North Jersey Section
American Chemical Society

Drug Metabolism Topical Group Meetings

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(Past Event)

Apr 20, 2017 – DMDG Spring Symposium and Vendor Exhibition

NJ-DMDG

2017 Spring Symposium & Vendor Exhibition

Sponsored by the

North Jersey ACS Drug Metabolism Discussion Group

“Translating Preclinical Drug Disposition in Clinical Development

Date:    April 20, 2017
Time:    8:00 am – 3:45 pm
Venue:  The Palace at Somerset Park, 333 Davidson Avenue, Somerset, NJ 08873 [ directions ]

Registration Information:

  • Pre-registration fee is $125 (pre-register by April 15, 2017).
  • Registration fee at the door is $150 (Checks only)
  • Registration fee is $10 for students and postdocs and $50 for faculty
  • Registration is free for unemployed

Please plan to pre-register as a group, as coordinated by a member of the NJACS DMDG Steering Committee List, below, from your organization.

  • If you have no DMDG member at your company, please contact Bo Wen (bo.1.wen@gsk.com) for registration.
  • Payments by personal or company checks. Sorry, credit cards are not accepted.
  • Checks should be made payable to: NJ Drug Metabolism Discussion Group.

Exhibitors:

  • Please contact Anima Ghosal (ghosala@aol.com) for information concerning exhibits

Program

“Translating Preclinical Drug Disposition in Clinical Development

8:00 a.m.

Registration / Continental Breakfast / Vendor Exhibit

9:00 a.m.

Introductory Remarks

Bo Wen, Chair, NJ DMDG

9:10 a.m.

Metabolomic and Transcriptomic Analysis of BCRP/Abcg2 and PGP/Abcb1 WT and Double KO Rat Tissues to Identify Endogenous, Dietary and Xenobiotic Substrates

Erin Schuetz, PhD, Member, Department of Pharmaceutical Sciences, St Jude Children’s Research Hospital, Memphis, TN

10:00 a.m.

Assays to Guide the Way at NCATS: Drug Transporters and Drug Efficacy

Matthew Hall, PhD, Biology Group Leader, National Center for Advancing Translational Sciences (NCATS) Chemical Genomics Center, National Institutes of Health, Rockville, MD

10:45 a.m.

Vendor Exhibit & Coffee Break

11:30 p.m.

Emerging Role of Non-P450 Enzymes in Drug Metabolism and Toxicity

Deepak Dalvie, PhD, Sr. Principal Investigator, Department of Drug Metabolism and Pharmacokinetics, Celgene, San Diego, CA

12:15 p.m.

Lunch & Vendor Exhibit

1:45 p.m.

Is it Possible to Accurately Predict the Risk that a Drug Candidate Will Cause Idiosyncratic Drug Reactions?

Jack Uetrecht, PhD, Professor of Pharmacy and Medicine and the Canada Research Chair in Adverse Drug Reactions, University of Toronto, Toronto, Ontario, Canada

2:30 p.m.

Vendor Exhibit & Coffee Break

3:00 p.m.

ADME Analysis of Therapeutic Peptides: Preserving Product Value

Jerome Hochman, PhD, Sr. Principal Scientist, Department of Pharmacokinetics Pharmacodynamics and Drug Metabolism, Merck & Co. West Point, PA

3:45 p.m.

Program Closure



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NJ-DMDG Steering Committee 2016-2017
Name Company E-mail address Responsibility
Bo Wen GSK bo.1.wen@gsk.com Chair, 2016-17
Manthena Varma Pfizer Manthena.V.Varma@pfizer.com Chair Elect, 2017-18
Zhao pie Zeng Sanofi Zhaopie.Zeng@sanofi-aventis.com Treasurer
Anima Ghosal Kean Univ ghosala@aol.com Vendor Liaison
Lauren Aleksunes Rutgers Univ aleksunes@eohsi.rutgers.edu Past Chair, 2015-16
Richard Tschirret-Guth Merck richard_tschirretguth@merck.com Past Chair, 2014-15
Wing Lam Janssen R&D wlam@its.JnJ.com Past Chair, 2013-14
Allen Jones   allen.n.jones@verizon.net Past Chair, 2012-13
Lian Zhou BMS Lian.zhou@bms.com Past Chair, 2011-12
Imad Hanna Novartis imad.hanna@novartis.com Member
Ron Kong PTC Therapeutics rkong@ptcbio.com Member
Lei Tang Sanofi Lei.Tang@sanofi-aventis.com Member
Li Yu Roche li.yu.ly1@roche.com Member
Yaofeng Cheng BMS Yaofeng.Cheng@bms.com Member
Virna Schuck Novartis virna.schuck@novartis.com Member
Naiyu Zheng BMS naiyu.zheng@bms.com Member
Beth Joshi Merck elizabeth.joshi@merck.com Member
Matthew Hoffmann Celgene mjhoffman@celgene.com Member
Karen H. Dingley Celgene kdingley@celgene.com Member
Carolina Berthiaume   carolina.berthiaume@gmail.com Member
Maria Markowska   cMmaryla5@yahoo.com Member


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Directions to the Palace at Somerset Park

    333 Davidson Avenue, Somerset, NJ 08873
    Phone: 732-302-9922

From the New Jersey Turnpike:

    Exit 10 to Interstate 287 North.
    Follow 10 miles to Exit 10 (527 New Brunswick -- South Bound Brook).
    Take Easton Ave towards South Bound Brook to first light,
    make left (Davidson Ave.)

