North Jersey Section
American Chemical Society

Jun 21, 2017 – NMR Topical Group Meeting

The North Jersey ACS NMR Topical Group is pleased to presents its June meeting at Princeton, Wednesday, June 21, 2017  [ register ]

Featured Presentation

Dr. Yongchao Su

Merck Research Laboratories, West Point, PA

“Molecular Investigation of Pharmaceutical Formulations in Preclinical Development”

Abstract:

Chemical and physical stability of drug substances in pharmaceutical dosages exhibits critical attributes in preclinical development. This presentation will try to elaborate the molecular structure related risks in formulation design and how NMR is employed to tackle these analytical challenges. The contents will cover structural investigation of drug products from solid dosages of small molecule drugs and parenteral formulation of peptides. Chemical and biophysical events including phase conversion of crystalline or amorphous active pharmaceutical ingredients, aggregation of peptides, stabilizing and destabilizing interactions in multicomponent formulations will be discussed. Successful examples utilizing dynamic nuclear polarization (DNP) and proton detection under ultra-fast spinning in practical formulation characterization will be included, as efforts to advance solid-state NMR technologies in pharmaceutical sciences.

Program

6:00 pm   Dinner
7:00 pm  Seminar

Dinner Cost:

$15 employed / $5 students, postdoc, retired, unemployed. No charge for seminar only.

Meeting Venue

Where: Frick Chemistry Atrium (dinner), Frick Chemistry room A57 (seminar)
Princeton University
Princeton, NJ 08544  [ directions ]

Parking: Parking will be available in Lot 21 (see map link given above under Directions)

Public Transit: It is possible to take NJ Transit all the way to Princeton campus (the symposium location is ~ 10 min walk from the train station). Take the Northeast Corridor NJ transit train to Princeton Junction, then transfer to the small “dinky” train that ends on campus (5 min train ride).

Questions:

Anuji.Abraham@bms.com (Chair) or Mary.Harner@bms.com (Co-chair)

Register:

Please register online here
or via e-mail to Anuji.Abraham@bms.com or Mary.Harner@bms.com

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