesky.
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Photo from the April 2010 Meeting
Speakers with the Board. Front: Paul West, Jim Lau; Back: Mingxiang Lin, John Castoro, Ron Kong, and Kathleen Anderson
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Photo from the March 2010 Meeting
Speakers with the Board.
Front:
Guodong Chen, Wendy Zhong, Doug Boyd
Back:
Victor Fursey, Mingxiang Lin, John Castoro
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Photo from the Feb 2010 Meeting
Speakers with the Board.
Front: Yves LeBlanc, Joseph Dixon
Back: Mingxiang Lin, John Castoro, Graham Gibson, Ron Kong
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Photos from the Dec 2009 Meeting
1. NJACS-MSDG 2009 award recipients with the Board.
Front: Jerry Pappas, Tim Olah, Qian Ruan
Back: Mingxiang Lin, John Castoro, Kathleen Cox, Mickey O'Brien
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2. Speakers with the Board.
Front: Stephen Dueker, Griff Humphries
Back: Mickey O'Brien, Mingxiang Lin, Kathleen Cox, John Castoro
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Photo from the Nov 2009 Meeting
Front: Professor Robert Cotter, Dr. Ryan Wenzel. Rear: John Castoro, Tom Moran, Kathleen Cox, Scott Kuzdal, Mingxiang Lin
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Photos from the May 2009 Meeting
1. ASMS Student award winners with the NJ MSDG Board.
Front: Junfeng Xiao, Maria Cecilia Della Valle, Mariana Plazas-Mayorca
Back: Mingxiang Lin, John Castoro, Brandy Young, Kathleen Cox, Mickey O'Brien
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2. Speakers with the Board.
Front: John Venesky, Joanna Barbara, Ignatius Kass
Back: Mingxiang Lin, John Castoro, Kathleen Cox, Brandy Young, Mickey O'Brien
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Photo from the April 2009 Meeting
Sitting: Russell Grant, Pat Bennett, Liaxin Wang
Standing: John Castoro, Kathleen Cox, Brandy Young, Mingxiang Lin
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Photo from the March 2009 Meeting
Bottom row:
Dr, William Erb, Ethicon; Prof. Jonathan Sweedler, University of Illinois;
Top Row: Mingxiang Lin, Secretary; Kathleen Cox, Chair; Doug Boyd, Bruker Daltonics; John Castoro, Treasurer
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The MSDG Annual Fall Vendor Show and Distinguished Lecture
was held on Monday, Sept 21, 2009
with 2009 Distinguished Lecturer
Prof. Simon Gaskell
Director of the Michael Barber Centre for Mass Spectrometry and Vice President (Research)
The University of Manchester
speaking on
“Mass spectrometric and ion mobility studies of the gas-phase ion chemistry of peptides”
at The Hilton at East Brunswick in East Brunswick, NJ
Photos from the 2009 Fall Vendor Show
1. Front: Kathleen Cox, Professor Simon Gaskell, John Castoro.
Rear: Mingxiang Lin, Mickey O'Brien, Kathleen Anderson
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2. Professor Simon Gaskell presenting at the 2009 NJ MSDG vendor show
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Mass Spectrometry Awards
NJACS-MSDG sponsors five awards for the promotion of
mass spectrometry in the
greater New Jersey region.
(including New York/Connecticut/ Pennsylvania/Delaware).
[ Table of Past Awards ]
New Jersey Regional Award for Achievements in Mass Spectrometry
[ Eligibility/Nomination Form
]
New Jersey Early Career Award in Mass Spectrometry
[ Eligibility/Nomination Form
]
New Jersey Distinguished Service Award in Mass Spectrometry
[ Eligibility/Nomination Form
]
NJACS-MSDG Student Travel Award
[ Eligibility/Nomination Form
]
NJACS-MSDG Distinguished Lectureship
Please Note:
Nominations for NJACS MSDG awards are open for 2011.
Please see the
eligibility forms
for further information.
Student ASMS Travel Award application is due April 19, 2010.
Early Career Award, Distinguished Service Award, and Regional
Achievement Award applications are due
October 8, 2010.
Recent Meeting
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The NJ Mass Spectrometry Discussion Group
Proudly Presents our
February
Meeting
Sponsored by
Bruker Daltonics
at the
Holiday Inn,
Somerset, NJ
on
Tuesday,
May 5, 2009
Presentation I:
“Comparisons of Data Independent LC-MS with Data Dependant LC-MS/MS on a Quadrupole-Time of Flight Hybrid Mass Spectrometer”
Ignatius Kass, Ph.D
Waters Corporation - Field Marketing Manager, Pharmaceutical Mass Spectrometry
Presentation II:
“Formation of reactive metabolites by cytochrome P450-dependent oxidation versus glucuronidation”
Joanna Barbara, Ph.D
XenoTech LLC. - Mass Spectrometry Specialist
Presentation II:
“Formation of reactive metabolites by cytochrome P450-dependent oxidation versus glucuronidation”
Joanna Barbara, Ph.D
XenoTech LLC. - Mass Spectrometry Specialist
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