From New York City:

    Lincoln Tunnel to N.J. Turnpike South.
    Follow N.J. Turnpike directions mentioned above.

From Route 287:

    If traveling north:
      Exit 10 (527 New Brunswick -- South Bound Brook).
      Follow sign towards Bound Brook, to light
      make left (Davidson Ave.)
    If traveling south:
      Exit 10 (527 New Brunswick).
      Left on Easton Ave., to light,
      make left (Davidson Ave).

From Newark Airport:

    Take NJ Turnpike South to Exit 10
    I-287 North to Exit 10 (Easton Ave)
    at first light, go left on Davidson Ave.
    Hotel immediately on left.

top

2017-04-20

(Past Event)

Oct 13, 2016 – DMDG Fall Symposium and Vendor Exhibition

NJ-DMDG

2016 Fall Symposium & Vendor Exhibition

Sponsored by the

North Jersey ACS Drug Metabolism Discussion Group

“Transforming assessment of Drug Disposition with Novel Methodologies”

Date:    October 13, 2016
Time:    8:00 am – 3:45 pm
Venue:  The Palace at Somerset Park, 333 Davidson Avenue, Somerset, NJ 08873 [ directions ]

Registration Information:

  • Pre-registration fee is $125 (pre-register by Oct 6, 2016).
  • Registration fee at the door is $150 (Checks only)
  • Registration fee is $10 for students and postdocs and $50 for faculty
  • Registration is free for unemployed

Please plan to pre-register as a group, as coordinated by a member of the NJACS DMDG Steering Committee List, below, from your organization.

  • If you have no DMDG member at your company, please contact Bo Wen (bo.1.wen@gsk.com) for registration.
  • Payments by personal or company checks. Sorry, credit cards are not accepted.
  • Checks should be made payable to: NJ Drug Metabolism Discussion Group.

Exhibitors:

  • Please contact Anima Ghosal (ghosala@aol.com) for information concerning exhibits

Program

“Translational Advances in Drug Disposition and Toxicity:
Emerging Technologies and Tools”

8:00 a.m.

Registration / Continental Breakfast / Vendor Exhibit

9:00 a.m.

Introductory Remarks

Bo Wen, Chair, NJ DMDG

9:10 a.m.

Predicting Transporter-Based Systemic and Tissue Drug Disposition Using Quantitative Proteomics and PET Imaging

Jashvant Unadkat, PhD, Professor, Department of Pharmaceutics, University of Washington, Seattle, WA

10:00 a.m.

Decoding Host-Microbe Communication Through Metabolomics

Andrew Patterson, PhD, Associate Professor, Department of Veterinary and Biomedical Sciences, Pennsylvania State University, University Park, PA

10:45 a.m.

Vendor Exhibit & Coffee Break

11:30 p.m.

Drug Metabolism Enzyme and Transporter Pharmacogenetics in Drug Development: Industry Practices and Challenges

William Brian, PhD, Senior Director, Department of Translational Medicine and Early Development (TMED), Sanofi, Bridgewater, NJ

12:15 p.m.

Lunch & Vendor Exhibit

1:45 p.m.

Transporter-Mediated Asymmetric Tissues Disposition for Drug Efficacy and Toxicity: Opportunities and Challenges in Translation

Yurong Lai, PhD, Sr. Principal Scientist, Department of Pharmaceutical Candidate Optimization, Bristol-Myers Squibb, Princeton, NJ

2:30 p.m.

Vendor Exhibit & Coffee Break

3:00 p.m.

How Can The Evolution of LC/MS Technology Enable Drug Metabolism Scientists to Continue Their Remarkable Contributions to Drug Discovery and Development?

Mingshe Zhu, PhD, Principal Scientist, Department of Biotransformation, Bristol-Myers Squibb, Princeton, NJ

3:45 p.m.

Program Closure



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NJ-DMDG Steering Committee 2016-2017
Name Company E-mail address Responsibility
Bo Wen GSK bo.1.wen@gsk.com Chair, 2016-17
Manthena Varma Pfizer Manthena.V.Varma@pfizer.com Chair Elect, 2017-18
Zhao pie Zeng Sanofi Zhaopie.Zeng@sanofi-aventis.com Treasurer
Anima Ghosal Kean Univ ghosala@aol.com Vendor Liaison
Lauren Aleksunes Rutgers Univ aleksunes@eohsi.rutgers.edu Past Chair, 2015-16
Richard Tschirret-Guth Merck richard_tschirretguth@merck.com Past Chair, 2014-15
Wing Lam Janssen R&D wlam@its.JnJ.com Past Chair, 2013-14
Allen Jones   allen.n.jones@verizon.net Past Chair, 2012-13
Lian Zhou BMS Lian.zhou@bms.com Past Chair, 2011-12
Imad Hanna Novartis imad.hanna@novartis.com Member
Ron Kong PTC Therapeutics rkong@ptcbio.com Member
Lei Tang Sanofi Lei.Tang@sanofi-aventis.com Member
Li Yu Roche li.yu.ly1@roche.com Member
Yaofeng Cheng BMS Yaofeng.Cheng@bms.com Member
Virna Schuck Novartis virna.schuck@novartis.com Member
Naiyu Zheng BMS naiyu.zheng@bms.com Member
Beth Joshi Merck elizabeth.joshi@merck.com Member
Matthew Hoffmann Celgene mjhoffman@celgene.com Member
Karen H. Dingley Celgene kdingley@celgene.com Member
Carolina Berthiaume   carolina.berthiaume@gmail.com Member
Maria Markowska   cMmaryla5@yahoo.com Member


top

Directions to the Palace at Somerset Park

    333 Davidson Avenue, Somerset, NJ 08873
    Phone: 732-302-9922

From the New Jersey Turnpike:

    Exit 10 to Interstate 287 North.
    Follow 10 miles to Exit 10 (527 New Brunswick -- South Bound Brook).
    Take Easton Ave towards South Bound Brook to first light,
    make left (Davidson Ave.)

From New York City:

    Lincoln Tunnel to N.J. Turnpike South.
    Follow N.J. Turnpike directions mentioned above.

From Route 287:

    If traveling north:
      Exit 10 (527 New Brunswick -- South Bound Brook).
      Follow sign towards Bound Brook, to light
      make left (Davidson Ave.)
    If traveling south:
      Exit 10 (527 New Brunswick).
      Left on Easton Ave., to light,
      make left (Davidson Ave).

From Newark Airport:

    Take NJ Turnpike South to Exit 10
    I-287 North to Exit 10 (Easton Ave)
    at first light, go left on Davidson Ave.
    Hotel immediately on left.

top

2016-10-13

(Past Event)

April 14, 2016 – DMDG Spring Symposium and Vendor Exhibition

NJ-DMDG

Drug Met Symposium and Vendor Show

                [ back ]
Date:   April 14, 2016
Venue: The Palace at Somerset Park, 333 Davidson Avenue, Somerset, NJ 08873.

Mark your calendars for The North Jersey Drug Metabolism Discussion Group Spring 2016 Symposium and Vendor Exhibition, to be held at The Palace at Somerset Park, 333 Davidson Avenue, Somerset, NJ 08873, on Thursday, April 14, from 8:00-4:00 PM.

Registration Information:

Pre-registration fee is $125 (pre-register by 7 April 2016).

Registration fee at the door is $150 (Checks only)

Registration fee is $10 for students and postdocs and $50 for faculty

Registration is free for unemployed

Please plan to pre-register as a group, as coordinated by a member of the NJACS DMDG steering committee from your organization (see list).

  • If you have no DMDG member at your company, please contact Richard Lauren Aleksunes       (aleksunes@eohsi.rutgers.edu) for registration.
  • Payments by personal or company checks.  Sorry, credit cards are not accepted.
  • Checks should be made payable to: NJ Drug Metabolism Discussion Group.

Exhibitors:

2016 Spring Symposium and Vendor Exhibition

Sponsored by the

North Jersey ACS

Drug Metabolism Discussion Group

“Transforming assessment of Drug Disposition with Novel Methodologies”

The Palace at Somerset Park, 333 Davidson Avenue Somerset, New Jersey

14 April, 2016 8:00 am – 4:00 pm

Program

“Transforming assessment of Drug Disposition with Novel Methodologies”

8:00 a.m.

Registration / Continental Breakfast / Vendor Exhibit

9:00 a.m.

Introductory Remarks

Lauren Aleksunes, Chair, NJDMDG

9:10 a.m.

Topic:  Application of Engineered Mouse Models for Xenobiotic Disposition Studies

Xinxin Ding, SUNY Polytechnic Institute

10:00 a.m.

Topic:  Challenges in Identifying Biomarkers for Transporter-Mediated Drug-Drug Interactions in Liver and Kidney

Raymond Evers, Merck & Co.

10:45 a.m.

Vendor Exhibit & Coffee Break

11:30 p.m.

Topic: Microsampling in Nonclinical Studies: Where are We Now?

Laura Patrone, Bristol-Myers Squibb

12:15 p.m.

Lunch & Vendor Exhibit

1:45 p.m.

Topic: MALDI Imaging MS: Seeing Drug ADME in Tissues at Last

Stephen Castellino, GlaxoSmithKline

2:30 p.m.

Vendor Exhibit & Coffee Break

3:00 p.m.

Topic: Validation of an Integrated Series of Ligand Binding Assays for the Quantitative Determination of Antibody Drug Conjugates in Biological Matrices

Heather Myler, Bristol-Myers Squibb

3:45 p.m.

Program Closure

 

 

2016-04-14

(Past Event)

October 15, 2015 – DMDG Spring Symposium and Vendor Exhibition

NJ-DMDG

Drug Met Symposium and Vendor Show

                [ back ]
Date:   October 15, 2015
Venue: The Palace at Somerset Park, 333 Davidson Avenue, Somerset, NJ 08873.

Mark your calendars for The North Jersey Drug Metabolism Discussion Group Spring 2015 Symposium and Vendor Exhibition, to be held at The Palace at Somerset Park, 333 Davidson Avenue, Somerset, NJ 08873, on Monday, October 15, from 8:00-4:00 PM.

Registration Information:

Pre-registration fee is $125 (pre-register by 15 October 2015).

Registration fee at the door is $150 (Checks only)

Registration fee is $10 for students and postdocs and $50 for faculty

Registration is free for unemployed

Please plan to pre-register as a group, as coordinated by a member of the NJACS DMDG steering committee from your organization (see list).

·         If you have no DMDG member at your company, please contact Richard Tschirret-Guth       (richard_tschirretguth@merck.com) for registration.

·         Payments by personal or company checks.  Sorry, credit cards are not accepted.

·         Checks should be made payable to: NJ Drug Metabolism Discussion Group.

Exhibitors:

·         Please contact Karen Dingley (karen_dingley@merck.com) for information concerning exhibits

2015 Fall Symposium and Vendor Exhibition

Sponsored by the

North Jersey ACS

Drug Metabolism Discussion Group

“Strategies to Predict and Reduce Drug Interactions and Toxicities”

The Palace at Somerset Park 333 Davidson Avenue Somerset, New Jersey 15 October, 2015 8:00 am – 3:45 pm

Program

“Recent Advances in Drug Distribution and Drug Action”

8:00 a.m.

Registration / Continental Breakfast / Vendor Exhibit

9:00 a.m.

Introductory Remarks

Richard Tschirret-Guth, Chair, NJDMDG

9:10 a.m.

Topic:  Identifying Strategies to Prevent Antiretroviral Drug-induced Toxicities

Namandje Bumpus, Johns Hopkins School of Medicine

10:00 a.m.

Topic:  Targeted Pharmacological Control of the Microbiome to Improve Human Health

Matthew Redinbo, University of North Carolina at Chapel Hill

10:45 a.m.

Vendor Exhibit & Coffee Break

11:30 p.m.

Topic: Toxicity Prediction and Development of Pharmacogenetic Co-Diagnostics Using Diversity Outbred Mice

Alison Harrill, University of Arkansas for Medical Sciences

12:15 p.m.

Lunch & Vendor Exhibit

1:45 p.m.

Topic: Renal Drug Interactions: Progress and Challenges in Making Predictions in a Complex System

Adrian Ray, Gilead Sciences

2:30 p.m.

Vendor Exhibit & Coffee Break

3:00 p.m.

Topic: Cynomolgus Monkey as a Potential Model to Assess Drug Interactions involving Hepatic OATP Transporters: In Vitro, In Vivo, and In Vitro-to-In Vivo Extrapolation

Hong Shen, Bristol-Myers Squibb

3:45 p.m.

Program Closure

 

 

2015-10-15

(Past Event)

April 27, 2015 – DMDG Spring Symposium and Vendor Exhibition

NJ-DMDG

Drug Met Symposium and Vendor Show

                [ back ]
Date:   April 27, 2015
Venue: The Palace at Somerset Park, 333 Davidson Avenue, Somerset, NJ 08873.

Mark your calendars for The North Jersey Drug Metabolism Discussion Group Spring 2015 Symposium and Vendor Exhibition, to be held at The Palace at Somerset Park, 333 Davidson Avenue, Somerset, NJ 08873, on Monday, April 27, from 8:00-4:00 PM.

Registration Information:

Pre-registration fee is $125 (pre-register by 17 April 2015).

Registration fee at the door is $150 (Checks only)

Registration fee is $10 for students and postdocs and $50 for faculty

Registration is free for unemployed

Please plan to pre-register as a group, as coordinated by a member of the NJACS DMDG steering committee from your organization (see list).

·         If you have no DMDG member at your company, please contact Richard Tschirret-Guth       (richard_tschirretguth@merck.com) for registration.

·         Payments by personal or company checks.  Sorry, credit cards are not accepted.

·         Checks should be made payable to: NJ Drug Metabolism Discussion Group.

Exhibitors:

·         Please contact Karen Dingley (karen_dingley@merck.com) for information concerning exhibits

2015 Spring Symposium and Vendor Exhibition

Sponsored by the

North Jersey ACS

Drug Metabolism Discussion Group

“Recent Advances in Drug Distribution and Drug Action”

The Palace at Somerset Park 333 Davidson Avenue Somerset, New Jersey 27 April, 2015 8:00 am – 3:45 pm

Program

“Recent Advances in Drug Distribution and Drug Action”

8:00 a.m.

Registration / Continental Breakfast / Vendor Exhibit

9:00 a.m.

Introductory Remarks

Richard Tschirret-Guth, Chair, NJDMDG

9:10 a.m.

Topic:  Prediction of unbound intracellular drug concentration in the presence of transporters: from in vitro to in vivo

Kenneth Korzekwa, PhD, Associate Professor Department of Pharmaceutical Sciences, School of Pharmacy, Temple University, Philadelphia, PA

10:00 a.m.

Topic:  Single cell pharmcokinetics

Greg Thurber, PhD, Assistant Professor, Department of Chemical Engineering, University of Michigan, Ann Arbor, MI  

10:45 a.m.

Vendor Exhibit & Coffee Break

11:30 p.m.

Topic: Imaging drug distribution and biomarker response in drug discovery

Paul J. McCracken, PhD, Director of Imaging, biomarkers and Personalized Medicine CFU, Eisai Product Creation Systems, Andover, MA

12:15 p.m.

Lunch & Vendor Exhibit

1:45 p.m.

Topic: Biomarkers identification/analysis in clinical research

Steven P. Piccoli, Ph.D. Research Fellow, Immunochemistry and Biomarker Development, Bristol-Myers Squibb, Princeton, NJ

2:30 p.m.

Vendor Exhibit & Coffee Break

3:00 p.m.

Topic: Systems pharmacology approach to drug disposition and action

James M. Gallo, PhD, Professor, Department of Pharmacology and Systems Therapeutics, Mount Sinai School of Medicine, New York, NY

3:45 p.m.

Program Closure

 

 

2015-04-27

(Past Event)

October 13, 2014 – DMDG Fall Symposium and Vendor Exhibition

NJ-DMDG

Drug Met Symposium and Vendor Show

                [ back ]

Date:   Oct 13, 2014 — 8:00 am – 4:00 pm
Venue: The Palace at Somerset Park, 333 Davidson Avenue, Somerset, NJ 08873.

Mark your calendars for the The North Jersey Drug Metabolism Discussion Group Fall Symposium and Vendor Exhibition, to be held at The Palace at Somerset Park, 333 Davidson Avenue, Somerset, NJ 08873, on Monday, October 13, from 8:00-4:00 PM. Additional details will be posted in September.


Current DMDG Board Members:

 

  Name   Company   Email   Role

Richard Tschirret-Guth

Merck Research

richard_tschirretguth@merck.com

Chair 2014-15

Lauren Aleksunes

Rutgers University

aleksunes@eohsi.rutgers.edu

Chair-elect, 2015-16

Matthew Hoffmann

Celgene

mjhoffman@celgene.com

Treasurer

Karen H. Dingley

Merck Research

karen_dingley@merck.com

Vendor Liaison

Wing Lam

Janssen R&D

wlam@its.JnJ.com

Past-Chair, 2013-14

Allen Jones

allen.n.jones@verizon.net

Past Chair, 2012-13

Lian Zhou

BMS

Lian.zhou@bms.com

Past Chair, 2011-12

Imad Hanna

Novartis

imad.hanna@novartis.com

Past Chair, 2010-11

Roseann Affinito

KCAS Bio

roseannaffinito@optonline.net

Member

Shiying Chen

Merck Research

shiying.chen@merck.com

Member

Ron Kong

PTC Therapeutics

rkong0605@gmail.com

Member

Maria Markowska

 

Mmaryla5@yahoo.com

Member

Zhao pie Zeng

Sanofi-aventis

Zhaopie.Zeng@sanofi-aventis.com

Member

Lei Tang

Sanofi-aventis

Lei.Tang@sanofi-aventis.com

Member

Bo Wen

GSK

bo.1.wen@gsk.com

Member

Manthena Varma

Pfizer

Manthena.V.Varma@pfizer.com

Member

Li Yu

Roche

li.yu.ly1@roche.com

Member

Yaofeng Cheng

BMS

Yaofeng.Cheng@bms.com

Member

Carolina Cabral

 

cbcabral@gmail.com

Member

2014-10-13

(Past Event)

May 1, 2014 – DMDG Spring Symposium and Vendor Exhibition

NJ-DMDG

Drug Met Symposium and Vendor Show

                [ back ]

Date:   May 1, 2014
Venue: The Palace at Somerset Park, 333 Davidson Avenue, Somerset, NJ 08873.

2014 Spring Symposium and Vendor Exhibition

Sponsored by the

North Jersey ACS

Drug Metabolism Discussion Group

“Effect of gender, hepatic and renal function on the systemic clearance of small molecules/biotherapeutics and anti-HCV polypharmacy”

The Palace at Somerset Park
333 Davidson Avenue
Somerset, New Jersey
1 May, 2014
8:00 am – 3:45 pm

Program

“Effect of gender, hepatic and renal function on the systemic clearance of small molecules/biotherapeutics and anti-HCV polypharmacy”

8:00 a.m.

Registration / Continental Breakfast / Vendor Exhibit

9:00 a.m.

Introductory Remarks

Dr. Wing Lam, Chair, NJDMDG

9:10 a.m.

FXR and Liver Functions

Grace L. Guo, MBBS, PhD, Associate Professor, Department of Pharmacology and Toxicology, Ernst Mario School of Pharmacy, the Environmental and Occupational Health Sciences Institute, Rutgers University, Piscataway, NJ

10:00 a.m.

The Clearance of Drugs and Biologics in Human Models of Kidney Disease

Melanie S. Joy, PharmD, PhD, FCCP, FASN, Department of Pharmaceutical Sciences, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of Colorado Anschutz Medical Campus, Aurora, CO  

10:45 a.m.

Vendor Exhibit & Coffee Break

11:30 p.m.

Hypnotic Drugs, Gender, and the FDA

David J. Greenblatt, MD, Professor of Pharmacology and Experimental Therapeutics, Tufts University School of Medicine and Tufts Medical Center,
Boston, MA

12:15 p.m.

Lunch & Vendor Exhibit

1:45 p.m.

Quantitative Pharmacology in Biotherapeutics Development

Honghui Zhou, PhD, Senior Director and Janssen Fellow, Head, Pharmacokinetics and Pharmacodynamics, Biologics Clinical Pharmacology, Biotechnology CoE, Janssen Research & Development, LLC., Spring House, PA  

2:30 p.m.

Vendor Exhibit & Coffee Break

3:00 p.m.

The Clinical Pharmacology of Anti-HCV Agents

Steven J. Kovacs, PharmD, Director, Translational Medicine, Novartis Institutes for Biomedical Research , East Hanover, NJ

3:45 p.m.

Program Closure

 

2013 DMDG Board Members:

 

  Name   Company   Email   Role

Wing Lam

Janssen R&D

wlam@its.JnJ.com

Chair, 2013-14

Richard Tschirret-Guth

Merck Research

richard_tschirretguth@merck.com

Chair-elect 2014-15

Matthew Hoffmann

Celgene

mjhoffman@celgene.com

Treasurer

Karen H. Dingley

Merck Research

karen_dingley@merck.com

Vendor Liaison

Allen Jones

Alliance Technologies

allen.n.jones@verizon.net

Past Chair, 2012-13

Lian Zhou

BMS

Lian.zhou@bms.com

Past Chair, 2011-12

Imad Hanna

Novartis

imad.hanna@novartis.com

Past Chair, 2010-11

Roseann Affinito

KCAS Bio

roseannaffinito@optonline.net

Member

Lauren Aleksunes

Rutgers University

aleksunes@eohsi.rutgers.edu

Member

Shiying Chen

Merck Research

shiying.chen@merck.com

Member

Karl Frank

 

kbfrank3@verizon.net

Member

Ron Kong

PTC Therapeutics

rkong0605@gmail.com

Member

Maria Markowska

 

Mmaryla5@yahoo.com

Member

Zhao pie Zeng

Sanofi-aventis

Zhaopie.Zeng@sanofi-aventis.com

Member

Lei Tang

Sanofi-aventis

Lei.Tang@sanofi-aventis.com

Member

Richard Tschirret-Guth

Merck Research

richard_tschirretguth@merck.com

Member

Bo Wen

GSK

bo.1.wen@gsk.com

Member

Manthena Varma

Pfizer

Manthena.V.Varma@pfizer.com

Member

Li Yu

Roche

li.yu.ly1@roche.com

Member

Yaofeng Cheng

BMS

Yaofeng.Cheng@bms.com

Member

Carolina Cabral

 

cbcabral@gmail.com

Member

 

 

2014-05-01

(Past Event)

Oct 17, 2013 – DMDG Fall Symposium and Vendor Show

NJ-DMDG

Drug Met Symposium and Vendor Show

[ back ]

Date:   October 17, 2013
Venue: The Palace at Somerset Park, 333 Davidson Avenue, Somerset, NJ 08873.

2009 Fall Symposium and Vendor Exhibition

2013 Fall Symposium and Vendor Exhibition

Sponsored by the

North Jersey ACS

Drug Metabolism Discussion Group

“Biomarkers, Reactive Metabolites, Idiosyncratic Reactions”

The Palace at Somerset Park
333 Davidson Avenue
Somerset, New Jersey 08873
17 October, 2013
8:00 am – 3:45 pm

Program

Biomarkers, Reactive Metabolites, Idiosyncratic Reactions

8:00 a.m.

Registration / Continental Breakfast / Vendor Exhibit

9:00 a.m.

Introductory Remarks

Dr. Wing Lam, Chair, NJDMDG

9:10 a.m.

Exploring the Mechanism of Metabolic Intermediate Complex-Based Metabolism-Dependent CYP Inhibition: the Case of Lapatinib

Joanna Barbara, Ph.D., Director of Analytical Services, XenoTech, Lenexa, KS

10:00 a.m.

Altered Drug Metabolism During Pregnancy

Hyunyoung (Young) Jeong, Pharm.D., Ph.D., Associate Professor, Department of Pharmacy Practice and Biopharmaceutical Sciences, University of Illinois at Chicago, Chicago, IL

10:45 a.m.

Vendor Exhibit & Coffee Break

11:30 p.m.

Molecular Imaging Biomarkers for Predicting Treatment Response

Paul D. Acton, Ph.D., Scientific Director & Janssen Fellow, Global Head, Molecular Imaging, Janssen Research and Development, Spring House, PA

12:15 p.m.

Lunch & Vendor Exhibit

1:45 p.m.

Why are Idiosyncratic Drug Reactions Idiosyncratic 

Jack Uetrecht, M.D., Ph.D., Professor of Pharmacy and Medicine, University of Toronto, Toronto, ON

2:30 p.m.

Vendor Exhibit & Coffee Break

3:00 p.m.

Coadministration of Ritonavir (RTV) with the HCV Protease Inhibitor Danoprevir (DNV) Substantially Reduces Reactive Metabolite Formation: In Vitro and In Vivo Data

Bonnie Brennan , Pharm.D., Senior Principal Scientist, Department of Clinical Pharmacology at Roche, Nutley, NJ  

3:45 p.m.

Program Closure

 NJ-DMDG Steering Committee 2013-2014:

Name

Company

E-mail address

Role

Wing Lam

Janssen R&D

wlam@its.JnJ.com

Chair, 2013-14

Philip Krieter

Warner Chilcott

pakrieter@verizon.net

Treasurer

Matthew Hoffmann

Celgene

mjhoffman@celgene.com

Vice-Treasurer

Karen H. Dingley

Merck Research

karen_dingley@merck.com

Vendor Liaison

Allen Jones

Roche

allen.n.jones@verizon.net

Past Chair, 2012-13

Lian Zhou

BMS

Lian.zhou@bms.com

Past Chair, 2011-12

Imad Hanna

Novartis

imad.hanna@novartis.com

Past Chair, 2010-11

Roseann Affinito

KCAS Bio

roseannaffinito@optonline.net

Member

Lauren Aleksunes

Rutgers University

aleksunes@eohsi.rutgers.edu

Member

Shiying Chen

Merck Research

shiying.chen@merck.com

Member

Karl Frank

Roche

karl_b.frank@roche.com

Member

Rong Kong

PTC Therapeutics

rkong@ptcbio.com

Member

Maria Markowska

Janssen R&D

MMarkows@its.jnj.com

Member

Zhao pie Zeng

Sanofi-aventis

Zhaopie.Zeng@sanofi-aventis.com

Member

Lei Tang

Sanofi-aventis

Lei.Tang@sanofi-aventis.com

Member

Richard Tschirret-Guth

Merck Research

richard_tschirretguth@merck.com

Member

Bo Wen

GSK

bo.1.wen@gsk.com

Member

Manthena Varma

Pfizer

Manthena.V.Varma@pfizer.com

Member

Li Yu

Roche

li.yu.ly1@roche.com

Member

Yaofeng Cheng

BMS

Yaofeng.Cheng@bms.com

Member

Carolina Cabral

 

cbcabral@gmail.com

Member

 

 

Registration:

Pre-registration fee is $125 (pre-register by 10 October 2013).

Registration is Free for students and unemployed (with proper identification).

Registration fee at the door is $150 (Checks only).

     Please plan to pre-register as a group, as coordinated by a member of the NJACS DMDG steering committee from your organization (see list above).

        If you have no DMDG member at your company, please contact Wing Lam (mwlam@its.jnj.com) for registration.

        Payments by personal or company checks.  Sorry, credit cards are not accepted. 

        Checks should be made payable to: NJ Drug Metabolism Discussion Group. 

        Please also visit our website: http://www.njacs.org/topical-groups/drug-metabolism 

 

Exhibitors:

       Please contact Karen Dingley (karen_dingley@merck.com) for information concerning exhibits


Directions to the Palace at SomersetPark

333 Davidson Avenue, Somerset, NJ 08873  08873   [ website ]

Phone: 732-302-9922

From the New Jersey Turnpike:

Exit 10 to Interstate 287 North.  Follow 10 miles to Exit 10 (527 New Brunswick-South Bound Brook).  Easton Ave towards South Bound Brook to first light, make left (Davidson Ave.)

From New York City:

Lincoln Tunnel to N.J. Turnpike South.  Follow N.J. Turnpike directions mentioned above.

From Route 287:

If traveling north:

Exit 10 (527 New Brunswick-South Bound Brook).  Follow sign towards Bound Brook, to light make left (Davidson Ave.)

If traveling south:

Exit 10 (527 New Brunswick).  Left on Easton Ave., to light, make left (Davidson Ave).

From the Newark Airport

Take NJ Turnpike South to Exit 10- I-287 North to Exit 10 (Easton Ave) to first light, go left on Davidson Ave. Hotel immediately on left.

2013-10-17

(Past Event)

Apr 18, 2013 – DMDG Spring Symposium & Vendor Show

“Models, Pharmacogenomics, Pharmacokinetics”

NJDMDG SymposiumVenue: Hotel Somerset Bridgewater (formerly Crowne Plaza, formerly Somerset Plaza), 110 Davidson Avenue, Somerset, NJ 08873. [ directions ]

Exhibitor Info

Please contact Karen Dingley at karen_dingley@merck.com for information concerning exhibits.

Program   [ program bookpdf ]

08:00 am — Registration / Continental Breakfast / Vendor Exhibit

09:00 am
Introductory Remarks
Dr. Allen Jones, Chair, NJDMDG

09:10 am
“Novel Hepatic Model Systems for Investigating Mechanisms of Drug-Induced
Liver Injury (DIU)”

Edward L. LeCluyse, Ph.D. , Associate Investigator Institute for Chemical Safety Sciences The Hamner Institutes for Health Sciences, Research Triangle Park, NC

10:00 am
“Pharmacogenomics in American Indian Populations”
Erica L. Woodahl, Ph.D. , Associate Professor Department of Biomedical and Pharmaceutical Sciences University of Montana, MT   [ slidespdf ]

10:45 am — Vendor Exhibit & Coffee Break

11:30 am
“Pharmacokinetics of Proteins and Peptides”
Joseph P. Balthasar, Ph.D. , Professor of Pharmaceutical Sciences, State University of New York at Buffalo, Buffalo, NY

12:15 pm — Lunch & Vendor Exhibit

1:45 pm
“Glucuronidation, sulfation, and pharmacokinetics of conjugated metabolite”
Swati Nagar, Ph.D. , Associate Professor, Temple University School of Pharmacy, Philadelphia, PA   [ slidespdf ]

2:30 pm — Vendor Exhibit & Coffee Break

3:00 pm
“A panel of translational xenoreceptor, cytochrome P450, transporter and transplanted liver humanized mouse models for improved prediction of drug responses in Man”
Nico Scheer, Ph.D., Head of the tADMETTM portfolio, Taconic Farms, Inc., Cranbury, NJ [ slidespdf ]

3:45 pm — Program Closure


Directions to the Hotel Somerset Bridgewater

Hotel Somerset Bridgewater was formerly Crowne Plaza, formerly Somerset Plaza
110 Davidson Avenue, Somerset, NJ 08873
Phone: 732-560-0500

  • From the New Jersey Turnpike:
    Exit 10 to Interstate 287 North. Follow 10 miles to Exit 10 (527 New Brunswick-South Bound Brook). Easton Ave towards South Bound Brook to first light, make left (Davidson Ave.)
  • From New York City:
    Lincoln Tunnel to N.J. Turnpike South. Follow N.J. Turnpike directions mentioned above.
  • From Route 287:
    • If traveling north: Exit 10 (527 New Brunswick-South Bound Brook). Follow sign towards Bound Brook, to light make left (Davidson Ave.)
    • If traveling south: Exit 10 (527 New Brunswick). Left on Easton Ave., to light, make left (Davidson Ave).
  • From the Newark Airport
    Take NJ Turnpike South to Exit 10- I-287 North to Exit 10 (Easton Ave) to first light, go left on Davidson Ave. Hotel immediately on left.

2013-04-18

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